Serum-Derived Extracellular Vesicles from African Swine Fever Virus-Infected Pigs Selectively Recruit Viral and Porcine Proteins

Autor: Sergio Montaner-Tarbes, Myriam Pujol, Tamara Jabbar, Philippa Hawes, Dave Chapman, Hernando del Portillo, Lorenzo Fraile, Pedro J. Sánchez-Cordón, Linda Dixon, Maria Montoya

Publikováno v: Viruses, Vol 11, Iss 10, p 882 (2019)

African swine fever is a devastating hemorrhagic infectious disease, which affects domestic and wild swines (Sus scrofa) of all breeds and ages, with a high lethality of up to 90−100% in naïve animals. The causative agent, African swine fever viru

Externí odkaz: https://doaj.org/article/57c8ed3aedf64d588225eb19e13e454f

Different routes and doses influence protection in pigs immunised with the naturally attenuated African swine fever virus isolate OURT88/3

Autor: Linda K. Dixon, Geraldine Taylor, Lynnette Goatley, Tamara Jabbar, David A. G. Chapman, Christopher L. Netherton, Maria Montoya, Ana Luisa Reis, Pedro J. Sánchez-Cordón

Publikováno v: Antiviral Research

This study compares different combinations of doses and routes of immunisation of pigs with low virulent African swine fever virus (ASFV) genotype I isolate OURT88/3, including the intramuscular and intranasal route, the latter not previously tested.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62c6bdea06fa354b0c04c92a97a1fe0e
http://europepmc.org/articles/PMC5245086

Evaluation of protection induced by immunisation of domestic pigs with deletion mutant African swine fever virus BeninΔMGF by different doses and routes

Autor: Paloma Rueda, Patricia Sastre, Tamara Jabbar, Ana Luisa Reis, Pedro J. Sánchez-Cordón, David A. G. Chapman, Linda K. Dixon, Margot Berrezaie, Lynnette C. Goatley

Publikováno v: Vaccine

Highlights • Immunised pigs with BeninΔMGF were protected against parental virulent ASFV strain. • To improve safety and efficacy new doses and routes of immunisation were tested. • Intramuscular immunisation of high doses showed the best perc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c660a69ba83246f4943e0ea49f8d49aa
https://pubmed.ncbi.nlm.nih.gov/29254837

Protection of IFNAR (-/-) mice against Bluetongue virus serotype 8, by heterologous (DNA/rMVA) and homologous (rMVA/rMVA) vaccination, expressing outer-capsid protein VP2

Autor: Tamara Jabbar, Francisco Mateos, A. Bin-Tarif, Simon Gubbins, Eva Calvo-Pinilla, Haru-Hisa Takamatsu, Oya Alpar, Javier Ortego, Katarzyna Bachanek-Bankowska, Peter P. C. Mertens, Javier Castillo-Olivares

Publikováno v: Repositorio de Resultados de Investigación del INIA
INIA: Repositorio de Resultados de Investigación del INIA
PLoS ONE
PLoS ONE, Vol 8, Iss 4, p e60574 (2013)
Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria INIA

The protective efficacy of recombinant vaccines expressing serotype 8 bluetongue virus (BTV-8) capsid proteins was tested in a mouse model. The recombinant vaccines comprised plasmid DNA or Modified Vaccinia Ankara viruses encoding BTV VP2, VP5 or VP

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a28e34f7a109c06df88e42e01e4f4e7
http://hdl.handle.net/20.500.12792/2160