Výsledky vyhledávání - "Tamara Eisele"

The overnight reduction of amyloid β 1-42 plasma levels is diminished by the extent of sleep fragmentation, sAPP-β, and APOE ε4 in psychiatrists on call

Autor: Timo Grimmer, Bastian Fatke, Marion Ortner, Alexander Kurz, Sandra Lüscher, Alexander Hapfelmeier, Hans Förstl, Anna-Mareike Parchmann, Dirk Schwerthöffer, Michael Rentrop, Felix Müller-Sarnowski, Oliver Goldhardt, Theresa Laub, Patricia Hölzle, Panagiotis Alexopoulos, Tamara Eisele

Publikováno v: Alzheimer'sdementia : the journal of the Alzheimer's AssociationREFERENCES. 16(5)

Introduction In mice there might be an association between sleep deprivation and amyloid β plasma levels. Hence, we examined whether amyloid plasma levels are associated with sleep duration or fragmentation in 17 psychiatrists on-call. Methods Amylo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06d792da723ae761c20f6d87204a19b1
https://pubmed.ncbi.nlm.nih.gov/32270596

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The National Institute on Aging-Alzheimer’s Association research criteria for mild cognitive impairment due to Alzheimer’s disease: predicting the outcome

Autor: Panagiotis Alexopoulos, Stefan Wagenpfeil, Robert Perneczky, Alexander Kurz, Liang-Hao Guo, Tamara Eisele

Publikováno v: European Archives of Psychiatry and Clinical Neuroscience. 263:325-333

The National Institute on Aging-Alzheimer's Association (NIA-AA) clinical research criteria for mild cognitive impairment (MCI) due to Alzheimer's disease (AD) incorporate the use of biomarkers to classify patients according to the likelihood of the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7240bd305fe1d3257443e29261983481
https://doi.org/10.1007/s00406-012-0349-0

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Association of the Tau Haplotype H2 With Age at Onset and Functional Alterations of Glucose Utilization in Frontotemporal Dementia

Autor: Tamara Eisele, Alexander Drzezga, Simon M. Laws, Bernd Ibach, Alexander Kurz, Robert Perneczky, Janine Diehl-Schmid, Josef Bäuml, Hans Förstl, Matthias Riemenschneider

Publikováno v: American Journal of Psychiatry. 164:1577-1584

The microtubule-associated protein tau gene (MAPT) contains two extended haplotypes, H1 and H2, which have been linked with sporadic tauopathies. However, there is little evidence as to how these haplotypes may influence the clinical features of the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9ed8073168b7c84066838b000a68ae1
https://doi.org/10.1176/appi.ajp.2007.06091456

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Lack of association between a single nucleotide polymorphism within the choline acetyltransferase gene and patients with Alzheimer's disease

Autor: Alexander Kurz, S Schwarz, J. Diehl, Matthias Riemenschneider, Hans Förstl, Ulrich Müller, Tamara Eisele

Publikováno v: Neuroscience Letters. 343:167-170

Alterations of the cholinergic system may account for typical clinical and pathophysiological disturbances of Alzheimer's disease (AD). In particular, a marked decline of choline acetyltransferase activity (CHAT) and as a consequence of acetylcholine

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f9fd46bcecf1779cc7326fdbce14d1f
https://doi.org/10.1016/s0304-3940(03)00380-x

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P4‐045: EFFICIENCY OF THE RATIO OF CEREBROSPINAL FLUID Aβ42/Aβ40 CONCENTRATIONS IN DETECTING ALZHEIMER'S DISEASE: A STEP FORWARDS

Autor: Tamara Eisele, Panagiotis Alexopoulos

Publikováno v: Alzheimer's & Dementia. 10

classify patients with only one biomarker value beyond the cut-off. Alternative classification strategies must be developed. The aim of the current study was to apply a classification and decision tree model for better classification of AD patients f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d7dea6180ade544d6b1d6ffe002d80b6
https://doi.org/10.1016/j.jalz.2014.05.1559

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No association of lipase C polymorphisms with Alzheimer's disease

Autor: Patricia Friedrich, Simon M. Laws, Tamara Eisele, Klaus Eckart, Hans Förstl, Alexander Kurz, Matthias Riemenschneider

Publikováno v: Neurobiology of aging. 31(12)

Hepatic lipase, also known as hepatic triglyceride lipase (LIPC), much like the major genetic risk factor for Alzheimer's disease (AD), apolipoprotein E (APOE), is associated with altered lipid metabolism. As such this link makes LIPC a potential fun

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59dade83c725478042ee0cac61e87b3a
https://pubmed.ncbi.nlm.nih.gov/19155102

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No association of TDP-43 with sporadic frontotemporal dementia

Autor: Tamara Eisele, Hans Foerstl, Robert Perneczky, Ruth Vukovich, Janine Diehl-Schmid, Patricia Friedrich, Bernd Ibach, Matthias Riemenschneider, Axel Schumacher

Publikováno v: Neurobiology of aging. 30(1)

A hyperphosphorylated, ubiquitinated form of TDP-43, known as pathologic TDP-43, was shown to be a central component of ubiquitin-positive, tau-negative and alpha-synuclein-negative inclusions in frontotemporal lobar degeneration (FTLD-U) and amytrop

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acb0d8a4342cbdcc08379aa7e19225cb
https://pubmed.ncbi.nlm.nih.gov/17614162

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Fine mapping of the MAPT locus using quantitative trait analysis identifies possible causal variants in Alzheimer's disease

Autor: Janine Diehl-Schmid, Alexander Kurz, Simon M. Laws, Matthias Riemenschneider, Patricia Friedrich, Tamara Eisele, Jakob Müller, Josef Bäuml, Hans Förstl

Publikováno v: Molecular psychiatry. 12(5)

In addition to senile plaques, neurofibrillary tangles are characteristic of Alzheimer's disease (AD) pathology, suggesting a clear involvement of the microtubule-associated protein tau (MAPT) in AD. Recent findings, suggesting that the H1c haplotype

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a23cca404f588428ca1748d8c61df899
https://pubmed.ncbi.nlm.nih.gov/17179995

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Genetic analysis of MAPT haplotype diversity in frontotemporal dementia

Autor: Bernd Ibach, Alexander Kurz, Matthias Riemenschneider, Simon M. Laws, Tamara Eisele, Patricia Friedrich, Jakob Müller, Josef Bäuml, Janine Diehl-Schmid, Hans Förstl

Publikováno v: Neurobiology of aging. 29(8)

The H1 haplotype of the tau gene, MAPT, has been linked to the sporadic tauopathies corticobasal degeneration and progressive supranuclear palsy; however, there have been inconsistent findings regarding association with frontotemporal dementia (FTD).

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4530502407c5f3a12be98ae8ad3db066
https://pubmed.ncbi.nlm.nih.gov/17386961

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