Zobrazeno 1 - 10
of 232
pro vyhledávání: '"Tamara J Phillips"'
Autor:
Alexandra M Stafford, Cheryl Reed, Harue Baba, Nicole AR Walter, John RK Mootz, Robert W Williams, Kim A Neve, Lev M Fedorov, Aaron J Janowsky, Tamara J Phillips
Publikováno v:
eLife, Vol 8 (2019)
We identified a locus on mouse chromosome 10 that accounts for 60% of the genetic variance in methamphetamine intake in mice selectively bred for high versus low methamphetamine consumption. We nominated the trace amine-associated receptor 1 gene, Ta
Externí odkaz:
https://doaj.org/article/5c3d04b88cfd4fd3b5b64b83308ddda0
Autor:
Shkelzen Shabani, Sydney K Houlton, Laura Hellmuth, Erika Mojica, John R.K. Mootz, Zhen Zhu, Cheryl Reed, Tamara J Phillips
Publikováno v:
Frontiers in Neuroscience, Vol 10 (2016)
Binge/crash cycles of methamphetamine (MA) use are frequently reported by individuals suffering from MA use disorders. An MA binge is self-reported as multiple daily doses that commonly accumulate to 800 mg/day (~10 mg/kg/day for a 170 pound human).
Externí odkaz:
https://doaj.org/article/a3507f54e7754c98ae40f624c941f531
Publikováno v:
PLoS ONE, Vol 11, Iss 7, p e0158178 (2016)
Methamphetamine (MA) abuse has been linked to violence, risk-taking behaviors, decreased sexual inhibition, and criminal activity. It is important to understand mechanisms underlying these drug effects for prevention and treatment of MA-associated so
Externí odkaz:
https://doaj.org/article/6da3a5b84a2a4b81a5240f97924f25b6
Autor:
Xiao Shi, Nicole A R Walter, John H Harkness, Kim A Neve, Robert W Williams, Lu Lu, John K Belknap, Amy J Eshleman, Tamara J Phillips, Aaron Janowsky
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0152581 (2016)
Methamphetamine (MA) and neurotransmitter precursors and metabolites such as tyramine, octopamine, and β-phenethylamine stimulate the G protein-coupled trace amine-associated receptor 1 (TAAR1). TAAR1 has been implicated in human conditions includin
Externí odkaz:
https://doaj.org/article/7030c05efd874274b2cf2d34ae5accc5
Autor:
Cheryl Reed, Tamara J. Phillips
Publikováno v:
Frontiers in Psychiatry, Vol 15 (2024)
Under conditions of repeated exposure to ethanol, a sensitized locomotor stimulant response develops in some strains of mice. It has been hypothesized that the sensitized response is a consequence of tolerance development to the sedative/incoordinati
Externí odkaz:
https://doaj.org/article/b1f497f3aedf403f8f0b3ea573fd0e79
Autor:
Robert Hitzemann, Lina Gao, Suzanne S. Fei, Karina Ray, Katinka A. Vigh-Conrad, Tamara J. Phillips, Robert Searles, Rita P. Cervera-Juanes, Rupak Khadka, Timothy L. Carlson, Steven W. Gonzales, Natali Newman, Kathleen A. Grant
Publikováno v:
Advances in Drug and Alcohol Research, Vol 4 (2024)
Male rhesus monkeys (n = 24) had a biopsy of prefrontal cortical area 46 prior to chronic ethanol self-administration (n = 17) or caloric control (n = 7). Fourteen months of daily self-administration (water vs. 4% alcohol, 22 h access/day termed “o
Externí odkaz:
https://doaj.org/article/31ef99ebfcc54307aa7f7c94ae77bff8
Autor:
Justin Q. Anderson, Priscila Darakjian, Robert Hitzemann, Denesa R. Lockwood, Tamara J. Phillips, Angela R. Ozburn
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 16 (2022)
The collaborative cross (CC) founder strains include five classical inbred laboratory strains [129S1/SvlmJ (S129), A/J (AJ), C57BL/6J (B6), NOD/ShiLtJ (NOD), and NZO/HILtJ (NZO)] and three wild-derived strains [CAST/EiJ (CAST), PWK/PhJ (PWK), and WSB
Externí odkaz:
https://doaj.org/article/78e62170347c4b1fb8ce0129ee185874
Publikováno v:
Frontiers in Psychiatry, Vol 12 (2021)
We and many others have noted the advantages of using heterogeneous (HS) animals to map genes and gene networks associated with both behavioral and non-behavioral phenotypes. Importantly, genetically complex Mus musculus crosses provide substantially
Externí odkaz:
https://doaj.org/article/9fde4c9c622042a8b0eb75bfb8f7ae38
Autor:
Tamara J. Phillips, Tyler Roy, Sara J. Aldrich, Harue Baba, Jason Erk, John R. K. Mootz, Cheryl Reed, Elissa J. Chesler
Publikováno v:
Frontiers in Psychiatry, Vol 12 (2021)
Sensitivity to rewarding and reinforcing drug effects has a critical role in initial use, but the role of initial aversive drug effects has received less attention. Methamphetamine effects on dopamine re-uptake and efflux are associated with its addi
Externí odkaz:
https://doaj.org/article/26adef7841ef4a838d3af8810b6634a4
Autor:
Dayana Rodriguez-Contreras, Sheng Gong, Joseph J. Lebowitz, Lev M. Fedorov, Naeem Asad, Timothy M. Dore, Tamara J. Phillips, Christopher P. Ford, John T. Williams, Kim A. Neve
Publikováno v:
Molecular Pharmacology. 103:188-198
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::53ba8a989624b84222f557b312613ac0
https://doi.org/10.1124/molpharm.122.000606
https://doi.org/10.1124/molpharm.122.000606