Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Tamar Getter"'
Publikováno v:
ACS Omega, Vol 9, Iss 44, Pp 44214-44223 (2024)
Externí odkaz:
https://doaj.org/article/89edfecf54fb467ab98079e7a603a68a
Autor:
Eliav Blum, Raanan Margalit, Laura Levy, Tamar Getter, Ron Lahav, Sofia Zilber, Paul Bradfield, Beat A. Imhof, Evgenia Alpert, Arie Gruzman
Publikováno v:
Molecules, Vol 26, Iss 15, p 4583 (2021)
We recently developed a molecule (GT-73) that blocked leukocyte transendothelial migration from blood to the peripheral tissues, supposedly by affecting the platelet endothelial cell adhesion molecule (PECAM-1) function. GT-73 was tested in an LPS-in
Externí odkaz:
https://doaj.org/article/0b2b95f1998749f49ec04d0c7882ccb4
Autor:
Siyun Chen, Tamar Getter, David Salom, Di Wu, Daniel Quetschlich, Dror S. Chorev, Krzysztof Palczewski, Carol V. Robinson
Publikováno v:
Nature. 604:384-390
G protein-coupled receptors (GPCRs) are cell-surface receptors that respond to various stimuli to induce signalling pathways across cell membranes. Recent progress has yielded atomic structures of key intermediates1,2 and roles for lipids in signalli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::496d18adcda35f0e7bd23bc730973a44
https://doi.org/10.1038/s41586-022-04547-x
https://doi.org/10.1038/s41586-022-04547-x
Publikováno v:
The Journal of biological chemistry, vol 297, iss 6
The Journal of Biological Chemistry
The Journal of Biological Chemistry
The elongated cilia of the outer segment of rod and cone photoreceptor cells can contain concentrations of visual pigments of up to 5mM. The rod visual pigments, G protein-coupled receptors called rhodopsins, have a propensity to self-aggregate, a pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f4b6d1767db0f3ad1e56f872518fad7
https://escholarship.org/uc/item/99j7h5nn
https://escholarship.org/uc/item/99j7h5nn
Autor:
Ron Lahav, Evgenia Alpert, Paul F. Bradfield, Laura Levy, Arie Gruzman, Beat A. Imhof, Raanan Margalit, Tamar Getter, Sofia Zilber, Eliav Blum
Publikováno v:
Molecules
Volume 26
Issue 15
Molecules, Vol 26, Iss 4583, p 4583 (2021)
Volume 26
Issue 15
Molecules, Vol 26, Iss 4583, p 4583 (2021)
We recently developed a molecule (GT-73) that blocked leukocyte transendothelial migration from blood to the peripheral tissues, supposedly by affecting the platelet endothelial cell adhesion molecule (PECAM-1) function. GT-73 was tested in an LPS-in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a1271087472173e4e38d87bfc0db80f
Autor:
Susie Suh, Seth Blackshaw, Tamar Getter, Yuanyuan Chen, Xiuli Ma, Zhiqian Dong, Krzysztof Palczewski, James T. Handa, Thanh Hoang
Publikováno v:
Journal of Biological Chemistry. 294:9461-9475
The retinoid cycle is a metabolic process in the vertebrate retina that continuously regenerates 11-cis-retinal (11-cisRAL) from the all-trans-retinal (atRAL) isomer. atRAL accumulation can cause photoreceptor degeneration and irreversible visual dys
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c06f994ffcf14624f9dbe95ecb02d74d
https://doi.org/10.1074/jbc.ra119.008697
https://doi.org/10.1074/jbc.ra119.008697
Autor:
Wenyu Sun, Tivadar Orban, Philip D. Kiser, Songqi Gao, Henri Leinonen, Krzysztof Palczewski, Timothy S. Kern, Hossein Heidari-Torkabadi, Alexander A. Veenstra, Tamar Getter, Zhiqian Dong
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 364:207-220
Degeneration of retinal photoreceptor cells can arise from environmental and/or genetic causes. Since photoreceptor cells, the retinal pigment epithelium (RPE), neurons, and glial cells of the retina are intimately associated, all cell types eventual
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e4ee24e158a44e82b25c272f6c17261
https://doi.org/10.1124/jpet.117.245167
https://doi.org/10.1124/jpet.117.245167
Autor:
Krzysztof Palczewski, Sahil Gulati, Frans Vinberg, Tamar Getter, Yuanyuan Chen, Remy Zimmerman
Publikováno v:
FASEB J
The classic concept that GPCRs function as monomers has been challenged by the emerging evidence of GPCR dimerization and oligomerization. Rhodopsin (Rh) is the only GPCR whose native oligomeric arrangement was revealed by atomic force microscopy dem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27233e8ba70c721bd634f454b2c9f325
https://pubmed.ncbi.nlm.nih.gov/31121099
https://pubmed.ncbi.nlm.nih.gov/31121099
Autor:
Tamar, Getter, Susie, Suh, Thanh, Hoang, James T, Handa, Zhiqian, Dong, Xiuli, Ma, Yuanyuan, Chen, Seth, Blackshaw, Krzysztof, Palczewski
Publikováno v:
J Biol Chem
The retinoid cycle is a metabolic process in the vertebrate retina that continuously regenerates 11-cis-retinal (11-cisRAL) from the all-trans-retinal (atRAL) isomer. atRAL accumulation can cause photoreceptor degeneration and irreversible visual dys
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7ab936a997629eb85069ac4ec9a0776e
https://pubmed.ncbi.nlm.nih.gov/31073029
https://pubmed.ncbi.nlm.nih.gov/31073029
Autor:
Olga Viskind, Arie Gruzman, Hanoch Senderowitz, Susanne Petri, Daniel Offen, Omer Green, Inchan Kwon, Yael Barhum, Simpson Gregoire, Ilana Zaks, Tom Shani, Hugo E. Gottlieb, Tali Ben-Zur, Adrian Israelson, Sebastian Böselt, Tamar Getter, Moran Shubely
Publikováno v:
ChemMedChem. 10:850-861
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by the selective death of motor neurons and skeletal muscle atrophy. The majority of ALS cases are acquired spontaneously, with inherited disease accounting for on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3991251fba6560814288c44bea240a49
https://doi.org/10.1002/cmdc.201500045
https://doi.org/10.1002/cmdc.201500045