Výsledky vyhledávání - "Tamara, Mucenic"

Akademický článek

O papel das proteínas reguladoras do complemento CD55/CD59 em células de sangue periférico de pacientes com lúpus eritematoso sistêmico The role of CD55/CD59 complement regulatory proteins on peripheral blood cells of systemic lupus erythematosus patients

Autor: Ana Paula Alegretti, Tamara Mucenic, João Carlos Tavares Brenol, Ricardo Machado Xavier

Publikováno v: Revista Brasileira de Reumatologia, Vol 49, Iss 3, Pp 276-287 (2009)

CD55 e CD59 são proteínas de membrana ancoradas por glicosilfosfatidilinositol que apresentam propriedades reguladoras da ativação da cascata do complemento. Essa regulação ocorre através da inibição da C3 convertase pelo CD55 e prevenção

Externí odkaz: https://doaj.org/article/af50bdf5e53b4a51a4dcded54c54edf5

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AB0288 SAFETY OF BELIMUMAB IN PATIENTS WITH ACTIVE SYSTEMIC LUPUS ERYTHEMATOSUS: YEAR 2 FOLLOW-UP OF A LARGE PHASE 4, RANDOMISED, DOUBLE-BLIND, PLACEBO-CONTROLLED STUDY

Autor: A. Liu, S. Muzaffar, Regina Kurrasch, James Cheng-Chung Wei, Tamara Mucenic, Morton Scheinberg, Saira Z Sheikh, S. Fernandes, Rajesh Punwaney, N.L. Fox, H. Quasny, William Stohl, Julia Harris, D. Tegzova, David M. Roth

Publikováno v: Annals of the Rheumatic Diseases. 80:1170-1171

Background:Belimumab (BEL), a recombinant human monoclonal antibody that inhibits B-lymphocyte stimulator (BLyS), is approved for the treatment of systemic lupus erythematosus (SLE). Clinical studies have yielded varying incidence rates of mortality

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::81f13a36d431be455bf7755e36e44cd8
https://doi.org/10.1136/annrheumdis-2021-eular.2552

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LB0012 HEADLINE RESULTS FOR A PHASE 4, 52-WEEK, RANDOMISED, DOUBLE-BLIND, PLACEBO-CONTROLLED STUDY TO ASSESS ADVERSE EVENTS OF SPECIAL INTEREST (AESI) IN ADULTS WITH ACTIVE, AUTOANTIBODY-POSITIVE SYSTEMIC LUPUS ERYTHEMATOSUS (SLE) RECEIVING BELIMUMAB

Autor: David M. Roth, Damon Bass, Saira Z Sheikh, James Cheng-Chung Wei, Morton Scheinberg, William Stohl, Kevin S. Thorneloe, D. Tegzova, Rajesh Punwaney, Julia Harris, Roger A. Levy, Jorge Alfonso Ross Terres, Beulah Ji, Tamara Mucenic

Publikováno v: Oral Presentations.

Background Belimumab (BEL) is approved in adults with active, autoantibody-positive SLE. Phase 2, 3 and long-term extension studies showed a favourable benefit-risk profile. However, numerical differences in the incidence of mortality, infections, hy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::42c27b1e8abb7fb3065777238e4f3bfe
https://doi.org/10.1136/annrheumdis-2019-eular.8720

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Association of the HLA-G gene +3142C>G polymorphism with systemic lupus erythematosus

Autor: Tamara Mucenic, Ricardo Machado Xavier, Odirlei André Monticielo, José Artur Bogo Chies, Camila Rosat Consiglio, João Carlos Tavares Brenol, Tiago Degani Veit

Publikováno v: Tissue Antigens. 77:540-545

Systemic lupus erythematosus (SLE) is an inflammatory autoimmune disease that affects several organs and systems. Its etiology remains unknown, although it is probably multifactorial. The human leukocyte antigen G (HLA-G) is a nonclassic major histoc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0228f173b3030520887cc10ebc8a8d17
https://doi.org/10.1111/j.1399-0039.2011.01635.x

