Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Tamara Borgonovo"'
Autor:
Isadora May Vaz, Tamara Borgonovo, Tais Hanae Kasai-Brunswick, Danúbia Silva dos Santos, Fernanda Cristina Paccola Mesquita, Juliana Ferreira Vasques, Fernanda Gubert, Carmen Lúcia Kuniyoshi Rebelatto, Alexandra Cristina Senegaglia, Paulo Roberto Slud Brofman
Publikováno v:
Genetics and Molecular Biology, Vol 44, Iss 3 (2021)
Abstract Induced pluripotent stem cells (iPSCs) are generated from adult cells that have been reprogrammed to pluripotency. However, in vitro cultivation and genetic reprogramming increase genetic instability, which could result in chromosomal abnorm
Externí odkaz:
https://doaj.org/article/dc0555a2caa245d7849122084b2fdd43
Autor:
Fernanda Gubert, Juliana F. Vasques, Tatiane D. Cozendey, Pablo Domizi, María Fernanda Toledo, Tais H. Kasai-Brunswick, Camila Hochman-Mendez, Mário Campos Junior, Verônica Marques Zembrzuski, Marli P.S. Loureiro, José M.B. Lima, Claudio H. Gress, Giselda M.K. Cabello, Pedro H. Cabello, Tamara Borgonovo, Isadora M. Vaz, Rosane Silva, Rosalia Mendez-Otero
Publikováno v:
Stem Cell Research, Vol 39, Iss , Pp - (2019)
Induced pluripotent stem cell (iPSC) line were generated from erythroblasts of a Brazilian patient with familiar form of amyotrophic lateral sclerosis (ALS). NGS analysis demonstrated that patient carried a mutation in SOD1 gene, as well as a deletio
Externí odkaz:
https://doaj.org/article/10afc6d7f50e40469bca00049c6738f4
Autor:
Fernanda Gubert, Juliana F. Vasques, Tatiane D. Cozendey, Pablo Domizi, María Fernanda Toledo, Tais H. Kasai-Brunswick, Marli P.S. Loureiro, José M.B. Lima, Claudio H. Gress, Giselda M.K. Cabello, Pedro H. Cabello, Tamara Borgonovo, Isadora M. Vaz, Rosane Silva, Rosalia Mendez-Otero
Publikováno v:
Stem Cell Research, Vol 37, Iss , Pp - (2019)
Induced pluripotent stem cell (iPSC) lines were generated from erythroblasts of two patients with amyotrophic lateral sclerosis (ALS) and two healthy individuals. One familial and one sporadic ALS patients were used, both with genetic alterations in
Externí odkaz:
https://doaj.org/article/f097656aa55746a99fd0a9b218d040ff
Autor:
Fernanda Cristina Paccola Mesquita, Tais Hanae Kasai-Brunswick, Fernanda de Mello e Souza Valente Gubert, Tamara Borgonovo, Danúbia Silva-dos-Santos, Dayanada Silva de Araújo, Antonio Carlos Campos-de-Carvalho, Adriana Bastos Carvalho
Publikováno v:
Stem Cell Research, Vol 15, Iss 3, Pp 445-448 (2015)
The human ihFib3.2 iPS cell line was generated from dermal fibroblasts obtained from a healthy donor. Lentiviral particles were produced with the polycistronic hSTEMCCA vector with Oct4, Sox2, cMyc and Klf4 as reprogramming factors.
