Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Tamar Y, Feinberg"'
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-20 (2022)
Cancer cells and macrophages can infiltrate and remodel the extracellular matrix (ECM). Here, by using native basement membrane-interstitial matrix explants as model and live cell confocal imaging, the authors reveal divergent mechanisms used by canc
Externí odkaz:
https://doaj.org/article/1a7670873a1c4f749a9b3b628cb103ce
Autor:
Shaopeng Yuan, Katherine S. Stewart, Yihao Yang, Merve Deniz Abdusselamoglu, S. Martina Parigi, Tamar Y. Feinberg, Karen Tumaneng, Hanseul Yang, John M. Levorse, Lisa Polak, David Ng, Elaine Fuchs
Publikováno v:
Nature. 612:555-563
Squamous cell carcinomas are triggered by marked elevation of RAS–MAPK signalling and progression from benign papilloma to invasive malignancy1–4. At tumour–stromal interfaces, a subset of tumour-initiating progenitors, the cancer stem cells, o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::425de5bfef61c0d2dc465c1216b9a632
https://doi.org/10.1038/s41586-022-05475-6
https://doi.org/10.1038/s41586-022-05475-6
Publikováno v:
Nature communications. 13(1)
Macrophages and cancer cells populations are posited to navigate basement membrane barriers by either mobilizing proteolytic enzymes or deploying mechanical forces. Nevertheless, the relative roles, or identity, of the proteinase -dependent or -indep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8750faba4c36290c0a9358b14281ad2d
https://pubmed.ncbi.nlm.nih.gov/36302921
https://pubmed.ncbi.nlm.nih.gov/36302921
Autor:
Yi Tang, Farideh Sabeh, John J.G. Tesmer, Stephen J. Weiss, Xiao Yan Li, Tamar Y. Feinberg, Moustafa A. Sakr
Publikováno v:
The Journal of biological chemistry. 293(21)
Following ENU mutagenesis, a phenodeviant line was generated, termed the “Cartoon mouse,” that exhibits profound defects in growth and development. Cartoon mice harbor a single S466P point mutation in the MT1-MMP hemopexin domain, a 200-amino aci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16c39079bfb32fd58c3b3d8c32de408e
https://pubmed.ncbi.nlm.nih.gov/29643184
https://pubmed.ncbi.nlm.nih.gov/29643184