New characterization and safety evaluation of human limbal stem cells used in clinical application: fidelity of mitotic process and mitotic spindle morphologies

Autor: Marija Zekušić, Marina Bujić Mihica, Marija Skoko, Kruno Vukušić, Patrik Risteski, Jelena Martinčić, Iva M. Tolić, Krešo Bendelja, Snježana Ramić, Tamara Dolenec, Ivana Vrgoč Zimić, Dominik Puljić, Ivanka Petric Vicković, Renata Iveković, Ivanka Batarilo, Uršula Prosenc Zmrzljak, Alan Hoffmeister, Tiha Vučemilo

Publikováno v: Stem Cell Research & Therapy, Vol 14, Iss 1, Pp 1-26 (2023)

Abstract Background Limbal stem cells (LSCs) are crucial for the regeneration of the corneal epithelium in patients with limbal stem cell deficiency (LSCD). Thus, LSCs during cultivation in vitro should be in highly homogeneous amounts, while potency

Externí odkaz: https://doaj.org/article/1ea97ef887f741b2bd77b5d00bf8449d

Detection of Limbal Stem Cells Adhered to Melt Electrospun Silk Fibroin and Gelatin-Modified Polylactic Acid Scaffolds

Autor: Emilija Zdraveva, Krešo Bendelja, Luka Bočkor, Tamara Dolenec, Budimir Mijović

Publikováno v: Polymers, Vol 15, Iss 3, p 777 (2023)

Limbal stem cells (LSCs) are of paramount importance in corneal epithelial tissue repair. The cornea becomes opaque in case of limbal stem cell deficiency (LSCD), which may cause serious damage to the ocular visual function. There are many techniques

Externí odkaz: https://doaj.org/article/dc2cfeb1334c446d904d605f73581fc2

Bioactivity Comparison of Electrospun PCL Mats and Liver Extracellular Matrix as Scaffolds for HepG2 Cells

Autor: Igor Slivac, Emilija Zdraveva, Fran Ivančić, Bojan Žunar, Tamara Holjevac Grgurić, Višnja Gaurina Srček, Ivan-Krešimir Svetec, Tamara Dolenec, Emi Govorčin Bajsić, Mirna Tominac Trcin, Budimir Mijović

Publikováno v: Polymers, Vol 13, Iss 2, p 279 (2021)

Cells grown on bioactive matrices have immensely advanced many aspects of biomedical research related to drug delivery and tissue engineering. Our main objective was to perform simple evaluation of the structural and biotic qualities of cell scaffold

Externí odkaz: https://doaj.org/article/33d389cbe4b4402bb60f0439ae535261

Poly(ε-caprolactone) Titanium Dioxide and Cefuroxime Antimicrobial Scaffolds for Cultivation of Human Limbal Stem Cells

Autor: Mirna Tominac Trcin, Emilija Zdraveva, Tamara Dolenec, Ivana Vrgoč Zimić, Marina Bujić Mihica, Ivanka Batarilo, Iva Dekaris, Valentina Blažević, Igor Slivac, Tamara Holjevac Grgurić, Emi Govorčin Bajsić, Ksenija Markov, Iva Čanak, Sunčica Kuzmić, Anita Tarbuk, Antoneta Tomljenović, Nikolina Mrkonjić, Budimir Mijović

Publikováno v: Polymers, Vol 12, Iss 8, p 1758 (2020)

Limbal Stem Cell Deficiency (LSCD) is a very serious and painful disease that often results in impaired vision. Cultivation of limbal stem cells for clinical application is usually performed on carriers such as amniotic membrane or surgical fibrin ge

Externí odkaz: https://doaj.org/article/b4cab73997164bfaac1fd26bf5d0236e

Preparation and characterization of electrospun PCL/Silk fibroin scaffolds

Autor: Mirna Tominac Trcin, Tamara Holjevac Grgurić, Budimir Mijović, Emi Govorčin Bajsić, Nikolina Mrkonjić, Sunčica Kuzmić, Igor Slivac, Emilija Zdraveva, Tamara Dolenec, Ivana Vrgoč Zimić

Publikováno v: Chemical and Biochemical Engineering Quarterly, Vol 35, Iss 1, Pp 31-42 (2021)
Chemical and Biochemical Engineering Quarterly
Volume 35
Issue 1

Natural polymer-based scaffolds are generally considered as favourable matrices for the adhesion and growth of cells in tissue repair. One of the most popular materials in this respect is silk fibroin, known for its wide usage in biomedical applicati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7a32eb3372094f999db8a7794e2ffeb
https://www.bib.irb.hr/1123979