Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Tamara Hernandez-Beeftink"'
Autor:
Beatriz Guillen-Guio, Megan L. Paynton, Richard J. Allen, Daniel P.W. Chin, Lauren J. Donoghue, Amy Stockwell, Olivia C. Leavy, Tamara Hernandez-Beeftink, Carl Reynolds, Paul Cullinan, Fernando Martinez, Helen L. Booth, William A. Fahy, Ian P. Hall, Simon P. Hart, Mike R. Hill, Nik Hirani, Richard B. Hubbard, Robin J. McAnulty, Ann B. Millar, Vidya Navaratnam, Eunice Oballa, Helen Parfrey, Gauri Saini, Ian Sayers, Martin D. Tobin, Moira K.B. Whyte, Ayodeji Adegunsoye, Naftali Kaminski, Shwu-Fan Ma, Mary E. Strek, Yingze Zhang, Tasha E. Fingerlin, Maria Molina-Molina, Margaret Neighbors, X. Rebecca Sheng, Justin M. Oldham, Toby M. Maher, Philip L. Molyneaux, Carlos Flores, Imre Noth, David A. Schwartz, Brian L. Yaspan, R. Gisli Jenkins, Louise V. Wain, Edward J. Hollox
Publikováno v:
ERJ Open Research, Vol 10, Iss 1 (2024)
Introduction Idiopathic pulmonary fibrosis (IPF) is a chronic interstitial pneumonia marked by progressive lung fibrosis and a poor prognosis. Recent studies have highlighted the potential role of infection in the pathogenesis of IPF, and a prior ass
Externí odkaz:
https://doaj.org/article/473a7531d84a4f018fe7880dc13a5162
Xanthine oxidoreductase gene polymorphisms are associated with high risk of sepsis and organ failure
Autor:
Li Gao, Nicholas Rafaels, Tanda M. Dudenkov, Mahendra Damarla, Rachel Damico, James P. Maloney, Marc Moss, Greg S. Martin, Jonathan Sevransky, Carl Shanholtz, Dan L. Herr, Joe G.N. Garcia, Tamara Hernandez-Beeftink, Jesús Villar, Carlos Flores, Terri H. Beaty, Roy Brower, Paul M. Hassoun, Kathleen C. Barnes
Publikováno v:
Respiratory Research, Vol 24, Iss 1, Pp 1-12 (2023)
Abstract Background Sepsis and associated organ failures confer substantial morbidity and mortality. Xanthine oxidoreductase (XOR) is implicated in the development of tissue oxidative damage in a wide variety of respiratory and cardiovascular disorde
Externí odkaz:
https://doaj.org/article/03c6fd5c4e4d4efd835394c679a13f8b
Autor:
Patrick R. Lawler, MD, MPH, Garen Manvelian, PhD, Alida Coppi, PhD, Amy Damask, PhD, Michael N. Cantor, MD, Manuel A. R. Ferreira, PhD, Charles Paulding, PhD, Nilanjana Banerjee, PhD, Dadong Li, PhD, Susan Jorgensen, MS, Richa Attre, PhD, David J. Carey, PhD, Kristi Krebs, PhD, Lili Milani, PhD, Kristian Hveem, MD, Jan K. Damås, PhD, Erik Solligård, PhD, Stefan Stender, MD, Anne Tybjærg-Hansen, MD, Børge G. Nordestgaard, MD, Tamara Hernandez-Beeftink, PhD, Tormod Rogne, MD, Carlos Flores, PhD, Jesús Villar, MD, Keith R. Walley, MD, Vincent X. Liu, MD, Alison E. Fohner, PhD, Luca A. Lotta, MD, Christos A. Kyratsous, PhD, Mark W. Sleeman, PhD, Michel Scemama, MD, Richard DelGizzi, MS, Robert Pordy, MD, Julie E. Horowitz, PhD, Aris Baras, MD, Greg S. Martin, MD, Philippe Gabriel Steg, MD, Gregory G. Schwartz, MD, Michael Szarek, PhD, Shaun G. Goodman, MD
Publikováno v:
Critical Care Explorations, Vol 5, Iss 11, p e0997 (2023)
OBJECTIVES:. Treatments that prevent sepsis complications are needed. Circulating lipid and protein assemblies—lipoproteins play critical roles in clearing pathogens from the bloodstream. We investigated whether early inhibition of proprotein conve
Externí odkaz:
https://doaj.org/article/9668af2bf04b4033991c97345adef80d
Autor:
Tamara Hernandez-Beeftink, Beatriz Guillen-Guio, Jose M. Lorenzo-Salazar, Almudena Corrales, Eva Suarez-Pajes, Rui Feng, Luis A. Rubio-Rodríguez, Megan L. Paynton, Raquel Cruz, M. Isabel García-Laorden, Miryam Prieto-González, Aurelio Rodríguez-Pérez, Demetrio Carriedo, Jesús Blanco, Alfonso Ambrós, Elena González-Higueras, Elena Espinosa, Arturo Muriel, Eduardo Tamayo, María M. Martin, Leonardo Lorente, David Domínguez, Abelardo García de Lorenzo, Heather M. Giannini, John P. Reilly, Tiffanie K. Jones, José M. Añón, Marina Soro, Ángel Carracedo, Louise V. Wain, Nuala J. Meyer, Jesús Villar, Carlos Flores, the Genetics of Sepsis (GEN-SEP) Network
