Mitochondrial biogenesis in developing astrocytes regulates astrocyte maturation and synapse formation

Autor: Tamara Zehnder, Francesco Petrelli, Jennifer Romanos, Eva C. De Oliveira Figueiredo, Tommy L. Lewis, Jr., Nicole Déglon, Franck Polleux, Mirko Santello, Paola Bezzi

Publikováno v: Cell Reports, Vol 35, Iss 2, Pp 108952- (2021)

Summary: The mechanisms controlling the post-natal maturation of astrocytes play a crucial role in ensuring correct synaptogenesis. We show that mitochondrial biogenesis in developing astrocytes is necessary for coordinating post-natal astrocyte matu

Externí odkaz: https://doaj.org/article/f1df3debacce4887983091ca5960c352

Astrocytic VMAT2 in the developing prefrontal cortex is required for normal grooming behavior in mice

Autor: Bianca Maria Bondiolotti, P. Bezzi, Nicole Déglon, Alicia Molinero Perez, Luca Pucci, Corrado Calì, Francesco Petrelli, Jean-Pierre Mothet, Tamara Zehnder, Glenn Dallérac, Lorenzo Magrassi, Bruno Giros, Fulvio Magara, Linda D. Simmler

Astrocytes control synaptic activity by modulating peri-synaptic concentrations of ion and neurotransmitters including dopamine and, as such, can be critically involved in the modulation of some aspect of mammalian behavior. Here we report that genet

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b39536dfa82d09a1d1e850400c824eb
https://hal.science/hal-03438361

Dysfunction of homeostatic control of dopamine by astrocytes in the developing prefrontal cortex leads to cognitive impairments

Autor: Corrado Calì, Tamara Zehnder, Graham Knott, Sébastien Sultan, Luca Pucci, Cedric S. Asensio, Robert H. Edwards, Paola Bezzi, Nicole Déglon, Francesco Petrelli, Andrei Ivanov, Glenn Dallérac, Vidar Gundersen, Andrea Chicca, Jürg Gertsch, Nicolas Toni, Jean-Pierre Mothet, Salvatore Lecca, Frank Kirchhoff, Bruno Giros, Fulvio Magara

Publikováno v: Petrelli, Francesco; Dallérac, Glenn; Pucci, Luca; Calì, Corrado; Zehnder, Tamara; Sultan, Sébastien; Lecca, Salvatore; Chicca, Andrea; Ivanov, Andrei; Asensio, Cédric S; Gundersen, Vidar; Toni, Nicolas; Knott, Graham William; Magara, Fulvio; Gertsch, Jürg; Kirchhoff, Frank; Déglon, Nicole; Giros, Bruno; Edwards, Robert H; Mothet, Jean-Pierre; ... (2020). Dysfunction of homeostatic control of dopamine by astrocytes in the developing prefrontal cortex leads to cognitive impairments. Molecular psychiatry, 25(4), pp. 732-749. Nature Publishing Group 10.1038/s41380-018-0226-y
Molecular Psychiatry
Molecular Psychiatry, Nature Publishing Group, 2020, 25 (4), pp.732-749. ⟨10.1038/s41380-018-0226-y⟩
Molecular Psychiatry, 2020, 25 (4), pp.732-749. ⟨10.1038/s41380-018-0226-y⟩
Molecular Psychiatry, Nature Publishing Group, 2018, ⟨10.1038/s41380-018-0226-y⟩
Molecular psychiatry, vol. 25, no. 4, pp. 732-749

International audience; Astrocytes orchestrate neural development by powerfully coordinating synapse formation and function and, as such, may be critically involved in the pathogenesis of neurodevelopmental abnormalities and cognitive deficits common

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8c0e4252e49c07842257473d27cabc9
https://boris.unibe.ch/125028/1/Dysfunction.pdf

Role of Astrocyte Dysfunctions in 22q11 Deletion Syndrome

Autor: Claudia Bagni, Franck Polleux, Tamara Zehnder, Anthony Laugeray, Manuel Mameli, Paola Bezzi, Daniela Rossi

Publikováno v: Biological Psychiatry. 87:S112

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d07c88a57ce0bd9326f0fb8a2f0f75e7
https://doi.org/10.1016/j.biopsych.2020.02.307

Brain natriuretic peptide is able to stimulate cardiac progenitor cell proliferation and differentiation in murine hearts after birth

Autor: Feng Li, Lucas Liaudet, Nathalie Rosenblatt-Velin, Bernard Waeber, Tamara Zehnder, Stéphanie Rignault-Clerc, François Feihl, Christelle Bielmann, Tetsuo Kunieda, Chizuru Sogawa

Publikováno v: Basic research in cardiology. 110(1)

Brain natriuretic peptide (BNP) contributes to heart formation during embryogenesis. After birth, despite a high number of studies aimed at understanding by which mechanism(s) BNP reduces myocardial ischemic injury in animal models, the actual role o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0aec54bdbf799a77bd1aa7bb5041a359
https://pubmed.ncbi.nlm.nih.gov/25449896