Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Tamara Sirey"'
Autor:
Andrew J. Finch, Wilfried Haerty, Nick Li, Tamara Sirey, Sebastian Rogatti-Granados, Jimi Wills, Oscar C. Bedoya-Reina, Sarah Cooper, Kenny Roberts, Jennifer Y. Tan, Chris P. Ponting, Ana C. Marques, Nicholas M. Morton, Roderick N. Carter, Lisa C. Heather
Publikováno v:
eLife, vol. 8, pp. e45051
eLife
eLife, Vol 8 (2019)
Sirey, T M, Roberts, K, Haerty, W, Bedoya-Reina, O, Rogatti-Granados, S, Tan, J Y, Li, N, Heather, L C, Carter, R N, Cooper, S, Finch, A J, Wills, J, Morton, N M, Marques, A C & Ponting, C P 2019, ' The long non-coding RNA Cerox1 is a post transcriptional regulator of mitochondrial complex I catalytic activity ', eLIFE, vol. 8, e45051 . https://doi.org/10.7554/eLife.45051
eLife
eLife, Vol 8 (2019)
Sirey, T M, Roberts, K, Haerty, W, Bedoya-Reina, O, Rogatti-Granados, S, Tan, J Y, Li, N, Heather, L C, Carter, R N, Cooper, S, Finch, A J, Wills, J, Morton, N M, Marques, A C & Ponting, C P 2019, ' The long non-coding RNA Cerox1 is a post transcriptional regulator of mitochondrial complex I catalytic activity ', eLIFE, vol. 8, e45051 . https://doi.org/10.7554/eLife.45051
To generate energy efficiently, the cell is uniquely challenged to co-ordinate the abundance of electron transport chain protein subunits expressed from both nuclear and mitochondrial genomes. How an effective stoichiometry of this many constituent s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c98d9870d3274ce0e32b4190c3ef7cd5
https://doi.org/10.7554/elife.45051
https://doi.org/10.7554/elife.45051
Autor:
Ana C. Marques, Wilfried Haerty, Tamara Sirey, Nick Li, Chris P. Ponting, Kenny Roberts, Rogatti-Granados S, Cooper S, Jennifer Y. Tan, Oscar C. Bedoya-Reina, Lisa C. Heather
To generate energy efficiently, the cell is uniquely challenged to co-ordinate the abundance of electron transport chain protein subunits expressed from both nuclear and mitochondrial genomes. How an effective stoichiometry of this many constituent s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b68c6d02308c3e15137d8d4a57a7ad19
https://doi.org/10.1101/323907
https://doi.org/10.1101/323907
Autor:
Sang Hoon Lee, Ioanna Pavlaki, Bin Sun, Dan J. Woodcock, Keith W. Vance, Tamara Sirey, Farah Alammari, Francis G. Szele, Chris P. Ponting, Neil Clark
Publikováno v:
Pavlaki, I, Alammari, F, Sun, B, Clark, N, Sirey, T, Lee, S, Woodcock, D J, Ponting, C, Szele, F & Vance, K W 2018, ' The long non-coding RNA Paupar promotes KAP1-dependent chromatin changes and regulates olfactory bulb neurogenesis ', EMBO Journal . https://doi.org/10.15252/embj.201798219
Many long non‐coding RNAs (lncRNAs) are expressed during central nervous system (CNS) development, yet their in vivo roles and mechanisms of action remain poorly understood. Paupar , a CNS‐expressed lncRNA, controls neuroblastoma cell growth by b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e26c7bf3796ea05e20609e7c22b2ad0
https://doi.org/10.15252/embj.201798219
https://doi.org/10.15252/embj.201798219
Publikováno v:
Critical Reviews in Biochemistry and Molecular Biology
Control of gene and protein expression is required for cellular homeostasis and is disrupted in disease. Following transcription, mRNA turnover and translation is modulated, most notably by microRNAs (miRNAs). This modulation is controlled by transcr
Autor:
Tamara Sirey, Ana C. Marques, Chris P. Ponting, Matthias Merkenschlager, Caleb Webber, Bryony Graham, Frantisek Honti, Jennifer Y. Tan, Allison Piovesan
Publikováno v:
Genome Research
Genome Research, vol. 25, no. 5, pp. 655-666
Genome Research, vol. 25, no. 5, pp. 655-666
Recently, a handful of intergenic long noncoding RNAs (lncRNAs) have been shown to compete with mRNAs for binding to miRNAs and to contribute to development and disease. Beyond these reports, little is yet known of the extent and functional consequen
Autor:
Ioanna, Pavlaki, Farah, Alammari, Bin, Sun, Neil, Clark, Tamara, Sirey, Sheena, Lee, Dan J, Woodcock, Chris P, Ponting, Francis G, Szele, Keith W, Vance
Publikováno v:
The EMBO Journal
Many long non‐coding RNAs (lncRNAs) are expressed during central nervous system (CNS) development, yet their in vivo roles and mechanisms of action remain poorly understood. Paupar, a CNS‐expressed lncRNA, controls neuroblastoma cell growth by bi
Autor:
Dan J. Woodcock, Keith W. Vance, Tamara Sirey, Farah Alammari, Francis G. Szele, Ioanna Pavlaki, Bin Sun, Chris P. Ponting, Neil Clark, Sang Hoon Lee
Many long non-coding RNAs (lncRNAs) are expressed during central nervous system (CNS) development, yet theirin vivoroles and molecular mechanisms of action remain poorly understood.Paupar, a CNS expressed lncRNA, controls neuroblastoma cell growth by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcd808264f2cfd4e8712d60587f00098
https://doi.org/10.1101/187302
https://doi.org/10.1101/187302
Autor:
Tamara Sirey, Chris P. Ponting
Publikováno v:
Sirey, T & Ponting, C 2016, ' Insights into the post-transcriptional regulation of the mitochondrial electron transport chain ', Biochemical Society Transactions . https://doi.org/10.1042/BST20160100
Biochemical Society Transactions
Biochemical Society Transactions
The regulation of the mitochondrial electron transport chain is central to the control of cellular homeostasis. There are significant gaps in our understanding of how the expression of the mitochondrial and nuclear genome-encoded components of the el
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19110258834713c17168ca6ee45f17c2
https://hdl.handle.net/20.500.11820/01726079-31cc-4e0c-bd3e-d69d1a5f3eb9
https://hdl.handle.net/20.500.11820/01726079-31cc-4e0c-bd3e-d69d1a5f3eb9
Autor:
Peter L. Oliver, Jennifer Y. Tan, Sarah Cooper, Tatyana B. Nesterova, Annie Sittler, Matthew J.A. Wood, Martina Marinello, Ana C. Marques, Tamara Sirey, Bruno R. Steinkraus, Lauren M Watson, Miguel A. Varela, Keith W. Vance, Chris P. Ponting, Sandro Alves, Helen J Curtis, Neil Brockdorff, Alexis Brice, Tudor A. Fulga
Publikováno v:
Nature structural & molecular biology
What causes the tissue-specific pathology of diseases resulting from mutations in housekeeping genes? Specifically, in spinocerebellar ataxia type 7 (SCA7), a neurodegenerative disorder caused by a CAG-repeat expansion in ATXN7 (which encodes an esse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a5bcb86d771811e8ccc60b1e4d90185
https://ora.ox.ac.uk/objects/uuid:b5af8214-94b5-44c2-9763-cc9de1016c3e
https://ora.ox.ac.uk/objects/uuid:b5af8214-94b5-44c2-9763-cc9de1016c3e
Publikováno v:
Journal of Anatomy. 218:349-361