Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Tamara N. Steinhauer"'
Autor:
Inken Flörkemeier, Tamara N. Steinhauer, Nina Hedemann, Magnus Ölander, Per Artursson, Bernd Clement, Dirk O. Bauerschlag
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 13 (2021)
Background: Ovarian cancer (OvCa) constitutes a rare and highly aggressive malignancy and is one of the most lethal of all gynaecologic neoplasms. Due to chemotherapy resistance and treatment limitations because of side effects, OvCa is still not suf
Externí odkaz:
https://doaj.org/article/8b89334405764c299bc1e0e335c0f7dc
Autor:
Georg Aichinger, Falk-Bach Lichtenberger, Tamara N. Steinhauer, Inken Flörkemeier, Giorgia Del Favero, Bernd Clement, Doris Marko
Publikováno v:
Molecules, Vol 25, Iss 7, p 1524 (2020)
The benzo[c]phenanthridine P8-D6 was recently found to suppress the catalytic activity of both human topoisomerase (Topo) I and II. Concomitantly, potent cytotoxic activity was observed in different human tumor cell lines, raising questions about the
Externí odkaz:
https://doaj.org/article/1d43c6f252b94497974bda9b2f236fd9
Autor:
Bernd Clement, Per Artursson, Dirk Bauerschlag, Magnus Ölander, Tamara N. Steinhauer, Nina Hedemann, Inken Flörkemeier
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 13 (2021)
Therapeutic Advances in Medical Oncology
Therapeutic Advances in Medical Oncology
Background: Ovarian cancer (OvCa) constitutes a rare and highly aggressive malignancy and is one of the most lethal of all gynaecologic neoplasms. Due to chemotherapy resistance and treatment limitations because of side effects, OvCa is still not suf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f9cace114206af7cc44e391575cec9c
https://doi.org/10.21203/rs.3.rs-743550/v1
https://doi.org/10.21203/rs.3.rs-743550/v1
Publikováno v:
Geburtshilfe und Frauenheilkunde.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f8a180326fc2bcd21d1157138ae9261
https://doi.org/10.1055/s-0040-1714544
https://doi.org/10.1055/s-0040-1714544
Autor:
Inken Flörkemeier, Tamara N. Steinhauer, Nina Hedemann, Jörg Paul Weimer, Christoph Rogmans, Marion T. van Mackelenbergh, Nicolai Maass, Bernd Clement, Dirk O. Bauerschlag
Publikováno v:
Cancers, Vol 14, Iss 2, p 2 (2022)
Cancers; Volume 14; Issue 1; Pages: 2
Cancers
Cancers; Volume 14; Issue 1; Pages: 2
Cancers
Simple Summary Despite significant advancement in therapeutic strategies, breast cancers remain the most prevalent type of cancer in terms of incidence and mortality worldwide. Therefore, new alternative therapies have become an urgent clinical need.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42d81aeaa1b35cf620dbcbe4e304270b
https://doi.org/10.3390/cancers14010002
https://doi.org/10.3390/cancers14010002
A Dual Topoisomerase Inhibitor of Intense Pro-Apoptotic and Antileukemic Nature for Cancer Treatment
Autor:
Christopher Meier, Fabian Koczian, Angelika M. Vollmar, Birte Plitzko, Katharina Jarolim, Ulrich Girreser, Bernd Clement, Simone Braig, Tamara N. Steinhauer, Doris Marko
Publikováno v:
ChemMedChem. 12:347-352
Classic cytotoxic drugs remain indispensable instruments in antitumor therapy due to their effectiveness and a more prevalent insensitivity toward tumor resistance mechanisms. Herein we describe the favorable properties of 6-(N,N-dimethyl-2-aminoetho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3d81b0586a9b51c28d69ebd2693e795
https://doi.org/10.1002/cmdc.201700026
https://doi.org/10.1002/cmdc.201700026
Autor:
Tamara N. Steinhauer, Inken Flörkemeier, Dirk Bauerschlag, Bernd Clement, MT van Mackelenbergh
Publikováno v:
Senologie - Zeitschrift für Mammadiagnostik und -therapie.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b2955701418d7e2f42e94114d1919e2c
https://doi.org/10.1055/s-0039-1687964
https://doi.org/10.1055/s-0039-1687964
Autor:
Tamara N. Steinhauer, Inga Zebothsen, Dieter Heber, Doris Marko, Matthias Weide, Bernd Clement, Christopher Meier, Dana zur Nieden, Ulrich Wolschendorf, Georg Aichinger, Ulrich Girreser, Ilka Kaltefleiter, Lars Stenzel
Publikováno v:
ChemMedChem. 11:2155-2170
The synthesis of various new structures of a library of 11-substituted 6-amino-11,12-dihydrobenzo[c]phenanthridines (BP) and 11-substituted 6-aminobenzo[c]phenanthridines (BP-D) is presented. These structures, further synthetic modifications, and the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9973aa1ed401d961a0fcd00ad9e855d
https://doi.org/10.1002/cmdc.201600199
https://doi.org/10.1002/cmdc.201600199
Publikováno v:
Chemistry - A European Journal. 22:8301-8308
A versatile one-step two-component cyclization to build new tetracyclic nitrogen heterocycles is described. Ortho-methylhetarenecarbonitrile components were condensed with aldehydes to access a large library of differently substituted ring systems. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b68588b2e07e2f09fc2ac1c3e32260ef
https://doi.org/10.1002/chem.201600308
https://doi.org/10.1002/chem.201600308
Autor:
Inken Flörkemeier, Georg Aichinger, Giorgia Del Favero, Tamara N. Steinhauer, Doris Marko, Bernd Clement, Falk-Bach Lichtenberger
Publikováno v:
Molecules, Vol 25, Iss 1524, p 1524 (2020)
Molecules
Volume 25
Issue 7
Molecules
Volume 25
Issue 7
The benzo[c]phenanthridine P8-D6 was recently found to suppress the catalytic activity of both human topoisomerase (Topo) I and II. Concomitantly, potent cytotoxic activity was observed in different human tumor cell lines, raising questions about the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::096c175234011b74bd281fd4b7be8573
https://doi.org/10.3390/molecules25071524
https://doi.org/10.3390/molecules25071524