Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Tamara Diehl"'
Autor:
Daniela Hanisch, Andrea Krumm, Tamara Diehl, Carla M. Stork, Mario Dejung, Falk Butter, Ella Kim, Walburgis Brenner, Gerhard Fritz, Thomas G. Hofmann, Wynand P. Roos
Publikováno v:
Cell Death and Disease, Vol 13, Iss 4, Pp 1-12 (2022)
Abstract Overexpression of histone deacetylases (HDACs) in cancer commonly causes resistance to genotoxic-based therapies. Here, we report on the novel mechanism whereby overexpressed class I HDACs increase the resistance of glioblastoma cells to the
Externí odkaz:
https://doaj.org/article/2cfac13acf6e4a9caee84f906260180f
Autor:
Holger H H Erb, Julia Bodenbender, Florian Handle, Tamara Diehl, Lukas Donix, Igor Tsaur, Martin Gleave, Axel Haferkamp, Johannes Huber, Susanne Fuessel, Eva Juengel, Zoran Culig, Christian Thomas
Publikováno v:
PLoS ONE, Vol 15, Iss 8, p e0237248 (2020)
Despite enzalutamide's efficacy in delaying the progression of metastatic castration-resistant prostate cancer (CRPC), resistance to this anti-androgen inevitably occurs. Several studies have revealed that the signal transducer and activator of trans
Externí odkaz:
https://doaj.org/article/4e67266c59d74563ae1dc628b1acd121
Publikováno v:
Methods in Molecular Biology ISBN: 9781071627877
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::133e63c623863f35ba99152395146753
https://doi.org/10.1007/978-1-0716-2788-4_19
https://doi.org/10.1007/978-1-0716-2788-4_19
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2589
This book chapter describes a plasmid-based reporter method, first described by Bennardo et al. (2008) that we use in our laboratory for determining the activity of the repair of DNA double-strand breaks by nonhomologous end joining. This method can
Autor:
Holger H.H. Erb, Tamara Diehl, Gustavo B. Baretton, Eva Jüngel, Manuela Hemmerlein-Thomas, Peter Sparwasser, Igor Tsaur, Andreas Neisius, Christian Thomas, Ulrich Sommer, Axel Haferkamp
Publikováno v:
Urologia Internationalis. 104:253-262
Introduction: Androgen receptor variant 7 (AR-V7) plays an important role in the progression of castration-resistant prostate cancer (CRPC) and has shown potential as a predictive biomarker in circulating tumour cells (CTCs) isolated from the bloodst
Autor:
Franziska R. Traube, Natércia F. Brás, Wynand P. Roos, Corinna C. Sommermann, Tamara Diehl, Robert J. Mayer, Armin R. Ofial, Markus Müller, Hendrik Zipse, Thomas Carell
5-Aza-2’-deoxycytidine (Decitabine, AzadC) is a nucleoside analogue, which is in clinical use to treat patients with myelodysplastic syndrome or acute myeloid leukemia. Its mode of action is unusual because the compound is one of the few drugs that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::69bbded6190d1634f1034c188b1174f2
https://doi.org/10.1101/2022.01.19.476908
https://doi.org/10.1101/2022.01.19.476908
Autor:
Daniela Hanisch, Andrea Krumm, Tamara Diehl, Carla M. Stork, Mario Dejung, Falk Butter, Ella Kim, Walburgis Brenner, Gerhard Fritz, Thomas G. Hofmann, Wynand P. Roos
Publikováno v:
Cell deathdisease. 13(4)
Overexpression of histone deacetylases (HDACs) in cancer commonly causes resistance to genotoxic-based therapies. Here, we report on the novel mechanism whereby overexpressed class I HDACs increase the resistance of glioblastoma cells to the SN1 meth