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pro vyhledávání: '"Tamara B. Franklin"'
Publikováno v:
Neurobiology of Stress, Vol 17, Iss , Pp 100434- (2022)
Exposures to stress at all stages of development can lead to long-term behavioural effects, in part through changes in the epigenome. This review describes rodent research suggesting that stress in prenatal, postnatal, adolescent and adult stages lea
Externí odkaz:
https://doaj.org/article/ad93c2cc4598484b9b60c6ccd00bf174
Autor:
Tamara B. Franklin
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 13 (2019)
Recent advances in neural circuitry techniques, like optogenetics and chemogenetics, have allowed for a greater understanding of the periaqueductal gray (PAG) and its importance in predator and prey behaviors. These studies in rodents have highlighte
Externí odkaz:
https://doaj.org/article/07cda8364a164b9da5d7ce386b18af0d
Autor:
Tamara B. Franklin, Isabelle M. Mansuy
Publikováno v:
Neurobiology of Disease, Vol 39, Iss 1, Pp 61-65 (2010)
The epigenome is the overall epigenetic state of a cell and represents the ensemble of chromatin modifications. It is an essential mechanism for the regulation of the genome that depends on modifications of DNA and histones but does not involve any c
Externí odkaz:
https://doaj.org/article/54aa6b7fe4bc4d808a5d7d825a99139e
Publikováno v:
Neuroscience & Biobehavioral Reviews. 112:634-647
Transgenic mouse models have been used extensively to model the cognitive impairments arising from Alzheimer’s disease (AD)-related pathology. However, less is known about the relationship between AD-related pathology and the behavioural and psycho
Autor:
Tamara B. Franklin, Ryan V. Wheeler
Publikováno v:
Epigenomics. 11:1557-1560
Publikováno v:
Neurobiology of Stress, Vol 17, Iss, Pp 100434-(2022)
Exposures to stress at all stages of development can lead to long-term behavioural effects, in part through changes in the epigenome. This review describes rodent research suggesting that stress in prenatal, postnatal, adolescent and adult stages lea
Autor:
Katharina Gapp, Tamara B. Franklin
Although controversial, there is increasing evidence from a variety of disciplines suggesting that transgenerational epigenetic inheritance is a mechanism that can act as an environmentally driven rapid form of adaptation in mammals. It has been sugg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5810315741c0e8a91f976e3d29823ab7
https://doi.org/10.1016/b978-0-12-823577-5.00026-x
https://doi.org/10.1016/b978-0-12-823577-5.00026-x
Publikováno v:
Journal of neuroscience researchREFERENCES. 99(1)
Social withdrawal and agitation/aggression are common behavioral and psychological symptoms of dementia presented by Alzheimer's disease (AD) patients, with males exhibiting more aggressive behaviors than females. Some transgenic mouse models of AD a
In addition to memory impairments, patients with Alzheimer’s disease (AD) exhibit a number of behavioural and psychological symptoms that can affect social interactions over the course of the disease. While altered social interactions have been dem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be670be44f90bdc7e4da7ff693079560
https://doi.org/10.1101/471714
https://doi.org/10.1101/471714
Autor:
Tamara B. Franklin, Isabelle M. Mansuy, Martin Roszkowski, Gretchen van Steenwyk, Francesca Manuella
Publikováno v:
Environmental Epigenetics, 4 (2)
Environmental Epigenetics
Environmental Epigenetics
In the past decades, evidence supporting the transmission of acquired traits across generations has reshaped the field of genetics and the understanding of disease susceptibility. In humans, pioneer studies showed that exposure to famine, endocrine d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12d33bbef8484ee8d3f6e95cb6103129
https://hdl.handle.net/20.500.11850/312580
https://hdl.handle.net/20.500.11850/312580