Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Tamara Roitbak"'
Autor:
Juan Carlos Pena‐Philippides, Amy Sabrina Gardiner, Ernesto Caballero‐Garrido, Rong Pan, Yiliang Zhu, Tamara Roitbak
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 7, Iss 13 (2018)
Background Brain microvascular endothelial cells form a highly selective blood brain barrier regulated by the endothelial tight junctions. Cerebral ischemia selectively targets tight junction protein complexes, which leads to significant damage to ce
Externí odkaz:
https://doaj.org/article/4198973b22b3475c8ac73ba80928a1d3
Autor:
Tamara Roitbak
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 11 (2018)
Stroke-induced endothelial cell injury leads to destruction of cerebral microvasculature and significant damage to the brain tissue. A subacute phase of cerebral ischemia is associated with regeneration involving the activation of vascular remodeling
Externí odkaz:
https://doaj.org/article/95a3f08e6fd54ecca030db644b996403
Autor:
Tamara Roitbak, Andrew P. Carlson, Ron L. Mims, Karen S. SantaCruz, Howard Yonas, Jeremy S. Edwards, William H McKay, Radha Swaminathan
Publikováno v:
Genes
Genes, Vol 12, Iss 1860, p 1860 (2021)
Genes; Volume 12; Issue 12; Pages: 1860
Genes, Vol 12, Iss 1860, p 1860 (2021)
Genes; Volume 12; Issue 12; Pages: 1860
Background: Signaling pathways mediated by microRNAs (miRNAs) have been identified as one of the mechanisms that regulate stroke progression and recovery. Recent investigations using stroke patient blood and cerebrospinal fluid (CSF) demonstrated dis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a34d353021ba32dba0fb05f22729a79b
http://europepmc.org/articles/PMC8702168
http://europepmc.org/articles/PMC8702168
Autor:
Tamara Roitbak
Publikováno v:
Neurochem Res
microRNAs (miRNAs) are recently identified small RNA molecules that regulate gene expression and significantly influence the essential cellular processes associated with CNS repair after trauma and neuropathological conditions including stroke and ne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d90a9a65f5b9cb617873b9c9305e951
https://pubmed.ncbi.nlm.nih.gov/30877519
https://pubmed.ncbi.nlm.nih.gov/30877519
Autor:
Tamara Roitbak, Juan Carlos Pena-Philippides, Rong Pan, Amy S. Gardiner, Yiliang Zhu, Ernesto Caballero-Garrido
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Brain microvascular endothelial cells form a highly selective blood brain barrier regulated by the endothelial tight junctions. Cerebral ischemia selectively targets tight junction protein complexes, which leads to significant damage to ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c316d14f0b65d24d2710c585d12703f5
https://doi.org/10.1161/jaha.118.009244
https://doi.org/10.1161/jaha.118.009244
Autor:
Erik B. Erhardt, Tamar Lordkipanidze, Juan Carlos Pena-Philippides, Yirong Yang, Tamara Roitbak, Denis E. Bragin, Ernesto Caballero-Garrido
Publikováno v:
Journal of Neuroscience. 35:12446-12464
A multifunctional microRNA, miR-155, has been recently recognized as an important modulator of numerous biological processes. In our previous in vitro studies, miR-155 was identified as a potential regulator of the endothelial morphogenesis. The pres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc974e86c9514ff17780787849102c3c
https://doi.org/10.1523/jneurosci.1641-15.2015
https://doi.org/10.1523/jneurosci.1641-15.2015
Autor:
Erik B. Erhardt, Juan Carlos Pena-Philippides, Tamara Roitbak, Z. Galochkina, Ernesto Caballero-Garrido
Evaluation of functional outcome is widely used across species to assess the recovery process following various pathological conditions, including spinal cord injury, musculo-skeletal injury, mithochondrial disease, neuropathic cancer, Huntington's d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c46fc03fd8012234f9bdedeabc3a5125
https://europepmc.org/articles/PMC5543803/
https://europepmc.org/articles/PMC5543803/
Publikováno v:
Journal of Neuroinflammation
Background MicroRNA miR-155 is implicated in modulation of the inflammatory processes in various pathological conditions. In our previous studies, we demonstrated that in vivo inhibition of miR-155 promotes functional recovery after mouse experimenta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::262352442e58e43512f4ef2150e92aba
https://doi.org/10.1186/s12974-016-0753-x
https://doi.org/10.1186/s12974-016-0753-x
Autor:
Patricia D. Wilson, Richard Sandford, Ruth L. Case, Xiaohong Li, Catherine A. Boucher, Angela Wandinger-Ness, Heather H. Ward, Christopher J. Ward, Katie S. Thurston, Tamara Roitbak, Andrew Needham, Deborah Hyink, Seema Qamar, Samantha Powell, Elsa Romero
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1812:1225-1238
Autosomal dominant polycystic kidney disease (ADPKD) is caused by mutation of PKD1 and PKD2 that encode polycystin-1 and polycystin-2. Polycystin-1 is tyrosine phosphorylated and modulates multiple signaling pathways including AP-1, and the identity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6d2c42adb69d1fecffc3a3ad3e4332c
https://doi.org/10.1016/j.bbadis.2010.11.006
https://doi.org/10.1016/j.bbadis.2010.11.006
Autor:
Vincent H. Gattone, Heather H. Ward, Robert L. Bacallao, Gavin Pickett, Angela Welford, Elsa Romero, Scott A. Ness, Angela Wandinger-Ness, Tamara Roitbak
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1812:1344-1357
Approximately 60,000 patients in the United States are waiting for a kidney transplant due to genetic, immunologic and environmentally caused kidney failure. Adult human renal stem cells could offer opportunities for autologous transplant and repair
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::185640b72f02e03ca68d387359854283
https://doi.org/10.1016/j.bbadis.2011.01.010
https://doi.org/10.1016/j.bbadis.2011.01.010