Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Tamara A Potapova"'
Autor:
Tamara A Potapova, Jay R Unruh, Juliana Conkright-Fincham, Charles AS Banks, Laurence Florens, David Alan Schneider, Jennifer L Gerton
Publikováno v:
eLife, Vol 12 (2023)
Ribosome biogenesis is a vital and highly energy-consuming cellular function occurring primarily in the nucleolus. Cancer cells have an elevated demand for ribosomes to sustain continuous proliferation. This study evaluated the impact of existing ant
Externí odkaz:
https://doaj.org/article/fc3278bdd9414a3bbee3d9190e4221a8
Autor:
Tamara A. Potapova, Jay R. Unruh, Andrew C. Box, William D. Bradford, Christopher W. Seidel, Brian D. Slaughter, Shamilene Sivagnanam, Yuping Wu, Rong Li
Publikováno v:
BioTechniques, Vol 59, Iss 6, Pp 335-346 (2015)
Multispectral karyotyping analyzes all chromosomes in a single cell by labeling them with chromosome-specific probes conjugated to unique combinations of fluorophores. Currently available multispectral karyotyping systems require the purchase of spec
Externí odkaz:
https://doaj.org/article/6bd7744e3dca485397903d3766213412
Autor:
Tamara A. Potapova, Jay R. Unruh, Juliana Conkright-Fincham, Charles A. S. Banks, Laurence Florens, David A. Schneider, Jennifer L. Gerton
Ribosome biogenesis is one of the most essential and energy-consuming cellular functions. It takes place mainly in the nucleolus. For cancer cells, the nucleolar function is especially important due to the high demand for ribosomes to support continu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b94477b8de1b94cedc502e45f8536ce3
https://doi.org/10.1101/2022.11.18.517150
https://doi.org/10.1101/2022.11.18.517150
Autor:
Zulin, Yu, Tamara A, Potapova
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2458
This protocol describes the fluorescence in situ hybridization (FISH) of DNA probes on mitotic chromosome spreads optimized for two super-resolution microscopy approaches-structured illumination microscopy (SIM) and stimulated emission depletion (STE
Autor:
Zulin Yu, Tamara A. Potapova
Publikováno v:
Methods in Molecular Biology ISBN: 9781071621394
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c671e27295af45cb65a62461451ce859
https://doi.org/10.1007/978-1-0716-2140-0_20
https://doi.org/10.1007/978-1-0716-2140-0_20
Autor:
Jennifer L. Gerton, Jay R. Unruh, Zulin Yu, Giulia Rancati, Hua Li, Tamara A. Potapova, Martha R. Stampfer
Publikováno v:
The Journal of Cell Biology
Potapova et al. use superresolution microscopy to describe linkages between ribosomal DNA on heterologous human chromosomes whose formation depends on the transcription factor UBF and topoisomerase II. Linkages persist in the absence of cohesion but
Autor:
Tamara A. Potapova, Jennifer L. Gerton
Publikováno v:
Chromosome Research. 27:109-127
The nucleolus constitutes a prominent nuclear compartment, a membraneless organelle that was first documented in the 1830s. The fact that specific chromosomal regions were present in the nucleolus was recognized by Barbara McClintock in the 1930s, an
Autor:
David Porubsky, Gulhan Kaya, Ruta Sahasrabudhe, James C. Mullikin, Joel Armstrong, Amy B. Wilfert, Jonathan Wood, Edmund Howe, Ariel Gershman, Amalia Dutra, Jon Matthew Belton, Alexander M. Chang, Karen H. Miga, Valerie A. Schneider, Adam M. Phillippy, Alice Young, Andrey Bzikadze, Tamara A. Potapova, Rosa Ana Risques, Anthony D. Schmitt, Tina A. Graves Lindsay, Gerard G. Bouffard, Nancy F. Hansen, Benedict Paten, Josh Quick, Ira M. Hall, Glennis A. Logsdon, Sergey Koren, Kristof Tigyi, Nadine Holmes, Daniela C. Soto, Beth A. Sullivan, Jeanne Fredrickson, Robert S. Fulton, Siddarth Selvaraj, Milinn Kremitzki, Winston Timp, Nicholas J. Loman, Arang Rhie, Evan E. Eichler, Megan Y. Dennis, Kerstin Howe, Jennifer L. Gerton, Urvashi Surti, Valerie Maduro, Christopher Markovic, Pavel A. Pevzner, Françoise Thibaud-Nissen, William Chow, Shelise Brooks, Evgenia Pak, Matthew Loose, Mitchell R. Vollger
Publikováno v:
Nature, vol 585, iss 7823
Nature
Nature
After two decades of improvements, the current human reference genome (GRCh38) is the most accurate and complete vertebrate genome ever produced. However, no single chromosome has been finished end to end, and hundreds of unresolved gaps persist1,2.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b763e6dc69f68a2c414f6d2d8a9e4a86
https://escholarship.org/uc/item/88w7j3n7
https://escholarship.org/uc/item/88w7j3n7
Autor:
Shamilene Sivagnanam, William D. Bradford, Tamara A. Potapova, Rong Li, Yuping Wu, Christopher Seidel, Brian D. Slaughter, Jay R. Unruh, Andrew C. Box
Publikováno v:
BioTechniques. 59:335-346
Multispectral karyotyping analyzes all chromosomes in a single cell by labeling them with chromosome-specific probes conjugated to unique combinations of fluorophores. Currently available multispectral karyotyping systems require the purchase of spec
Autor:
Tamara A. Potapova, Gary J. Gorbsky
Publikováno v:
Biology, Vol 6, Iss 1, p 12 (2017)
Biology
Biology
Mistakes during cell division frequently generate changes in chromosome content, producing aneuploid or polyploid progeny cells. Polyploid cells may then undergo abnormal division to generate aneuploid cells. Chromosome segregation errors may also in