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Expression of CD55 and CD59 on peripheral blood cells from systemic lupus erythematosus (SLE) patients

Autor: Gustavo Adolpho Moreira Faulhaber, Lucia Mariano da Rocha Silla, Jóice Merzoni, Tamara Mucenic, Ana Paula Alegretti, Ricardo Machado Xavier

Publikováno v: Cellular Immunology. 265:127-132

CD55 and CD59 are glycosylphosphatidylinositol-anchored proteins with complement inhibitory properties. CD55 inhibits the formation of C3 convertases, and CD59 prevents the terminal polymerisation of the membrane attack complex. It has been reported

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f724ec20d4188024214acd49b469c9d1
https://doi.org/10.1016/j.cellimm.2010.07.013

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Mannose-binding lectin gene polymorphisms in Brazilian patients with systemic lupus erythematosus

Autor: J M Z Júnior, José Artur Bogo Chies, Tamara Mucenic, G G Rucatti, Ricardo Machado Xavier, G.K. da Silva, Nadine Glesse, Odirlei André Monticielo, João Carlos Tavares Brenol, B P dos Santos

Publikováno v: Lupus. 19:280-287

The mannose-binding lectin gene (MBL-2) has emerged as a candidate for systemic lupus erythematosus susceptibility, but studies in Brazilian population have not been conducted. To examine potential associations of mannose-binding lectin alleles G57E,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b823d76749d93fdd9cf44a2352e60f9
https://doi.org/10.1177/0961203309351895

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ABCB1 C1236T, G2677T/A and C3435T polymorphisms in systemic lupus erythematosus patients

Autor: Marion Schiengold, Tamara Mucenic, José Artur Bogo Chies, Tatiana Pereira Gonzalez, Ricardo Machado Xavier, João Carlos Tavares Brenol

Publikováno v: Repositório Institucional da UFRGS
Universidade Federal do Rio Grande do Sul (UFRGS)
instacron:UFRGS

P-glycoprotein (Pgp), the ABCB1 gene product, acts as an efflux pump that transports a large variety of substrates and is a mechanism of cell protection against xenobiotics. An increasing number of studies have shown that some ABCB1 polymorphisms may

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::581d152cabf3d63e36088edaf9383c30
https://doi.org/10.1590/s0100-879x2008000900005

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Brazilian Portuguese validation of the Leeds Assessment of Neuropathic Symptoms and Signs for patients with chronic pain

Autor: Betânia Câmara-Ehlers, Osvaldo J. M. Nascimento, Marcia Lorena Fagundes Chaves, Pedro Schestatsky, Michael I. Bennett, Wolnei Caumo, Tamara Mucenic, Vitor Félix-Torres

Publikováno v: Pain medicine (Malden, Mass.). 12(10)

Background. Neuropathic pain (NP) is a very fre- quent and unrecognized condition in clinical prac- tice. Therefore, it is important to have a reliable instrument to assess pain subtypes in various cultures. The Leeds Assessment of Neuropathic Sympto

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f7662209c3386425c03141c2c896859
https://pubmed.ncbi.nlm.nih.gov/21883875

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O papel das proteínas reguladoras do complemento CD55/CD59 em células de sangue periférico de pacientes com lúpus eritematoso sistêmico

Autor: João Carlos Tavares Brenol, Tamara Mucenic, Ana Paula Alegretti, Ricardo Machado Xavier

Publikováno v: Revista Brasileira de Reumatologia v.49 n.3 2009
Revista Brasileira de Reumatologia
Sociedade Brasileira de Reumatologia (SBR)
instacron:SBR
Repositório Institucional da UFRGS
Universidade Federal do Rio Grande do Sul (UFRGS)
instacron:UFRGS
Revista Brasileira de Reumatologia, Volume: 49, Issue: 3, Pages: 276-287, Published: JUN 2009

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5446e3996e6e92fc13f05e0225833f67
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0482-50042009000300009

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