Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Tamara K Berthoud"'
Publikováno v:
PLoS ONE, Vol 12, Iss 11, p e0186823 (2017)
HIV infection causes a profound depletion of gut derived Th17 cells, contributing to loss of mucosal barrier function and an increase in microbial translocation, thus driving systemic immune activation. Despite normalization of circulating CD4+ T cel
Externí odkaz:
https://doaj.org/article/b14cae65b3ae453db6537a1cbb3a8b8c
Autor:
Timothy J Powell, Yanchun Peng, Tamara K Berthoud, Marie-Eve Blais, Patrick J Lillie, Adrian V S Hill, Sarah L Rowland-Jones, Andrew J McMichael, Sarah C Gilbert, Tao Dong
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e62778 (2013)
Current influenza vaccines stimulate neutralising antibody to the haemagglutinin antigen but as there is antigenic drift in HA it is difficult to prepare a vaccine in advance against an emergent strain. A potential strategy is to induce CD8(+) and CD
Externí odkaz:
https://doaj.org/article/58566ee2e0604f2381ddfca4bc296dde
Autor:
Richard D Antrobus, Patrick J Lillie, Tamara K Berthoud, Alexandra J Spencer, James E McLaren, Kristin Ladell, Teresa Lambe, Anita Milicic, David A Price, Adrian V S Hill, Sarah C Gilbert
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e48322 (2012)
Current influenza vaccines have reduced immunogenicity and are of uncertain efficacy in older adults. We assessed the safety and immunogenicity of MVA-NP+M1, a viral-vectored influenza vaccine designed to boost memory T cell responses, in a group of
Externí odkaz:
https://doaj.org/article/5ae393bd353248b788b0220b71fe0d22
Publikováno v:
ImmunoTargets and Therapy
Soluble cytokine receptors can influence immune responses by modulating the biological functions of their respective ligands. These effects can be either agonistic or antagonistic and a number of soluble cytokine receptors have been shown to play cri
Autor:
Stephanie C. Burke Schinkel, Tamara K Berthoud, Sandra C. Côté, Jonathan B. Angel, Alana Stilla
Publikováno v:
AIDS. 33:985-991
Th17 cells are key regulators of functional immunity in mucosal tissues, including the gut-associated lymphoid tissue (GALT), an important site of immune impairment in HIV infection. During HIV infection, Th17 cells are lost in large numbers from the
Autor:
Sandra C, Côté, Stephanie C, Burke Schinkel, Tamara K, Berthoud, Priscila O, Barros, Maria, Sanchez-Vidales, April M, Davidson, Angela M, Crawley, Jonathan B, Angel
Publikováno v:
European Journal of Immunology
The IL‐7 receptor specific α chain, CD127, can be expressed both as a membrane‐associated (mCD127) and a soluble form (sCD127), however, the mechanisms involved in their regulation remain to be defined. We first demonstrated in primary human CD8
Publikováno v:
PLoS ONE, Vol 12, Iss 11, p e0186823 (2017)
PLoS ONE
PLoS ONE
Objectives HIV infection causes a profound depletion of gut derived Th17 cells, contributing to loss of mucosal barrier function and an increase in microbial translocation, thus driving systemic immune activation. Despite normalization of circulating