Externí odkaz:
https://doaj.org/article/91be49ad00ed43eeb8d7819ceb36e0bf
Autor:
Tamara Borgonovo, Isadora May Vaz, Alexandra Cristina Senegaglia, Carmen Lucia Kuniyoshi Rebelatto, Paulo Roberto Slud Brofman
Publikováno v:
Revista Brasileira de Hematologia e Hemoterapia, Vol 36, Iss 3, Pp 202-207 (2014)
OBJECTIVE: To present the initial results of first three years of implementation of a genetic evaluation test for bone marrow-derived mesenchymal stem cells in a Cell Technology Center.METHODS: A retrospective study was carried out of 21 candidates f
Externí odkaz:
https://doaj.org/article/634e96cec90841949086ab83345ddbb6
Autor:
Aline Rangel-Pozzo, Daiane Corrêa de Souza, Ana Teresa Schmid-Braz, Ana Paula de Azambuja, Thais Ferraz-Aguiar, Tamara Borgonovo, Sabine Mai
Publikováno v:
Cells, Vol 8, Iss 4, p 304 (2019)
The disease course of myelodysplastic syndromes (MDS) features chromosome instability and clonal evolution, leading to the sequential acquisition of novel cytogenetic aberrations and the accumulation of these abnormalities in the bone marrow. Althoug
Externí odkaz:
https://doaj.org/article/d59b3dba8155477da93b727530dd2177
Autor:
Tamara Borgonovo, Enilze M.S.F. Ribeiro, Déborah Afonso Cornélio, Ana Teresa Schmid-Braz, Valderez Ravaglio Jamur, Lismeri Wuicik, Loraine Beatriz Acosta Veiga, Néria A. Maia Ehmke, Ricardo Pasquini, Iglenir João Cavalli
Publikováno v:
Genetics and Molecular Biology, Vol 28, Iss 4, Pp 654-660 (2005)
Bone marrow cytogenetic studies were performed on 93 patients with primary myelodysplastic syndrome (MDS) diagnosed at the Clinical Hospital of the Federal University of Paraná, Brazil. Chromosomal alterations were observed in 69% of the patients. M
Externí odkaz:
https://doaj.org/article/8a2368b4fd204974986c06b7020ca537
Autor:
Camila Oliveira Pereira, Daniela Vandresen Pillonetto, Tamara Borgonovo, Carmen Lúcia Kuniyoshi Rebelatto, Miriam Lacerda Barbosa, Maria Cristina Finger, Samantha Nichele, Joanna Trennepohl, Gisele Loth, Carmem Bonfim
Publikováno v:
International Journal of Laboratory Hematology. 44:900-906
Fanconi anaemia (FA) is a rare genetic disorder marked by progressive bone marrow failure, chromosomal fragility, and increased cancer susceptibility. Laboratory diagnosis includes chromosomal instability test and mutation investigation. A total of 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6df8659692700c8824035cb7f8295da0
https://doi.org/10.1111/ijlh.13874
https://doi.org/10.1111/ijlh.13874
Autor:
Gabriel Neiman, Fernanda Mesquita, Marcus N. dos Santos, Emiliano Medei, Gustavo Monnerat, Antonio Carlos Carvalho, Fernanda Gubert, Raiana A. Q. Barbosa, Isadora M. Vaz, Jorge L. Coutinho, Danúbia Silva dos Santos, Paulo C. Arantes, Adriana Bastos Carvalho, Tamara Borgonovo, Santiago Gabriel Miriuka, Dayana S. Araujo, Isabela de Carvalho Leitão, Fernando Cruz, Tais Hanae Kasai-Brunswick
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-9 (2019)
Scientific Reports
Scientific Reports
Patient-specific cardiomyocytes obtained from induced pluripotent stem cells (CM-iPSC) offer unprecedented mechanistic insights in the study of inherited cardiac diseases. The objective of this work was to study a type 2 long QT syndrome (LQTS2)-asso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3eea2c59eccc22c54a03ef45570fe890
http://link.springer.com/article/10.1038/s41598-019-55837-w
http://link.springer.com/article/10.1038/s41598-019-55837-w
Autor:
Fernanda Gubert, Isadora M. Vaz, Fernanda Mesquita, Tais Hanae Kasai-Brunswick, Tamara Borgonovo, Paulo Roberto Slud Brofman, Juliana Ferreira Vasques, Alexandra Cristina Senegaglia, Danúbia Silva dos Santos, Carmen Lúcia Kuniyoshi Rebelatto
Publikováno v:
Genetics and Molecular Biology, Volume: 44, Issue: 3, Article number: e20200147, Published: 03 SEP 2021
Genetics and Molecular Biology
Genetics and Molecular Biology, Vol 44, Iss 3 (2021)
Genetics and Molecular Biology v.44 n.3 2021
Sociedade Brasileira de Genética (SBG)
instacron:SBG
Genetics and Molecular Biology
Genetics and Molecular Biology, Vol 44, Iss 3 (2021)
Genetics and Molecular Biology v.44 n.3 2021
Sociedade Brasileira de Genética (SBG)
instacron:SBG
Induced pluripotent stem cells (iPSCs) are generated from adult cells that have been reprogrammed to pluripotency. However, in vitro cultivation and genetic reprogramming increase genetic instability, which could result in chromosomal abnormalities.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0480472a92ad69bbc9602a22dd07158d
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572021000400103&lng=en&tlng=en
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572021000400103&lng=en&tlng=en
