Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Tamara Hüsser"'
Autor:
Reinhard Dummer, Marina Bacac, Pablo Umana, Mitchell P Levesque, Christine Trumpfheller, Mi He, Bhavesh Soni, Petra C Schwalie, Tamara Hüsser, Caroline Waltzinger, Duvini De Silva, Ylva Prinz, Laura Krümpelmann, Samuele Calabro, Ines Matos, Maries van den Broek, Stephan Gasser
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 6 (2022)
Externí odkaz:
https://doaj.org/article/86af3a62742e4d618016ad79388f8eb6
Autor:
Pablo Umaña, Christian Klein, Christiane Neumann, Laurent Lariviere, Anne Freimoser-Grundschober, Anna Maria Giusti, Heather Hinton, Katharine Bray-French, Wolfgang Richter, Tamara Hüsser, Ramona Schlenker, Florian Limani, Sarah Diggelmann, Valeria Nicolini, Anne Schoenle, Marine Richard, Roberta Bianchi, Stanford Chen, Mario Perro, Johannes Sam, Sylvia Herter, Sara Colombetti, Marina Bacac
Supplemental Video 3. In vitro visualization of the dynamics of CD20-TCB (white) during interaction between CD8+ T-cells (green) and tumor cells (blue). The video focuses on an example of CD20-TCB-mediated CD8+ T-cell cytotoxicity of tumor cells. T-c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2c34bb5766e137770cfc15b52be8812
https://doi.org/10.1158/1078-0432.22470684.v1
https://doi.org/10.1158/1078-0432.22470684.v1
Autor:
Pablo Umaña, Christian Klein, Christiane Neumann, Laurent Lariviere, Anne Freimoser-Grundschober, Anna Maria Giusti, Heather Hinton, Katharine Bray-French, Wolfgang Richter, Tamara Hüsser, Ramona Schlenker, Florian Limani, Sarah Diggelmann, Valeria Nicolini, Anne Schoenle, Marine Richard, Roberta Bianchi, Stanford Chen, Mario Perro, Johannes Sam, Sylvia Herter, Sara Colombetti, Marina Bacac
Supplemental Figure 1. Assessment of the binding characteristics and cynomolgus monkey cross-reactivity of CD20-TCB. Supplemental Figure 2. Tumor cell lysis mediated by different CD20-targeting TCB antibodies. Supplemental Figure 3. T-cell and B-cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6f83b355ee080929db2938b3999bdc6
https://doi.org/10.1158/1078-0432.22470699.v1
https://doi.org/10.1158/1078-0432.22470699.v1
Autor:
Pablo Umaña, Christian Klein, Christiane Neumann, Laurent Lariviere, Anne Freimoser-Grundschober, Anna Maria Giusti, Heather Hinton, Katharine Bray-French, Wolfgang Richter, Tamara Hüsser, Ramona Schlenker, Florian Limani, Sarah Diggelmann, Valeria Nicolini, Anne Schoenle, Marine Richard, Roberta Bianchi, Stanford Chen, Mario Perro, Johannes Sam, Sylvia Herter, Sara Colombetti, Marina Bacac
Supplemental Video 1. In vitro visualization of the dynamics of untargeted TCB (white) during the interaction between CD8+ T-cells (green) and tumor cells (blue).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5528bbaeae8c4578de2abac8ea8e47c1
https://doi.org/10.1158/1078-0432.22470693.v1
https://doi.org/10.1158/1078-0432.22470693.v1
Autor:
Pablo Umaña, Christian Klein, Christiane Neumann, Laurent Lariviere, Anne Freimoser-Grundschober, Anna Maria Giusti, Heather Hinton, Katharine Bray-French, Wolfgang Richter, Tamara Hüsser, Ramona Schlenker, Florian Limani, Sarah Diggelmann, Valeria Nicolini, Anne Schoenle, Marine Richard, Roberta Bianchi, Stanford Chen, Mario Perro, Johannes Sam, Sylvia Herter, Sara Colombetti, Marina Bacac
Purpose: Despite promising clinical activity, T-cell–engaging therapies including T-cell bispecific antibodies (TCB) are associated with severe side effects requiring the use of step-up-dosing (SUD) regimens to mitigate safety. Here, we present a n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::421e81a5be4c9af62b584bb4bcc20383
https://doi.org/10.1158/1078-0432.c.6527658
