Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Tamarand L. Darling"'
Autor:
Moriya Tsuji, Manoj S. Nair, Kazuya Masuda, Candace Castagna, Zhenlu Chong, Tamarand L. Darling, Kuljeet Seehra, Youngmin Hwang, Ágata Lopes Ribeiro, Geovane Marques Ferreira, Laura Corredor, Jordana Grazziela Alves Coelho-dos-Reis, Yukiko Tsuji, Munemasa Mori, Adrianus C. M. Boon, Michael S. Diamond, Yaoxing Huang, David D. Ho
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
Abstract Prophylactic vaccines for SARS-CoV-2 have lowered the incidence of severe COVID-19, but emergence of viral variants that are antigenically distinct from the vaccine strains are of concern and additional, broadly acting preventive approaches
Externí odkaz:
https://doaj.org/article/3c17b40c03bf443c9109bfca507c868b
Autor:
Christina M. Kackos, Sherri L. Surman, Bart G. Jones, Robert E. Sealy, Trushar Jeevan, Christopher J. H. Davitt, Sergei Pustylnikov, Tamarand L. Darling, Adrianus C. M. Boon, Julia L. Hurwitz, Marcelo M. Samsa, Richard J. Webby
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 1 (2023)
ABSTRACT The novel coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), was identified in December of 2019 and is responsible for millions of infections and deaths across the globe. Vaccination against SARS-CoV-2 has proven effe
Externí odkaz:
https://doaj.org/article/4e606723ff53413194b0c6a9be5ac4ad
Autor:
Adrianus C. M. Boon, Tamarand L. Darling, Peter J. Halfmann, John Franks, Richard J. Webby, Dan H. Barouch, Julia R. Port, Vincent J. Munster, Michael S. Diamond, Yoshihiro Kawaoka
Publikováno v:
PLoS Pathogens, Vol 18, Iss 12 (2022)
Externí odkaz:
https://doaj.org/article/16f8b2100bd7425e86fed78070a352f4
Autor:
Juhee Son, Shimeng Huang, Qiru Zeng, Traci L. Bricker, James Brett Case, Jinzhu Zhou, Ruochen Zang, Zhuoming Liu, Xinjian Chang, Tamarand L. Darling, Jian Xu, Houda H. Harastani, Lu Chen, Maria Florencia Gomez Castro, Yongxiang Zhao, Hinissan P. Kohio, Gaopeng Hou, Baochao Fan, Beibei Niu, Rongli Guo, Paul W. Rothlauf, Adam L. Bailey, Xin Wang, Pei-Yong Shi, Elisabeth D. Martinez, Steven L. Brody, Sean P. J. Whelan, Michael S. Diamond, Adrianus C. M. Boon, Bin Li, Siyuan Ding
Publikováno v:
mBio, Vol 13, Iss 1 (2022)
ABSTRACT Pathogenic coronaviruses are a major threat to global public health. Here, using a recombinant reporter virus-based compound screening approach, we identified small-molecule inhibitors that potently block the replication of severe acute resp
Externí odkaz:
https://doaj.org/article/9c29ed90b7cd4b61b729c1e9c1dba354
Autor:
Caleb D. Swaim, Varun Dwivedi, Yi-Chieh Perng, Xu Zhao, Larissa A. Canadeo, Houda H. Harastani, Tamarand L. Darling, Adrianus C.M. Boon, Deborah J. Lenschow, Viraj Kulkarni, Jon M. Huibregtse
Publikováno v:
iScience, Vol 24, Iss 10, Pp 103213- (2021)
Summary: The emergence of SARS-CoV-2 has led to a global health crisis that, in addition to vaccines and immunomodulatory therapies, calls for the identification of antiviral therapeutics. The papain-like protease (PLpro) activity of nsp3 is an attra
Externí odkaz:
https://doaj.org/article/2d628d8bb0d24099b4370a53d4b95c2c
Autor:
