Výsledky vyhledávání - "Tamara J Laskowski"

Akademický článek

Activated B cells suppress T-cell function through metabolic competition

Publikováno v: Journal for ImmunoTherapy of Cancer, Vol 10, Iss 12 (2022)

Background B cells play a pivotal role in regulating the immune response. The induction of B cell-mediated immunosuppressive function requires B cell activating signals. However, the mechanisms by which activated B cells mediate T-cell suppression ar

Externí odkaz: https://doaj.org/article/d3edf7d013de4e0baf660853daac9cb7

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Akademický článek

Gene Correction of iPSCs from a Wiskott-Aldrich Syndrome Patient Normalizes the Lymphoid Developmental and Functional Defects

Autor: Tamara J. Laskowski, Yasmine Van Caeneghem, Rasoul Pourebrahim, Chao Ma, Zhenya Ni, Zita Garate, Ana M. Crane, Xuan Shirley Li, Wei Liao, Manuel Gonzalez-Garay, Jose Carlos Segovia, David E. Paschon, Edward J. Rebar, Michael C. Holmes, Dan Kaufman, Bart Vandekerckhove, Brian R. Davis

Publikováno v: Stem Cell Reports, Vol 7, Iss 2, Pp 139-148 (2016)

Wiskott-Aldrich syndrome (WAS) is an X-linked primary immunodeficiency disease caused by mutations in the gene encoding the WAS protein (WASp). Here, induced pluripotent stem cells (iPSCs) were derived from a WAS patient (WAS-iPSC) and the endogenous

Externí odkaz: https://doaj.org/article/676abc2202b146eb97e086edfc92f229

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Activated B cells suppress T-cell function through metabolic competition

Publikováno v: Journal for immunotherapy of cancer. 10(12)

BackgroundB cells play a pivotal role in regulating the immune response. The induction of B cell-mediated immunosuppressive function requires B cell activating signals. However, the mechanisms by which activated B cells mediate T-cell suppression are

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6cc2ec49f04ccf92e072989d901cc4f
https://pubmed.ncbi.nlm.nih.gov/36543374

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Natural killer cells in antitumour adoptive cell immunotherapy

Autor: Tamara J. Laskowski, Alexander Biederstädt, Katayoun Rezvani

Publikováno v: Nature reviews. Cancer. 22(10)

Natural killer (NK) cells comprise a unique population of innate lymphoid cells endowed with intrinsic abilities to identify and eliminate virally infected cells and tumour cells. Possessing multiple cytotoxicity mechanisms and the ability to modulat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76cf6625e004fc4a5acd6ab04c87c3dd
https://pubmed.ncbi.nlm.nih.gov/35879429

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Gene Correction of iPSCs from a Wiskott-Aldrich Syndrome Patient Normalizes the Lymphoid Developmental and Functional Defects

Autor: Rasoul Pourebrahim, Bart Vandekerckhove, Xuan Shirley Li, Zhenya Ni, Zita Garate, Wei Liao, David Paschon, Manuel L. Gonzalez-Garay, Yasmine Van Caeneghem, Dan S. Kaufman, Ana M. Crane, Brian R. Davis, Chao Ma, Tamara J. Laskowski, Michael C. Holmes, José C. Segovia, Edward J. Rebar

Publikováno v: Stem Cell Reports, Vol 7, Iss 2, Pp 139-148 (2016)
STEM CELL REPORTS
Stem Cell Reports
Stem Cell Reports, vol 7, iss 2

Summary Wiskott-Aldrich syndrome (WAS) is an X-linked primary immunodeficiency disease caused by mutations in the gene encoding the WAS protein (WASp). Here, induced pluripotent stem cells (iPSCs) were derived from a WAS patient (WAS-iPSC) and the en

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97be01935ff3bef7cf877b578f5d8d73
http://www.sciencedirect.com/science/article/pii/S2213671116300959

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