Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Tamara Suprunenko"'
Autor:
Alanna G. Spiteri, Tamara Suprunenko, Erin Cutts, Andrew Suen, Thomas M. Ashhurst, Barney Viengkhou, Nicholas J. C. King, Markus J. Hofer
Publikováno v:
Viruses, Vol 16, Iss 3, p 390 (2024)
CD8+ T cells are critical to the adaptive immune response against viral pathogens. However, overwhelming antigen exposure can result in their exhaustion, characterised by reduced effector function, failure to clear virus, and the upregulation of inhi
Externí odkaz:
https://doaj.org/article/26022dd0865c4e828fc5dc8f2712d9fb
Autor:
Tamara Suprunenko, Markus J. Hofer
Publikováno v:
Viruses, Vol 11, Iss 2, p 172 (2019)
Over the past decades, infection of mice with lymphocytic choriomeningitis virus (LCMV) has provided an invaluable insight into our understanding of immune responses to viruses. In particular, this model has clarified the central roles that type I in
Externí odkaz:
https://doaj.org/article/69c3be8a69e8437d808ea57d7262eba1
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 201(7)
Anti-CD4 or anti-CD8α Ab–mediated depletion strategies are widely used to determine the role of T cell subsets. However, surface expression of CD4 and CD8α is not limited to T cells and occurs on other leukocyte populations as well. Using both un
Autor:
Magdalena, Huber, Tamara, Suprunenko, Thomas, Ashhurst, Felix, Marbach, Hartmann, Raifer, Svenja, Wolff, Thomas, Strecker, Barney, Viengkhou, So Ri, Jung, Hannah-Lena, Obermann, Stefan, Bauer, Haifeng C, Xu, Philipp A, Lang, Adomati, Tom, Karl S, Lang, Nicholas J C, King, Iain L, Campbell, Markus J, Hofer
Publikováno v:
Journal of virology. 91(22)
Effective CD8+ T cell responses play an important role in determining the course of a viral infection. Overwhelming antigen exposure can result in suboptimal CD8+ T cell responses, leading to chronic infection. This altered CD8+ T cell differentiatio
Autor:
Hartmann Raifer, Felix Marbach, Haifeng C. Xu, Hannah-Lena Obermann, Svenja Wolff, Philipp A. Lang, Tamara Suprunenko, Barney Viengkhou, Nicholas J. C. King, Thomas M. Ashhurst, Magdalena Huber, So Ri Jung, Adomati Tom, Karl S. Lang, Stefan Bauer, Iain L. Campbell, Markus J. Hofer, Thomas Strecker
Effective CD8 + T cell responses play an important role in determining the course of a viral infection. Overwhelming antigen exposure can result in suboptimal CD8 + T cell responses, leading to chronic infection. This altered CD8 + T cell differentia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55b25c47dee9f27c2555b5d2156a405f
https://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&origin=inward&scp=85032289917
https://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&origin=inward&scp=85032289917
Autor:
Markus J. Hofer, Tamara Suprunenko
Publikováno v:
Viruses, Vol 11, Iss 2, p 172 (2019)
Viruses
Viruses
Over the past decades, infection of mice with lymphocytic choriomeningitis virus (LCMV) has provided an invaluable insight into our understanding of immune responses to viruses. In particular, this model has clarified the central roles that type I in
Autor:
Tamara Suprunenko, Markus J. Hofer
Publikováno v:
Cytokinegrowth factor reviews. 29
The host response to viral infections relies on tightly regulated and intricate signaling pathways involving type I interferons (IFN-Is). The IFN-Is mediate their antiviral effects predominantly through a signaling factor complex that comprises the t
Publikováno v:
Cytokine. 76:73-74
Functional type I interferon (IFN-I) signalling is critical for the host response to viruses. Cellular responses to IFN-Is depend largely on STAT1, STAT2 and IRF9. Here we studied the effects of IRF9 deficiency on the host response to a viral infecti