Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Tamara L. Davis"'
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Differential methylation of imprinting control regions in mammals is essential for distinguishing the parental alleles from each other and regulating their expression accordingly. To ensure parent of origin-specific expression of imprinted genes and
Externí odkaz:
https://doaj.org/article/2757a523ad1d465797b177ffa63172da
Autor:
Julianna Nechin, Emma Tunstall, Naideline Raymond, Nicole Hamagami, Chris Pathmanabhan, Samantha Forestier, Tamara L. Davis
Publikováno v:
Epigenetics & Chromatin, Vol 12, Iss 1, Pp 1-13 (2019)
Abstract Background In mammals, the regulation of imprinted genes is controlled by differential methylation at imprinting control regions which acquire parent of origin-specific methylation patterns during gametogenesis and retain differences in alle
Externí odkaz:
https://doaj.org/article/35c8c5f4891c4780a26b0e6188c3eb11
Publikováno v:
Epigenetics & Chromatin, Vol 10, Iss 1, Pp 1-14 (2017)
Abstract Background Differential DNA methylation plays a critical role in the regulation of imprinted genes. The differentially methylated state of the imprinting control region is inherited via the gametes at fertilization, and is stably maintained
Externí odkaz:
https://doaj.org/article/c0148f803b984cf5a654ad9e94602d80
Publikováno v:
Epigenetics & Chromatin, Vol 10, Iss 1, Pp 1-14 (2017)
Epigenetics & Chromatin
Epigenetics & Chromatin
Background Differential DNA methylation plays a critical role in the regulation of imprinted genes. The differentially methylated state of the imprinting control region is inherited via the gametes at fertilization, and is stably maintained in somati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7551342e3baabc2baab289d2686c117
http://link.springer.com/article/10.1186/s13072-017-0138-0
http://link.springer.com/article/10.1186/s13072-017-0138-0
Autor:
Samantha Forestier, Julianna Nechin, Emma Tunstall, Tamara L. Davis, Naideline Raymond, Nicole Hamagami, Chris Pathmanabhan
Publikováno v:
Epigenetics & Chromatin, Vol 12, Iss 1, Pp 1-13 (2019)
Epigenetics & Chromatin
Epigenetics & Chromatin
Background In mammals, the regulation of imprinted genes is controlled by differential methylation at imprinting control regions which acquire parent of origin-specific methylation patterns during gametogenesis and retain differences in allelic methy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b6c85d81ca82311c3b032fa6b33c472
https://doi.org/10.1186/s13072-019-0309-2
https://doi.org/10.1186/s13072-019-0309-2
Publikováno v:
Genomics. 84:961-970
Monoallelic expression of imprinted genes is generally associated with differential methylation. Methylation may be inherited as the gametic imprinting mark or may be acquired postfertilization. Here, we characterize a differentially methylated regio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ec4f8d1b52484d11bb310634329f99e
https://doi.org/10.1016/j.ygeno.2004.08.004
https://doi.org/10.1016/j.ygeno.2004.08.004
Publikováno v:
Human Molecular Genetics. 9:2885-2894
Differences in DNA methylation distinguish the maternal and paternal alleles of many imprinted genes. Allele-specific methylation that is inherited from the gametes and maintained throughout development has been proposed as a candidate imprinting mar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0f5828a62d19c599962f1f257265b5f
https://doi.org/10.1093/hmg/9.19.2885
https://doi.org/10.1093/hmg/9.19.2885
Publikováno v:
Genomics. 58:18-28
The imprinted mouse H19 gene is hypomethylated on the expressed maternal allele and hypermethylated on the silent paternal allele. A 2-kb region of differential methylation located from -2 to -4 kb relative to the H19 transcriptional start site has b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7687b59f5ecfcca6363b0d4aedc36c2e
https://doi.org/10.1006/geno.1999.5813
https://doi.org/10.1006/geno.1999.5813
Publikováno v:
Developmental Genetics. 23:111-118
The imprinted H19 gene is hypomethylated on the active maternal allele and hypermethylated on the repressed paternal allele in the somatic tissues of mice and humans. We previously demonstrated that the paternal-specific methylation of a 2 kb region
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::84c6730f3b5d7c3a59b49f39fe81eafb
https://doi.org/10.1002/(sici)1520-6408(1998)23:2<111::aid-dvg3>3.0.co
https://doi.org/10.1002/(sici)1520-6408(1998)23:2<111::aid-dvg3>3.0.co
Autor:
Snehal Naik, Lu Mei He, Tamara L. Davis, Kamila Nowak, Jane Morris, Geneva M. Stein, Sara Marlow, Elizabeth Powell
Publikováno v:
Epigenetics. 6(8)
The monoallelic expression of imprinted genes is controlled by epigenetic factors including DNA methylation and histone modifications. In mouse, the imprinted gene Gtl2 is associated with two differentially methylated regions: the IG-DMR, which serve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10de7ecd5e19f1fdbd95adb29e61f3ac
https://pubmed.ncbi.nlm.nih.gov/21725202
https://pubmed.ncbi.nlm.nih.gov/21725202