Výsledky vyhledávání - "Tamara D. Payero"

Akademický článek

Modulation of Multiple Gene Clusters’ Expression by the PAS-LuxR Transcriptional Regulator PteF

Autor: Cláudia M. Vicente, Tamara D. Payero, Antonio Rodríguez-García, Eva G. Barreales, Antonio de Pedro, Fernando Santos-Beneit, Jesús F. Aparicio

Publikováno v: Antibiotics, Vol 11, Iss 8, p 994 (2022)

PAS-LuxR transcriptional regulators are conserved proteins governing polyene antifungal biosynthesis. PteF is the regulator of filipin biosynthesis from Streptomyces avermitilis. Its mutation drastically abates filipin, but also oligomycin production

Externí odkaz: https://doaj.org/article/573086844cdd4df2bcd46469bf478950

Zobrazit plný text záznamu

Akademický článek

Structural and Bioactivity Characterization of Filipin Derivatives from Engineered Streptomyces filipinensis Strains Reveals Clues for Reduced Haemolytic Action

Autor: Eva G. Barreales, Ángel Rumbero, Tamara D. Payero, Antonio de Pedro, Ester Jambrina, Jesús F. Aparicio

Publikováno v: Antibiotics, Vol 9, Iss 7, p 413 (2020)

The rise in the number of immunocompromised patients has led to an increased incidence of fungal infections, with high rates of morbidity and mortality. Furthermore, misuse of antifungals has boosted the number of resistant strains to these agents; t

Externí odkaz: https://doaj.org/article/e38ccab5e36940499a947c50e0d393fb

Zobrazit plný text záznamu

Akademický článek

Phosphate effect on filipin production and morphological differentiation in Streptomyces filipinensis and the role of the PhoP transcription factor.

Autor: Eva G Barreales, Tamara D Payero, Antonio de Pedro, Jesús F Aparicio

Publikováno v: PLoS ONE, Vol 13, Iss 12, p e0208278 (2018)

The biosynthesis of the antifungal filipin in Streptomyces filipinensis is very sensitive to phosphate regulation. Concentrations as low as 2.5 mM block filipin production. This effect is, at least in part, produced by repression of the transcription

Externí odkaz: https://doaj.org/article/28ce09b2c16040bc9c183f5ee2ece1ae

Zobrazit plný text záznamu

Plný text ve formátu HTML

Modulation of multiple gene clusters expression by a single PAS-LuxR transcriptional regulator

Autor: Cláudia M. Vicente, Tamara D. Payero, Antonio Rodríguez-García, Eva G. Barreales, Antonio de Pedro, Fernando Santos-Beneit, Jesús F. Aparicio

PAS-LuxR transcriptional regulators are highly conserved enzymes governing polyene macrolide antifungal biosynthesis. PteF is one of such regulators, situated in the polyene macrolide filipin gene cluster from Streptomyces avermitilis. Its mutation l

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d8e7238d261c07869ddad835f8ba068c
https://doi.org/10.1101/2022.06.10.495441

Zobrazit plný text záznamu

The Streptomyces filipinensis Gamma-Butyrolactone System Reveals Novel Clues for Understanding the Control of Secondary Metabolism

Autor: Ester Jambrina, Eva G. Barreales, Jesús F. Aparicio, Tamara D. Payero

Publikováno v: Applied and Environmental Microbiology

Streptomyces GBLs are important signaling molecules that trigger antibiotic production in a quorum sensing-dependent manner. We have characterized the GBL system from S. filipinensis, finding that two key players of this system, the GBL receptor and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::454c3de2909aadf8070666ab6d622057
https://doi.org/10.1128/aem.00443-20

Zobrazit plný text záznamu

Structural and Bioactivity Characterization of Filipin Derivatives from Engineered Streptomyces filipinensis Strains Reveals Clues for Reduced Haemolytic Action

Autor: Ester Jambrina, Angel Rumbero, Antonio de Pedro, Eva G. Barreales, Jesús F. Aparicio, Tamara D. Payero

Publikováno v: Antibiotics, Vol 9, Iss 413, p 413 (2020)
Antibiotics
Volume 9
Issue 7
Biblos-e Archivo. Repositorio Institucional de la UAM
instname

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d05b4b5ed44442226e05e0000675289c
https://www.mdpi.com/2079-6382/9/7/413

Zobrazit plný text záznamu

Akademický článek

Hierarchical control on polyene macrolide biosynthesis: PimR modulates pimaricin production via the PAS-LuxR transcriptional activator PimM.

Autor: Javier Santos-Aberturas, Cláudia M Vicente, Tamara D Payero, Lara Martín-Sánchez, Carmen Cañibano, Juan F Martín, Jesús F Aparicio

Publikováno v: PLoS ONE, Vol 7, Iss 6, p e38536 (2012)

Control of polyene macrolide production in Streptomyces natalensis is mediated by the transcriptional activator PimR. This regulator combines an N-terminal domain corresponding to the Streptomyces antibiotic regulatory protein (SARP) family of transc

Externí odkaz: https://doaj.org/article/d6846085a137452284e13b06761630f0

Zobrazit plný text záznamu

Phosphate effect on filipin production and morphological differentiation in Streptomyces filipinensis and the role of the PhoP transcription factor

Autor: Jesús F. Aparicio, Tamara D. Payero, Eva G. Barreales, Antonio de Pedro

Publikováno v: PLoS ONE, Vol 13, Iss 12, p e0208278 (2018)
PLoS ONE

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4de2c914f4de561103f6b104cac23d66
https://doi.org/10.1371/journal.pone.0208278

Zobrazit plný text záznamu

Molecular Control of Polyene Macrolide Biosynthesis

Autor: Cláudia M. Vicente, Jesús F. Aparicio, Tamara D. Payero, Juan F. Martín, Susana M. Guerra, Javier Santos-Aberturas

Publikováno v: Journal of Biological Chemistry
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2011, 286 (11), pp.9150-9161. ⟨10.1074/jbc.M110.182428⟩

International audience; Control of polyene macrolide production in Streptomyces natalensis is mediated by the transcriptional activator PimM. This regulator, which combines an N-terminal PAS domain with a C-terminal helix-turn-helix motif, is highly

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0252f1b6d1a60f3c53aea71a7efbb642
https://doi.org/10.1074/jbc.m110.182428

Zobrazit plný text záznamu

Pathway-specific regulation revisited: cross-regulation of multiple disparate gene clusters by PAS-LuxR transcriptional regulators

Autor: Cláudia M. Vicente, Javier Santos-Aberturas, Eva G. Barreales, Antonio de Pedro, Jesús F. Aparicio, Tamara D. Payero

Publikováno v: Applied Microbiology and Biotechnology
Applied Microbiology and Biotechnology, Springer Verlag, 2015, 99 (12), pp.5123-5135. ⟨10.1007/s00253-015-6472-x⟩

International audience; PAS-LuxR regulators are highly conserved proteins devoted to the control of antifungal production by binding to operators located in given promoters of polyene biosynthetic genes. The canonical operator of PimM, archetype of t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c7258b27340f6df4680031b8ee2bc15
https://hal.insa-toulouse.fr/hal-02559683

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání