Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Tamar Ansbacher"'
Autor:
Matan Gabay, Inbar Stern, Nadya Gruzdev, Adi Cohen, Lucia Adriana-Lifshits, Tamar Ansbacher, Itamar Yadid, Maayan Gal
Publikováno v:
Metabolic Engineering Communications, Vol 18, Iss , Pp e00236- (2024)
Methionine biosynthesis relies on the sequential catalysis of multiple enzymes. Escherichia coli, the main bacteria used in research and industry for protein production and engineering, utilizes the three-step trans-sulfurylation pathway catalyzed by
Externí odkaz:
https://doaj.org/article/e74e3d9244514298b81baef3b4f1230d
Autor:
Tamar Ansbacher, Ran Tohar, Adi Cohen, Orel Cohen, Shifra Levartovsky, Adi Arieli, Shlomo Matalon, Daniel Z. Bar, Maayan Gal, Evgeny Weinberg
Publikováno v:
Journal of Biological Engineering, Vol 17, Iss 1, Pp 1-10 (2023)
Abstract The currently employed tooth extraction methods in dentistry involve mechanical disruption of the periodontal ligament fibers, leading to inevitable trauma to the bundle bone comprising the socket walls. In our previous work, we have shown t
Externí odkaz:
https://doaj.org/article/a26b1952ca664d38ac08be45a0364016
Autor:
Hen Alali, Itai Bloch, Irena Rapaport, Luisa Rodrigues, Inbal Sher, Tamar Ansbacher, Maayan Gal
Publikováno v:
Pharmaceuticals, Vol 15, Iss 6, p 752 (2022)
The initial discovery phase of protein modulators, which consists of filtering molecular libraries and in vitro direct binding validation, is central in drug discovery. Thus, virtual screening of large molecular libraries, together with the evaluatio
Externí odkaz:
https://doaj.org/article/10a97a35fa234feea89f18d6d440c46d
Autor:
Ran Tohar, Hen Alali, Tamar Ansbacher, Tamar Brosh, Inbal Sher, Yossi Gafni, Evgeny Weinberg, Maayan Gal
Publikováno v:
Journal of Functional Biomaterials, Vol 13, Iss 2, p 76 (2022)
Minimally invasive exodontia is among the long-sought-for development aims of safe dental medicine. In this paper, we aim, for the first time, to examine whether the enzymatic disruption of the periodontal ligament fibers reduces the force required f
Externí odkaz:
https://doaj.org/article/c79fd09e4c294b3097567edf65ff0b50
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 16, p 8552 (2021)
Collagenases are essential enzymes capable of digesting triple-helical collagen under physiological conditions. These enzymes play a key role in diverse physiological and pathophysiological processes. Collagenases are used for diverse biotechnologica
Externí odkaz:
https://doaj.org/article/158327bcbfd74ebcb0eb78f55f00d089
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 16
International Journal of Molecular Sciences, Vol 22, Iss 8552, p 8552 (2021)
Volume 22
Issue 16
International Journal of Molecular Sciences, Vol 22, Iss 8552, p 8552 (2021)
Collagenases are essential enzymes capable of digesting triple-helical collagen under physiological conditions. These enzymes play a key role in diverse physiological and pathophysiological processes. Collagenases are used for diverse biotechnologica
Autor:
Neta Nitoker Eliaz, Tamar Ansbacher, Keren Raz, Mor Shimshi, Dan Thomas Major, Susanta Das, Anil R. Mhashal
Publikováno v:
Journal of Chemical Theory and Computation. 15:5116-5134
Enzymes play a pivotal role in all biological systems. These biomachines are the most effective catalysts known, dramatically enhancing the rate of reactions by more than 10 orders of magnitude relative to the uncatalyzed reactions in solution. Predi
Publikováno v:
Biochemistry. 57:3773-3779
Taxadiene synthase (TXS) catalyzes the formation of natural product taxa-4(5),11(12)-diene (henceforth taxadiene). Taxadiene is the precursor in the formation of Taxol, which is an important natural anticancer agent. In the current study, we present
Publikováno v:
ACS Catalysis. 7:7653-7657
Enzymes are highly efficient and usually very specific biocatalysts. However, some enzyme families, such as terpene synthases, are inherently promiscuous due to the extremely challenging chemistry they have evolved to tackle. Here we focus on one suc
Autor:
Yong Yang, Chun-Chi Chen, Zhenying Chang, Guimin Zhang, Dan Thomas Major, Jian-Wen Huang, Tamar Ansbacher, Longhai Dai, Lilan Zhang, Weidong Liu, Rey-Ting Guo, Tzu Ping Ko
Publikováno v:
Organicbiomolecular chemistry. 17(8)
LepI is a novel multifunctional enzyme that catalyzes stereoselective dehydration, Diels-Alder reaction, and retro-Claisen rearrangement. Here we report the crystal structure of LepI in complex with its co-factor S-adenosyl methionine (SAM). LepI for