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Legionella pneumophila S1P-lyase targets host sphingolipid metabolism and restrains autophagy

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2016, 113 (7), pp.1901-1906. ⟨10.1073/pnas.1522067113⟩
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2016, 113 (7), pp.1901-1906. 〈10.1073/pnas.1522067113〉
Proceedings of the National Academy of Sciences of the United States of America, 2016, 113 (7), pp.1901-1906. ⟨10.1073/pnas.1522067113⟩

International audience; Autophagy is an essential component of innate immunity, enabling the detection and elimination of intracellular pathogens. Legionella pneumophila, an intracellular pathogen that can cause a severe pneumonia in humans, is able

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71c5a2731c9c1fa967be8515cfee067a
https://doi.org/10.1073/pnas.1522067113

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The Legionella pneumophila F-box protein Lpp2082 (AnkB) modulates ubiquitination of the host protein parvin B and promotes intracellular replication

Autor: Laura Gomez-Valero, Elizabeth L. Hartland, Mariella Lomma, Fiona M. Sansom, Tobias Sahr, Tamara Nora, Delphine Dervins-Ravault, Monica Rolando, Carmen Buchrieser, Hayley J. Newton, Matthieu Jules

Publikováno v: Cellular Microbiology. 12:1272-1291

The environmental pathogen Legionella pneumophila encodes three proteins containing F-box domains and additional protein-protein interaction domains, reminiscent of eukaryotic SCF ubiquitin-protein ligases. Here we show that the F-box proteins of L.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8ca27c6e982e4ddd172050acc246f50d
https://doi.org/10.1111/j.1462-5822.2010.01467.x

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Extensive Recombination among Human Immunodeficiency Virus Type 1 Quasispecies Makes an Important Contribution to Viral Diversity in Individual Patients

Autor: François Clavel, Olivier Tenaillon, Allan J. Hance, Tamara Nora, Charlotte Charpentier

Publikováno v: Journal of Virology. 80:2472-2482

Although recombination during human immunodeficiency virus type 1 (HIV-1) replication in vitro and in vivo has been documented, little information is available concerning the extent that recombination contributes to the diversity of HIV-1 quasispecie

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::266642ef21cf517b1c7aef0b1ad1d8a5
https://doi.org/10.1128/jvi.80.5.2472-2482.2006

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Molecular mimicry: an important virulence strategy employed by Legionella pneumophila to subvert host functions

Autor: Mariella Lomma, Laura Gomez-Valero, Carmen Buchrieser, Tamara Nora

Publikováno v: Future microbiology. 4(6)

It is 32 years since Legionella pneumophila was identified and recognized as a human pathogen, causing the severe form of pneumonia termed Legionnaires’ disease, or legionellosis. This bacterium is found in freshwater reservoirs where it replicates

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c297dc6d67c19fc06fc216b4a24f8380
https://pubmed.ncbi.nlm.nih.gov/19659425

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Contribution of Recombination to the Evolution of Human Immunodeficiency Viruses Expressing Resistance to Antiretroviral Treatment▿

Autor: Olivier Tenaillon, Allan J. Hance, Charlotte Charpentier, Tamara Nora, Claire Hoede, François Clavel

Publikováno v: Journal of Virology
Journal of Virology, American Society for Microbiology, 2007, 81 (14), pp.7620-7628. ⟨10.1128/JVI.00083-07⟩

Viral recombination has been postulated to play two roles in the development of human immunodeficiency virus (HIV) resistance to antiretroviral drugs. First, recombination has the capacity to associate resistance mutations expressed by distinct virus

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18d71a6777dc5f5728da9db77af4f626
https://europepmc.org/articles/PMC1933369/

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Functional diversity of HIV-1 envelope proteins expressed by contemporaneous plasma viruses

Autor: Béatrice Labrosse, François Clavel, Charlotte Charpentier, Tamara Nora, Allan J. Hance, Fabrizio Mammano, Francine Bouchonnet

Publikováno v: Retrovirology
Retrovirology, Vol 5, Iss 1, p 23 (2008)

BackgroundNumerous studies have shown that viral quasi-species with genetically diverse envelope proteins (Env) replicate simultaneously in patients infected with the human immunodeficiency virus type 1 (HIV-1). Less information is available concerni

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b45e237755f2e8d2aff6b21a770bca1
http://europepmc.org/articles/PMC2270869

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