Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Tamara R. McInnis"'
Autor:
Ella A. Kasanga, Joel Little, Tamara R. McInnis, Nicoleta Bugnariu, J. Thomas Cunningham, Michael F. Salvatore
Publikováno v:
Frontiers in Aging Neuroscience, Vol 13 (2021)
Preservation of motor capabilities is vital to maintaining independent daily living throughout a person's lifespan and may mitigate aging-related parkinsonism, a progressive and prevalent motor impairment. Physically active lifestyles can mitigate ag
Externí odkaz:
https://doaj.org/article/2a4eb8df6edc459f9e6d2985d1a77e0f
Autor:
Michael F. Salvatore, Ella A. Kasanga, D. Parker Kelley, Katy E. Venable, Tamara R. McInnis, Mark A. Cantu, Jennifer Terrebonne, Kathryn Lanza, Samantha M. Meadows, Ashley Centner, Christopher Bishop, Donald K. Ingram
Publikováno v:
GeroScience
Identifying neurobiological mechanisms of aging-related parkinsonism, and lifestyle interventions that mitigate them, remain critical knowledge gaps. No aging study, from rodent to human, has reported loss of any dopamine (DA) signaling marker near t
Autor:
Michelle Taylor, Nathalie Sumien, Tamara R McInnis, Boeun Lee, Suzy A. Griffin, Robert R. Luedtke, Robert H. Mach
Publikováno v:
Molecules, Vol 26, Iss 3182, p 3182 (2021)
Molecules
Volume 26
Issue 11
Molecules
Volume 26
Issue 11
N-phenylpiperazine analogs can bind selectively to the D3 versus the D2 dopamine receptor subtype despite the fact that these two D2-like dopamine receptor subtypes exhibit substantial amino acid sequence homology. The binding for a number of these r
Ceftriaxone reducesL -dopa-induced dyskinesia severity in 6-hydroxydopamine parkinson's disease model
Autor:
Tanya Chotibut, Ella A. Kasanga, Michael F. Salvatore, Tamara R McInnis, Christopher Bishop, Samantha M. Meadows, Mark A. Cantu
Publikováno v:
Movement Disorders. 32:1547-1556
Background: Increased extracellular glutamate may contribute to l-dopa induced dyskinesia, a debilitating side effect faced by Parkinson's disease patients 5 to 10 years after l-dopa treatment. Therapeutic strategies targeting postsynaptic glutamate
Publikováno v:
Molecular neurobiology. 56(4)
Reduced movement frequency or physical activity (bradykinesia) occurs with high prevalence in the elderly. However, loss of striatal tyrosine hydroxylase (TH) in aging humans, non-human primates, or rodents does not reach the ~80% loss threshold asso
Autor:
Parker Kelley, Catherine L. Owens, Katy Venable, Jennifer Terrebonne, Tamara R McInnis, Brandon S. Pruett, Ella A. Kasanga, Brian Latimer, Donald K. Ingram, Yongmei Yu, Nathalie Sumien, Michael F. Salvatore, Michael J. Forster, Robert R. Luedtke, Mark A. Cantu
Publikováno v:
The journals of gerontology. Series A, Biological sciences and medical sciences. 73(1)
The escalating increase in retirees living beyond their eighth decade brings increased prevalence of aging-related impairments, including locomotor impairment (Parkinsonism) that may affect ~50% of those reaching age 80, but has no confirmed neurobio