Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Tamara Y. Lopez‐Vidal"'
Autor:
Marina Baretti, Adrian G. Murphy, Marianna Zahurak, Nicole Gianino, Rose Parkinson, Rosalind Walker, Tamara Y. Lopez-Vidal, Lei Zheng, Gary Rosner, Nita Ahuja, Schalper Kurt, Nilofer S. Azad
Publikováno v:
Clinical Epigenetics, Vol 15, Iss 1, Pp 1-16 (2023)
Abstract Background Approximately 95% of advanced colorectal cancer patients (CRC) have mismatch repair MMR-proficient (MMRp) tumors, which do not respond to PD1 blockade alone. Preclinical studies have shown that combined histone deacetylases (HDAC)
Externí odkaz:
https://doaj.org/article/54d8bce8d548488f940ee627fd83b2ce
Autor:
Daniel Delitto, Daniel J. Zabransky, Fangluo Chen, Elizabeth D. Thompson, Jacquelyn W. Zimmerman, Todd D. Armstrong, James M. Leatherman, Reecha Suri, Tamara Y. Lopez-Vidal, Amanda L. Huff, Melissa R. Lyman, Samantha R. Guinn, Marina Baretti, Luciane T. Kagohara, Won Jin Ho, Nilofer S. Azad, William R. Burns, Jin He, Christopher L. Wolfgang, Richard A. Burkhart, Lei Zheng, Mark Yarchoan, Neeha Zaidi, Elizabeth M. Jaffee
Publikováno v:
OncoImmunology, Vol 10, Iss 1 (2021)
Tumor involvement of major vascular structures limits surgical options in pancreatic adenocarcinoma (PDAC), which in turn limits opportunities for cure. Despite advances in locoregional approaches, there is currently no role for incomplete resection.
Externí odkaz:
https://doaj.org/article/97094383247048c2ade5ce77d37edcab
Autor:
Theron Palmer, Michael D Kessler, Xiaoshan M. Shao, Archana Balan, Mark Yarchoan, Neeha Zaidi, Tamara Y Lopez-Vidal, Ali Saeed, Jessica Gore, Nilofer S Azad, Elizabeth M Jaffee, Alexander V Favorov, Valsamo Anagnostou, Rachel Karchin, Daria A Gaykalova, Ludmila Danilova, Elana J Fertig
Aberrant alternative splicing can generate neoantigens, which can themselves stimulate immune responses and surveillance. Previous methods for quantifying splicing-derived neoantigens are limited by independent references and potential batch effects.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e15c812249ef96cf0455937244f13725
https://doi.org/10.1101/2023.05.26.542165
https://doi.org/10.1101/2023.05.26.542165
Autor:
Daniel J. Zabransky, Ludmila Danilova, James M. Leatherman, Tamara Y. Lopez‐Vidal, Jessica Sanchez, Soren Charmsaz, Nicole E. Gross, Sarah Shin, Xuan Yuan, Alexei Hernandez, Hongqui Yang, Stephanie Xavier, Daniel Shu, Ali Saeed, Kabeer Munjal, Zeal Kamdar, Luciane T. Kagohara, Elizabeth M. Jaffee, Mark Yarchoan, Won Jin Ho
Publikováno v:
Hepatology
BACKGROUND AND AIMS: The treatment of hepatocellular carcinoma (HCC) has been transformed by the use of immune checkpoint inhibitors. However, most patients with HCC do not benefit from treatment with immunotherapy. There is an urgent need to underst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb8d8e5bded14d7bc88afdbe64239061
https://europepmc.org/articles/PMC9905363/
https://europepmc.org/articles/PMC9905363/
Autor:
Thatcher R. Heumann, Marina Baretti, Elizabeth A. Sugar, Jennifer N. Durham, Sheila Linden, Tamara Y. Lopez-Vidal, James Leatherman, Leslie Cope, Anup Sharma, Colin D. Weekes, Peter J. O’Dwyer, Kim A. Reiss, Dulabh K. Monga, Nita Ahuja, Nilofer S. Azad
Publikováno v:
Clinical Epigenetics. 14
BackgroundOf the only 20% of patients with resectable pancreatic ductal adenocarcinoma (rPDA), cancer recurs in 80% of cases. Epigenetic dysregulation is an early hallmark of cancer cells acquiring metastatic potential, and epigenetic modulators may