Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Tamara Major"'
Autor:
Irena Jovanovic Macura, Desanka Milanovic, Vesna Tesic, Tamara Major, Milka Perovic, Miroslav Adzic, Sanja Ivkovic
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 17, p 9400 (2024)
In patients with Alzheimer’s disease (AD) and in animal models, the increased accumulation of amyloid β (Aβ) in retinal blood vessels strongly correlates with brain amyloid deposits and cognitive decline. The accumulation of Aβ in blood vessels
Externí odkaz:
https://doaj.org/article/61af0afc172644a9b008c988f947af3f
Autor:
Irena Jovanovic Macura, Ivana Djuricic, Tamara Major, Desanka Milanovic, Sladjana Sobajic, Selma Kanazir, Sanja Ivkovic
Publikováno v:
Frontiers in Nutrition, Vol 10 (2024)
IntroductionDuring fetal development, the proper development of neural and visual systems relies on the maternal supplementation of omega-3 fatty acids through placental transfer. Pregnant women are strongly advised to augment their diet with additio
Externí odkaz:
https://doaj.org/article/5f755ce48eb64f64a22ae08150e9323f
Autor:
Jelena Martinovic, Janko Samardzic, Marina Zaric Kontic, Sanja Ivkovic, Sanja Dacic, Tamara Major, Milica Radosavljevic, Dubravka Svob Strac
Publikováno v:
Brain Sciences, Vol 13, Iss 12, p 1707 (2023)
Zaleplon is a positive allosteric modulator of the γ-aminobutyric acid (GABA)A receptor approved for the short-term treatment of insomnia. Previous publications on zaleplon have not addressed the proteins involved in its mechanism of action but have
Externí odkaz:
https://doaj.org/article/43ea03d7d8374e0ca4dab8a675fc1039
Autor:
Irena Jovanovic Macura, Ana Zivanovic, Milka Perovic, Jelena Ciric, Tamara Major, Selma Kanazir, Sanja Ivkovic
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 18, p 14092 (2023)
Cerebral amyloid angiopathy (CAA) is characterized by amyloid β (Aβ) accumulation in the blood vessels and is associated with cognitive impairment in Alzheimer’s disease (AD). The increased accumulation of Aβ is also present in the retinal blood
Externí odkaz:
https://doaj.org/article/a07a75827335476bb5fab7c3d9890eb8
Autor:
Irena Jovanovic Macura, Ivana Djuricic, Tamara Major, Desanka Milanovic, Marjana Brkic, Sladjana Sobajic, Selma Kanazir, Sanja Ivkovic
Publikováno v:
Journal of Functional Foods, Vol 99, Iss , Pp 105302- (2022)
The recommended fish oil (FO) supplementation doses often yield low omega-3 polyunsaturated fatty acids (PUFAs) tissue bioavailability, and higher doses (up to 10 g per day) have been increasingly recommended. However, the exact effects of such FO su
Externí odkaz:
https://doaj.org/article/a262792a02464bfd92429eefe76bfb32
Autor:
Tamara Major, Jayanthi Menon, Gordon Auyeung, Frank Soldner, Dirk Hockemeyer, Rudolf Jaenisch, Viviane Tabar
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e24687 (2011)
The derivation of induced human pluripotent stem cells (hiPS) has generated significant enthusiasm particularly for the prospects of cell-based therapy. But there are concerns about the suitability of iPS cells for in vivo applications due in part to
Externí odkaz:
https://doaj.org/article/b8b4e457255e42d7b4977cf55b5eaa31
Autor:
Sanja Ivkovic, Tamara Major, Milos Mitic, Natasa Loncarevic-Vasiljkovic, Milena Jovic, Miroslav Adzic
Publikováno v:
Life Sciences
The brain is the softest organ in the body, and any change in the mechanical properties of the tissue induces the activation of glial cells, astrocytes and microglia. Amyloid plaques, one of the main pathological features of Alzheimer's disease (AD),
Autor:
Viviane Tabar, Edelweiss Policarpio, Jason Tchieu, Philip H. Gutin, Denis Soulet, Gordon Auyeung, Jinghua Piao, Leif A. Droms, Tamara Major, Jayanthi Menon, Kunihiro Uryu
Publikováno v:
Cell Stem Cell. 16:198-210
SummaryRadiation therapy to the brain is a powerful tool in the management of many cancers, but it is associated with significant and irreversible long-term side effects, including cognitive decline and impairment of motor coordination. Depletion of
Publikováno v:
Science. 346:1529-1533
Over 70% of diffuse intrinsic pediatric gliomas, an aggressive brainstem tumor, harbor heterozygous mutations that create a K27M amino acid substitution (methionine replaces lysine 27) in the tail of histone H3.3. The role of the H3.3K27M mutation in
Publikováno v:
Current Protocols in Stem Cell Biology
Oligodendrocytes are the main myelinating cell of the adult CNS and are vulnerable to injury in diverse disorders such as spinal cord injury, stroke, trauma, pharmacological and radiation toxicity, as well as neuroinflammation. Human pluripotent stem