Publikováno v:
Critical Care, Vol 26, Iss 1, Pp 1-10 (2022)
Abstract Background Sepsis is a severe systemic inflammatory response to infections that is accompanied by organ dysfunction and has a high mortality rate in adult intensive care units. Most genetic studies have identified gene variants associated wi
Externí odkaz:
https://doaj.org/article/6a41f741af084c4dab8e4ca22baabbb6
Autor:
Eva Suarez-Pajes, Eva Tosco-Herrera, Melody Ramirez-Falcon, Silvia Gonzalez-Barbuzano, Tamara Hernandez-Beeftink, Beatriz Guillen-Guio, Jesús Villar, Carlos Flores
Publikováno v:
Journal of Clinical Medicine, Vol 12, Iss 11, p 3713 (2023)
Acute respiratory distress syndrome (ARDS) is a life-threatening lung condition that arises from multiple causes, including sepsis, pneumonia, trauma, and severe coronavirus disease 2019 (COVID-19). Given the heterogeneity of causes and the lack of s
Externí odkaz:
https://doaj.org/article/47ce61252f2c46da84801a26cdc56721
Autor:
Tamara Hernandez-Beeftink, Itahisa Marcelino-Rodríguez, Beatriz Guillen-Guio, Héctor Rodríguez-Pérez, Jose M. Lorenzo-Salazar, Almudena Corrales, Ana Díaz-de Usera, Rafaela González-Montelongo, David Domínguez, Elena Espinosa, Jesús Villar, Carlos Flores
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
Sepsis is a severe systemic inflammatory response to infections that is accompanied by organ dysfunction. Although the ancestral genetic background is a relevant factor for sepsis susceptibility, there is a lack of studies using the genetic singulari
Externí odkaz:
https://doaj.org/article/8e4f6199576d406eb66d888735ce9e30
Autor:
Tamara Hernandez-Beeftink, Itahisa Marcelino-Rodríguez, Beatriz Guillen-Guio, Héctor Rodríguez-Pérez, Jose M. Lorenzo-Salazar, Almudena Corrales, Ana Díaz-de Usera, Rafaela González-Montelongo, David Domínguez, Elena Espinosa, Jesús Villar, Carlos Flores
Publikováno v:
Frontiers in medicine. 9
Sepsis is a severe systemic inflammatory response to infections that is accompanied by organ dysfunction. Although the ancestral genetic background is a relevant factor for sepsis susceptibility, there is a lack of studies using the genetic singulari
Autor:
Tamara Hernández-Beeftink, Beatriz Guillen-Guio, Héctor Rodríguez-Pérez, Itahisa Marcelino-Rodríguez, Jose M. Lorenzo-Salazar, Almudena Corrales, Miryam Prieto-González, Aurelio Rodríguez-Pérez, Demetrio Carriedo, Jesús Blanco, Alfonso Ambrós, Elena González-Higueras, Nancy G. Casanova, Manuel González-Garay, Elena Espinosa, Arturo Muriel, David Domínguez, Abelardo García de Lorenzo, José M. Añón, Marina Soro, Javier Belda, Joe G. N. Garcia, Jesús Villar, Carlos Flores
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Acute respiratory distress syndrome (ARDS) is an inflammatory process of the lungs that develops primarily in response to pulmonary or systemic sepsis, resulting in a disproportionate death toll in intensive care units (ICUs). Given its role as a cri
Externí odkaz:
https://doaj.org/article/a86e6e599596488c9563a8636f416698
Autor:
Héctor Rodríguez-Pérez, Tamara Hernández-Beeftink, José M. Lorenzo-Salazar, José L. Roda-García, Carlos J. Pérez-González, Marcos Colebrook, Carlos Flores
Publikováno v:
BMC Bioinformatics, Vol 20, Iss 1, Pp 1-4 (2019)
Abstract Background The Oxford Nanopore Technologies (ONT) MinION portable sequencer makes it possible to use cutting-edge genomic technologies in the field and the academic classroom. Results We present NanoDJ, a Jupyter notebook integration of tool
Externí odkaz:
https://doaj.org/article/c8565ec9aa9c479891ddbf4359f4f849
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 16, p 4004 (2019)
The excessive hospital mortality associated with acute respiratory distress syndrome (ARDS) in adults mandates an urgent need for developing new therapies and tools for the early risk assessment of these patients. ARDS is a heterogeneous syndrome wit
Externí odkaz:
https://doaj.org/article/d5cc8a4166c24943b431cf6d1c1e2c17