Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Tamara G.M. Treptow"'
Autor:
Marcelo Gonçalves Montes D'Oca, Caroline Da Ros Montes D’Oca, Mariana Appel Hort, Rui Carlos Medeiros Alves Sobrinho, Patrick M. de Oliveira, Luana Machado Farias, Marcelo Augusto Germani Marinho, Tamara G.M. Treptow, Dennis Russowsky, Franciele Saes de Oliveira, Ana Paula Horn, Rafael C. Brinkerhoff
Publikováno v:
MedChemComm. 9:1282-1288
Monastrol is a small cell-permeable heterocyclic molecule that is recognized as an inhibitor of mitotic kinesin Eg5. Heterocyclic–fatty acid derivatives are a new class of compounds with a broad range of biological activities. This work describes a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::016a54bc163e596be144decea0d25b47
https://doi.org/10.1039/c8md00169c
https://doi.org/10.1039/c8md00169c
Autor:
Thaís C. Batista, Bruno Igure Gonçalves, Andressa C. H. Weber, Dennis Russowsky, Carolina R. L. Hack, Caroline Da Ros Montes D’Oca, Tamara G.M. Treptow, Marcelo Gonçalves Montes D'Oca, Larissa M. Porciuncula
Publikováno v:
Journal of the American Oil Chemists' Society. 93:1399-1406
The 1,3-dicarbonyl compounds are important building blocks to obtain products with various biological activities and technological applications. In this work, we used a simple transesterification method to develop fatty acetoacetates in a solvent-fre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d104622f852216b0de3d920517e36064
https://doi.org/10.1007/s11746-016-2879-5
https://doi.org/10.1007/s11746-016-2879-5
Autor:
Milene Medeiros de Moraes, Marcelo Gonçalves Montes D'Oca, Ana Paula de Souza Votto, Luciana A. Piovesan, Tamara G.M. Treptow, Wystan K.O. Teixeira
Publikováno v:
Bioorganic chemistry. 72
Melanoma is the most dangerous type of skin cancer due to the occurrence of metastases. This work is aimed at studying the effects of the insertion of palmitic and oleic acid chain into monastrol in the melanoma cell line, B16F10. Cells were treated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13cf8c85d64f37bd8926d24f571912b8
https://pubmed.ncbi.nlm.nih.gov/28460356
https://pubmed.ncbi.nlm.nih.gov/28460356
Autor:
Christianne Gazzana Salbego, Caroline Da Ros Montes D’Oca, Juliana Bender Hoppe, Marcelo Gonçalves Montes D'Oca, Tamara G.M. Treptow, Ana Maria Oliveira Battastini, Dennis Russowsky, Elisa Helena Farias Jandrey, Luciana A. Piovesan, Fabrício Figueiró, Sabrina B. Rosa, Priscila S. Taborda
Publikováno v:
European journal of medicinal chemistry. 95
We described the first synthesis of fatty acid 3,4-dihydropyrimidinones (DHPM-fatty acids) using the Biginelli multicomponent reaction. Antiproliferative activity on two glioma cell lines (C6 rat and U-138-MG human) was also reported. The novel DHPM-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ee5f39cc5b6e2e78091b22243a5b0d0
https://pubmed.ncbi.nlm.nih.gov/25863023
https://pubmed.ncbi.nlm.nih.gov/25863023
Autor:
Tamara G.M. Treptow, João Carvalho, Marieli Oliveira Rodrigues, Daiane S. dos Santos, Luciana A. Piovesan, Carolina R. L. Hack, Ana Lúcia Tasca Gois Ruiz, Marcelo Gonçalves Montes D'Oca, Débora Barbosa Vendramini-Costa, Caroline Da Ros Montes D’Oca
Publikováno v:
Bioorganic & Medicinal Chemistry. (2):340-347
In the work, the in vitro antiproliferative activity of a series of synthetic fatty acid amides were investigated in seven cancer cell lines. The study revealed that most of the compounds showed antiproliferative activity against tested tumor cell li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e23919d3ea5ec4cf57cca455c4d8b95