Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Tamara Heermann"'
Autor:
Beatrice Ramm, Dominik Schumacher, Andrea Harms, Tamara Heermann, Philipp Klos, Franziska Müller, Petra Schwille, Lotte Søgaard-Andersen
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-24 (2023)
Abstract Cell division is spatiotemporally precisely regulated, but the underlying mechanisms are incompletely understood. In the social bacterium Myxococcus xanthus, the PomX/PomY/PomZ proteins form a single megadalton-sized complex that directly po
Externí odkaz:
https://doaj.org/article/ab4adfac3a5f4b9abad4a25d7d3e4627
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
The ability to dynamically control protein-protein interactions and localization of proteins is critical in synthetic biological systems. Here the authors develop a peptide-based molecular switch that regulates dimer formation and lipid membrane targ
Externí odkaz:
https://doaj.org/article/4376b19d20ae4edab075ab555f27de80
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-9 (2020)
Abstract As one of the key elements in bacterial cell division, the cytoskeletal protein FtsZ appears to be highly involved in circumferential treadmilling along the inner membrane, yielding circular vortices when transferred to flat membranes. Howev
Externí odkaz:
https://doaj.org/article/8abeee3857ef495c848283c51c99a60d
Publikováno v:
ACS Synthetic Biology. 12:108-119
Reversible membrane targeting of proteins is one of the key regulators of cellular interaction networks, for example, for signaling and polarization. So-called "membrane switches" are thus highly attractive targets for the design of minimal cells but
Publikováno v:
Nature Methods
In spite of their great importance in biology, methods providing access to spontaneous molecular interactions with and on biological membranes have been sparse. The recent advent of mass photometry to quantify mass distributions of unlabeled biomolec
Autor:
Beatrice Ramm, Dominik Schumacher, Andrea Harms, Tamara Heermann, Philipp Klos, Franziska Müller, Petra Schwille, Lotte Søgaard-Andersen
Publikováno v:
bioRxiv
SummaryCell division is spatiotemporally precisely regulated, but the underlying mechanisms are incompletely understood. In the social, predatory bacterium Myxococcus xanthus, the PomX/PomY/PomZ proteins form a single large megadalton-sized complex t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88c576232ced2cbd35afb83997e55948
https://doi.org/10.1101/2022.09.12.507586
https://doi.org/10.1101/2022.09.12.507586
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Fletcher, J M, Woolfson, D N & Schwille, P 2021, ' De novo design of a reversible phosphorylation-dependent switch for membrane targeting ', Nature Communications, vol. 12, no. 1, 1472 . https://doi.org/10.1038/s41467-021-21622-5
Nature Communications
Fletcher, J M, Woolfson, D N & Schwille, P 2021, ' De novo design of a reversible phosphorylation-dependent switch for membrane targeting ', Nature Communications, vol. 12, no. 1, 1472 . https://doi.org/10.1038/s41467-021-21622-5
Nature Communications
Modules that switch protein-protein interactions on and off are essential to develop synthetic biology; for example, to construct orthogonal signaling pathways, to control artificial protein structures dynamically, and for protein localization in cel
Publikováno v:
Bioconjugate Chemistry
As a key mechanism underpinning many biological processes, protein self-organization has been extensively studied. However, the potential to apply the distinctive, nonlinear biochemical properties of such self-organizing systems to biotechnological p
Bottom-up synthetic biology is a powerful tool for uncovering the mechanisms underlying vital biological processes, such as signaling and cell polarization. The core principle of reconstituting cellular functions in their minimal forms can be achieve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3776b1259e43b05e50548f1d61396553
https://doi.org/10.1101/2022.03.03.482798
https://doi.org/10.1101/2022.03.03.482798
Publikováno v:
Journal of Visualized Experiments.
Short-lived or transient interactions of macromolecules at and with lipid membranes, an interface where a multitude of essential biological reactions take place, are inherently difficult to assess with standard biophysical methods. The introduction o