Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Tamar Ginsburg-Shmuel"'
Autor:
Moussa B.H. Youdim, Bilha Fischer, Tali Fishman Jacob, Orly Weinreb, Mudit Dixit, Begoña Fonseca, Jesús Pintor, Tamar Ginsburg-Shmuel, Vijay Singh, Dan Thomas Major
Publikováno v:
Purinergic Signalling. 14:271-284
Extracellular nucleotides can regulate the production/drainage of the aqueous humor via activation of P2 receptors, thus affecting the intraocular pressure (IOP). We evaluated 5-OMe-UDP(α-B), 1A, a potent P2Y6-receptor agonist, for reducing IOP and
Autor:
Djordje Grbic, Bilha Fischer, Guillaume Arguin, Tamar Ginsburg-Shmuel, Michael Haas, Fernand-Pierre Gendron, Yael Nadel, Georg Reiser
Publikováno v:
Bioorganic & Medicinal Chemistry. 20:5483-5495
P2Y(6) nucleotide receptor (P2Y(6)-R) plays important physiological roles, such as insulin secretion and reduction of intraocular pressure. However, this receptor is still lacking potent and selective agonists to be used as potential drugs. Here, we
Publikováno v:
Neuroscience letters. 578
P2Y receptors are activated by nucleotides and involved in numerous physiological/pathophysiological processes. However, investigations of specific P2Y receptor functions have been hampered by lack of suitable receptor agonists–antagonists. Recentl