Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Tamar Nethanel"'
Autor:
Tamar Nethanel, Heinz-Peter Nasheuer, Maarit Jokela, Gabriel Kaufmann, Anna K. Rytkönen, Markku Vaara, Raija Sormunen, Tomi Hillukkala, Helmut Pospiech, Juhani E. Syväoja, Miiko Sokka
Publikováno v:
FEBS Journal. 273:5535-5549
DNA polymerase e co-operates with polymerases α and δ in the replicative DNA synthesis of eukaryotic cells. We describe here a specific physical interaction between DNA polymerase e and RNA polymerase II, evidenced by reciprocal immunoprecipitation
Publikováno v:
Scopus-Elsevier
The eukaryal single-stranded DNA binding protein replication protein A (RPA) binds short oligonucleotides with high affinity but exhibits low cooperativity in binding longer templates, opposite to prokaryal counterparts. This discrepancy could reflec
Autor:
T. Zlotkin, M. Y. W. T. Lee, I. Dornreiter, Tamar Nethanel, Gabriel Kaufmann, L. Uitto, J. Syvaoja, E. Fanning, Yunquan Jiang
Publikováno v:
The EMBO Journal. 15:2298-2305
The contributions of DNA polymerases alpha, delta, and epsilon to SV40 and nuclear DNA syntheses were evaluated. Proteins were UV-crosslinked to nascent DNA within replicating chromosomes and the photolabelled polymerases were immunopurified. Only DN
Publikováno v:
Journal of Virology. 66:6634-6640
We have previously proposed that DNA polymerase alpha-primase provides short RNA-DNA precursors below 40 nucleotides (DNA primers), several of which assemble into an Okazaki piece after intervening RNA has been removed and the gaps have been filled b
Autor:
Anna K, Rytkönen, Tomi, Hillukkala, Markku, Vaara, Miiko, Sokka, Maarit, Jokela, Raija, Sormunen, Heinz-Peter, Nasheuer, Tamar, Nethanel, Gabriel, Kaufmann, Helmut, Pospiech, Juhani E, Syväoja
Publikováno v:
The FEBS journal. 273(24)
DNA polymerase epsilon co-operates with polymerases alpha and delta in the replicative DNA synthesis of eukaryotic cells. We describe here a specific physical interaction between DNA polymerase epsilon and RNA polymerase II, evidenced by reciprocal i
Autor:
Markku Vaara, Gabriel Kaufmann, Amal Rahmeh, Anna K. Rytkönen, Helmut Pospiech, Marietta Y.W.T. Lee, Juhani E. Syväoja, Esa Läärä, Heinz-Peter Nasheuer, Raija Sormunen, Tamar Nethanel
Publikováno v:
The FEBS journal. 273(13)
The contributions of human DNA polymerases (pols) alpha, delta and epsilon during S-phase progression were studied in order to elaborate how these enzymes co-ordinate their functions during nuclear DNA replication. Pol delta was three to four times m
Autor:
Gabriel Kaufmann, Tamar Nethanel
Publikováno v:
Progress in Nucleic Acid Research and Molecular Biology Volume 77 ISBN: 9780125400770
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::93dff37005b87e89b4125222da3c8856
https://doi.org/10.1016/s0079-6603(04)77005-1
https://doi.org/10.1016/s0079-6603(04)77005-1
The eukaryotic single-stranded DNA binding protein replication protein A (RPA) participates in major DNA transactions. RPA also interacts through its middle subunit (Rpa2) with regulators of the cell division cycle and of the response to DNA damage.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d552573dccdebe772a53c43331261a8
https://europepmc.org/articles/PMC109225/
https://europepmc.org/articles/PMC109225/
Autor:
Gabriel Kaufmann, Tamar Nethanel
Agents discriminating between DNA polymerase alpha and DNA polymerases of class delta (polymerase delta or epsilon) were used to characterize steps in the synthesis of the lagging DNA strand of simian virus 40 during DNA replication in isolated nucle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::706b8ae0769ca110fad605dcd76e1432
https://europepmc.org/articles/PMC248760/
https://europepmc.org/articles/PMC248760/
Publikováno v:
Journal of Virology. 62:2867-2873
It is generally accepted that an aphidicolin-sensitive DNA polymerase elongates the eucaryotic RNA primer (iRNA) into a mature Okazaki piece reaching ca. 200 nucleotides. Yet, as shown here, nascent DNA chains below 40 nucleotides accumulated in simi