Zobrazeno 1 - 10
of 73
pro vyhledávání: '"Tamara Hermida-Gómez"'
Autor:
Andrea Dalmao-Fernández, Tamara Hermida-Gómez, Uxia Nogueira-Recalde, Ignacio Rego-Pérez, Francisco J. Blanco-Garcia, Mercedes Fernández-Moreno
Publikováno v:
Cells, Vol 13, Iss 11, p 976 (2024)
Authors have demonstrated that apoptosis activation is a pathway related to cartilage degradation characteristics of the OA process. Autophagy is an adaptive response to protect cells from various environmental changes, and defects in autophagy are l
Externí odkaz:
https://doaj.org/article/2e366a3d4f1a4af881a11ff6f50791b6
Autor:
María Piñeiro-Ramil, Clara Sanjurjo-Rodríguez, Silvia Rodríguez-Fernández, Tamara Hermida-Gómez, Francisco J. Blanco-García, Isaac Fuentes-Boquete, Carlos Vaamonde-García, Silvia Díaz-Prado
Publikováno v:
Bone & Joint Research, Vol 12, Iss 1, Pp 46-57 (2023)
AimsAfter a few passages of in vitro culture, primary human articular chondrocytes undergo senescence and loss of their phenotype. Most of the available chondrocyte cell lines have been obtained from cartilage tissues different from diarthrodial join
Externí odkaz:
https://doaj.org/article/312a3eaeac5d45eb917aa2300523847e
Autor:
Mercedes Fernández-Moreno, Tamara Hermida-Gómez, Nicholas Larkins, Alan Reynolds, Francisco J. Blanco
Publikováno v:
Pharmaceuticals, Vol 17, Iss 1, p 118 (2024)
Osteoarthritis (OA) is a chronic joint disease leading to cartilage loss and reduction in the joint space which results in pain. The current pharmacological treatment of OA is inadequate and pharmacological interventions focus on symptom management.
Externí odkaz:
https://doaj.org/article/1f485ed2c55f42f699c660d689025137
Autor:
María Piñeiro-Ramil, Elena F. Burguera, Tamara Hermida-Gómez, Beatriz Caramés, Natividad Oreiro-Villar, Rosa Meijide-Faílde, Francisco J. Blanco, Carlos Vaamonde-García
Publikováno v:
Antioxidants, Vol 11, Iss 4, p 628 (2022)
Different findings indicate that type 2 diabetes is an independent risk factor for osteoarthritis (OA). However, the mechanisms underlying the connection between both diseases remain unclear. Changes in the balance of hydrogen sulphide (H2S) are thou
Externí odkaz:
https://doaj.org/article/c5cde8e0800647279a17a78394efeef8
Autor:
María Piñeiro-Ramil, Rocío Castro-Viñuelas, Clara Sanjurjo-Rodríguez, Silvia Rodríguez-Fernández, Tamara Hermida-Gómez, Francisco J. Blanco-García, Isaac Fuentes-Boquete, Silvia Díaz-Prado
Publikováno v:
Stem Cells International, Vol 2020 (2020)
Human bone marrow-derived mesenchymal stromal cells (MSCs) obtained from aged patients are prone to senesce and diminish their differentiation potential, therefore limiting their usefulness for osteochondral regenerative medicine approaches or to stu
Externí odkaz:
https://doaj.org/article/4f30757a854546e78f28450e4affd361
Autor:
Andrea Dalmao-Fernández, Jenny Lund, Tamara Hermida-Gómez, María E Vazquez-Mosquera, Ignacio Rego-Pérez, Francisco J. Blanco, Mercedes Fernández-Moreno
Publikováno v:
Cells, Vol 9, Iss 4, p 809 (2020)
Osteoarthritis (OA) is the most frequent joint disease; however, the etiopathogenesis is still unclear. Chondrocytes rely primarily on glycolysis to meet cellular energy demand, but studies implicate impaired mitochondrial function in OA pathogenesis
Externí odkaz:
https://doaj.org/article/d63ba2c33b1247a6be032af0fc640c78
Autor:
Clara Sanjurjo-Rodríguez, Rocío Castro-Viñuelas, Tamara Hermida-Gómez, Tania Fernández-Vázquez, Isaac Manuel Fuentes-Boquete, Francisco Javier de Toro-Santos, Silvia María Díaz-Prado, Francisco Javier Blanco-García
Publikováno v:
PLoS ONE, Vol 12, Iss 1, p e0171231 (2017)
INTRODUCTION:Knowledge of ovine mesenchymal stromal cells (oMSCs) is currently expanding. Tissue engineering combining scaffolding with oMSCs provides promising therapies for the treatment of osteochondral diseases. PURPOSE:The aim was to isolate and
Externí odkaz:
https://doaj.org/article/1f35ed05d03c4208a67df103982fa6fa
Autor:
Mercedes Fernández-Moreno, Tamara Hermida-Gómez, M Esther Gallardo, Andrea Dalmao-Fernández, Ignacio Rego-Pérez, Rafael Garesse, Francisco J Blanco
Publikováno v:
PLoS ONE, Vol 11, Iss 10, p e0164199 (2016)
The generation of Rho-0 cells requires the use of an immortalization process, or tumor cell selection, followed by culture in the presence of ethidium bromide (EtBr), incurring the drawbacks its use entails. The purpose of this work was to generate R
Externí odkaz:
https://doaj.org/article/f5c616e2bc224f4cbab2f7dd8f4e4db4
Autor:
Claudia Cicione, Emma Muiños-López, Tamara Hermida-Gómez, Isaac Fuentes-Boquete, Silvia Díaz-Prado, Francisco J. Blanco
Publikováno v:
Stem Cells International, Vol 2013 (2013)
Background. The interests in mesenchymal stem cells (MSCs) and their application in cell therapy have resulted in a better understanding of the basic biology of these cells. Recently hypoxia has been indicated as crucial for complete chondrogenesis.
Externí odkaz:
https://doaj.org/article/d4afcb388cc245988dd3f0483c31cb75
Autor:
Alejandro Durán-Sotuela, Mercedes Fernandez-Moreno, Victoria Suárez-Ulloa, Jorge Vázquez-García, Sara Relaño, Tamara Hermida-Gómez, Vanesa Balboa-Barreiro, Lucia Lourido-Salas, Valentina Calamia, Patricia Fernandez-Puente, Cristina Ruiz-Romero, Juan Fernández-Tajes, Carlos Vaamonde-García, María C de Andrés, Natividad Oreiro, Francisco J Blanco, Ignacio Rego-Perez
Publikováno v:
Annals of the Rheumatic Diseases. :ard-2022
ObjectivesTo identify mitochondrial DNA (mtDNA) genetic variants associated with the risk of rapid progression of knee osteoarthritis (OA) and to characterise their functional significance using a cellular model of transmitochondrial cybrids.MethodsT
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7175400eb0cad8a595b9c3c8657b178d
https://doi.org/10.1136/ard-2022-223570
https://doi.org/10.1136/ard-2022-223570