https://doi.org/10.1158/1078-0432.c.6527658
Autor:
Pablo Umaña, Christian Klein, Christiane Neumann, Laurent Lariviere, Anne Freimoser-Grundschober, Anna Maria Giusti, Heather Hinton, Katharine Bray-French, Wolfgang Richter, Tamara Hüsser, Ramona Schlenker, Florian Limani, Sarah Diggelmann, Valeria Nicolini, Anne Schoenle, Marine Richard, Roberta Bianchi, Stanford Chen, Mario Perro, Johannes Sam, Sylvia Herter, Sara Colombetti, Marina Bacac
Supplemental Video 2. In vitro visualization of the dynamics of CD20-TCB (white) during the interaction between CD8+ T-cells (green) and tumor cells (blue).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74444c2ec5be11dba70eb0e8147dca27
https://doi.org/10.1158/1078-0432.22470690.v1
https://doi.org/10.1158/1078-0432.22470690.v1
Autor:
Pablo Umaña, Christian Klein, Christiane Neumann, Laurent Lariviere, Anne Freimoser-Grundschober, Anna Maria Giusti, Heather Hinton, Katharine Bray-French, Wolfgang Richter, Tamara Hüsser, Ramona Schlenker, Florian Limani, Sarah Diggelmann, Valeria Nicolini, Anne Schoenle, Marine Richard, Roberta Bianchi, Stanford Chen, Mario Perro, Johannes Sam, Sylvia Herter, Sara Colombetti, Marina Bacac
Supplemental materials and methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5594f5b3911dca8d52fd682a0acecc3f
https://doi.org/10.1158/1078-0432.22470696.v1
https://doi.org/10.1158/1078-0432.22470696.v1
Autor:
Pablo Umaña, Christian Klein, Christiane Neumann, Laurent Lariviere, Anne Freimoser-Grundschober, Anna Maria Giusti, Heather Hinton, Katharine Bray-French, Wolfgang Richter, Tamara Hüsser, Ramona Schlenker, Florian Limani, Sarah Diggelmann, Valeria Nicolini, Anne Schoenle, Marine Richard, Roberta Bianchi, Stanford Chen, Mario Perro, Johannes Sam, Sylvia Herter, Sara Colombetti, Marina Bacac
Supplemental Table 1. Overview of CD20-targeting T-cell bispecific molecules evaluated in the current study. Supplemental Table 2. Tumor cell lines and EC50 values of tumor cell lysis. Supplemental Table 3. Assessment of the activity in ex vivo prima
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f563536186d4caa72a439f6e060c463
https://doi.org/10.1158/1078-0432.22470708.v1
https://doi.org/10.1158/1078-0432.22470708.v1
Autor:
Johannes Sam, Llucia Alberti Servera, Sina Nassiri, Atul Sethi, Alison Ribeiro, Gabrielle Leclercq-Cohen, Petra Schwalie, Tamara Hüsser, Emilio Yangueez, Sylvia Herter, Christian Klein, Pablo Umana, Marina Bacac
Publikováno v:
Cancer Research. 83:4117-4117
T Cell Bispecific Antibodies (TCBs) are potent molecules that induce durable complete remissions with a favorable safety profile in Relapsed Refractory Non Hodgkin Lymphoma patients. Despite the promising clinical efficacy, a proportion of patients e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::876206b3712a8e67596e50722171f5b5
https://doi.org/10.1158/1538-7445.am2023-4117
https://doi.org/10.1158/1538-7445.am2023-4117
Abstract LB558: Single cell profiling of PBMCs reveals correlates of clinical response to glofitamab
Autor:
Sina Nassiri, Lucas Habegger, Petra Gerber, Vinko Tosevski, Tamara Hüsser, Emilio Yanguez, Sylvia Herter, Martin Weisser, Koorosh Korfi, Pablo Umana, Emily Piccione, Ann-Marie Bröske, Marina Bacac
Publikováno v:
Cancer Research. 82:LB558-LB558
Glofitamab is a novel CD20-targeted bispecific T cell-engaging antibody that has demonstrated significant clinical efficacy in aggressive forms of Non-Hodgkin Lymphoma (aNHL). Despite significant clinical efficacy in aNHL (Hutchings et al. JCO 2021),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::946d39998be00bd419f07b53d9c7c234
https://doi.org/10.1158/1538-7445.am2022-lb558
https://doi.org/10.1158/1538-7445.am2022-lb558