Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Tamara Jane Johnson"'
Autor:
David J. Clark, Paul Aiyetan, Naseruddin Höti, Ronald Rodriguez, Tamara Jane Johnson, Hui Zhang, Binod Kumar, Punit Shah, Shuang Yang, Wasim H. Chowdery, Arife Unal Eroglu, Yingwei Hu
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 19, Iss 10, Pp 817-829 (2017)
Although XPO5 has been characterized to have tumor-suppressor features in the miRNA biogenesis pathway, the impact of altered expression of XPO5 in cancers is unexplored. Here we report a novel "oncogenic" role of XPO5 in advanced prostate cancer. Us
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a05c3d31632df2c168423b28c14ee3a
https://doi.org/10.1016/j.neo.2017.07.008
https://doi.org/10.1016/j.neo.2017.07.008
Publikováno v:
Cancers, Vol 10, Iss 6, p 202 (2018)
Cancers
Volume 10
Issue 6
Cancers
Volume 10
Issue 6
We elucidate the role of p21/Waf-1, a cyclin-dependent kinase inhibitor, on the oncolytic infection and replication cycle of adenovirus by studying both mRNA and adenoviral proteins expression. We found that infection in the absence of p21 causes a s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::777421d54566cd5b22010f63135dc884
http://www.mdpi.com/2072-6694/10/6/202
http://www.mdpi.com/2072-6694/10/6/202
Autor:
Theodore L. DeWeese, Ronald Rodriguez, Shawn E. Lupold, Wasim H. Chowdhury, Tamara Jane Johnson, Naser Uddin Hoti, Chunyan Liu, Ying Li, Yonggang Zhang
Publikováno v:
Cancer gene therapy
Conditionally replicating adenoviruses (CRAds) utilize tissue specific promoters to control the expression of the early genes, E1A and E1B, to preferentially replicate and lyse tumor cells (oncolysis). Previous CRAds used in prostate cancer gene ther
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cc5d252e70ba9616c2f1bba5cac7da4
https://doi.org/10.1038/cgt.2013.34
https://doi.org/10.1038/cgt.2013.34
Publikováno v:
Journal of Cancer Therapy. :1012-1019
Prostate specific conditionally replicating adenoviruses (CRAd) are made by placing a tissue specific promoter upstream of one or more of the viral genes required for replication (e.g., E1A, E1B). However, one major problem associated with these vect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7081d3733036a2cf0228283654793b28
https://doi.org/10.4236/jct.2012.36131
https://doi.org/10.4236/jct.2012.36131
Autor:
Shawn E. Lupold, Tamara Jane Johnson, Wasim H. Chowdhury, Naseruddin Höti, Judit Ribas, Sadaf Mustafa, Mark Castanares, Minzhi M. Liu, Ronald Rodriguez
Publikováno v:
Cancer Gene Therapy. 17:585-597
Conditionally replicating adenoviruses (CRAds) represent a promising modality for the treatment of neoplastic diseases, including Prostate Cancer. Selectively replicating viruses can be generated by placing a tissue or cancer-specific promoter upstre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce0917602b1e1f39501e9503fb0c4569
https://doi.org/10.1038/cgt.2010.15
https://doi.org/10.1038/cgt.2010.15
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e36535 (2012)
PLoS ONE
PLoS ONE
Secreted reporter molecules offer a means to evaluate biological processes in real time without the need to sacrifice samples at pre-determined endpoints. Here we have adapted the secreted bioluminescent reporter gene, Metridia luciferase, for use in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91c05249b9486506cac47e7e24718dc8
http://europepmc.org/articles/PMC3348918?pdf=render
http://europepmc.org/articles/PMC3348918?pdf=render