Wen Su, Sin Fun Sia, Aaron J. Schmitz, Traci L. Bricker, Tyler N. Starr, Allison J. Greaney, Jackson S. Turner, Bassem M. Mohammed, Zhuoming Liu, Ka Tim Choy, Tamarand L. Darling, Astha Joshi, Ka Man Cheng, Alvina Y. L. Wong, Houda H. Harastani, John M. Nicholls, Sean P. J. Whelan, Jesse D. Bloom, Hui-Ling Yen, Ali H. Ellebedy, Adrianus C. M. Boon
Publikováno v:
mBio, Vol 12, Iss 5 (2021)
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein is the main target for neutralizing antibodies. These antibodies can be elicited through immunization or passively transferred as therapeutics in the form of convalescent-
Externí odkaz:
https://doaj.org/article/59017aa8fbfc49cca3569388d8d7b51e
Autor:
Baoling Ying, Tamarand L. Darling, Pritesh Desai, Chieh-Yu Liang, Igor P. Dmitriev, Nadia Soudani, Traci Bricker, Elena A. Kashentseva, Houda Harastani, Aaron G. Schmidt, David T. Curiel, Adrianus C.M. Boon, Michael S. Diamond
Publikováno v:
bioRxiv
We previously described a nasally delivered monovalent adenoviral-vectored SARS- CoV-2 vaccine (ChAd-SARS-CoV-2-S, targeting Wuhan-1 spike [S]; iNCOVACC®) that is currently used in India as a primary or booster immunization. Here, we updated the muc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4feaa7ebcb1e93aae8f29179bab87c2
https://doi.org/10.1101/2023.05.04.539332
https://doi.org/10.1101/2023.05.04.539332
Autor:
James Brett Case, Suzanne M. Scheaffer, Tamarand L. Darling, Traci L. Bricker, Lucas J. Adams, Houda Harastani, Reed Trende, Shilpa Sanapala, Daved H. Fremont, Adrianus C. M. Boon, Michael S. Diamond
Publikováno v:
bioRxiv
The continued evolution and emergence of novel SARS-CoV-2 variants has resulted in challenges to vaccine and antibody efficacy. The emergence of each new variant necessitates the need to re-evaluate and refine animal models used for countermeasure te
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fd2d0b8697e2814673834fd8a1711b9
https://doi.org/10.1101/2023.04.28.538747
https://doi.org/10.1101/2023.04.28.538747
Autor:
Hongbing Jiang, Astha Joshi, Tianyu Gan, Andrew B. Janowski, Chika Fujii, Traci L. Bricker, Tamarand L. Darling, Houda H. Harastani, Kuljeet Seehra, Hongwei Chen, Stephen Tahan, Ana Jung, Binita Febles, Joshua A. Blatter, Scott A. Handley, Bijal A. Parikh, David Wang, Adrianus C. M. Boon
Publikováno v:
bioRxiv
The stem-loop II motif (s2m) is a RNA structural element that is found in the 3’ untranslated region (UTR) of many RNA viruses including severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Though the motif was discovered over twenty-five
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3029f38f116cef9747827e4faa14beaf
https://doi.org/10.1101/2023.03.15.532878
https://doi.org/10.1101/2023.03.15.532878
Autor:
Leon du Toit, Ananya Gupta, Hakim-Moulay Dehbi, Tamarand L. Darling, Darya V. Urusova, Shyamala Thirunavukkarasu, Adrianus C.M. Boon, Erik R. Dubberke, Linda Yun, Sherry McKinnon, Anne K. DeSchryver, Ben Swan, Mihai G. Netea, Shabaana Khader, Michael S. Avidan
Vaccination elicits a complex combination of immune responses. Immune memory formation is observed not only in the antibody responses of B-cells, but also in the T-cell response. Moreover, some live attenuated vaccines such as measles-containing vacc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2dee64a70487c9aac3584b62c40e97e0
https://doi.org/10.1101/2022.09.09.22279771
https://doi.org/10.1101/2022.09.09.22279771