Zobrazeno 1 - 10
of 231
pro vyhledávání: '"Tamar, Geiger"'
Autor:
Avishai Maliah, Nadine Santana-Magal, Shivang Parikh, Sagi Gordon, Keren Reshef, Yuval Sade, Aseel Khateeb, Alon Richter, Amit Gutwillig, Roma Parikh, Tamar Golan, Matan Krissi, Manho Na, Gal Binshtok, Paulee Manich, Nadav Elkoshi, Sharon Grisaru-Tal, Valentina Zemser-Werner, Ronen Brenner, Hananya Vaknine, Eran Nizri, Lilach Moyal, Iris Amitay-Laish, Luiza Rosemberg, Ariel Munitz, Noga Kronfeld-Schor, Eric Shifrut, Oren Kobiler, Asaf Madi, Tamar Geiger, Yaron Carmi, Carmit Levy
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract T cell inhibitory mechanisms prevent autoimmune reactions, while cancer immunotherapy aims to remove these inhibitory signals. Chronic ultraviolet (UV) exposure attenuates autoimmunity through promotion of poorly understood immune-suppressiv
Externí odkaz:
https://doaj.org/article/558f6188a6ba4158b35fee08d311324d
Autor:
Adi Amar-Schwartz, Vered Ben Hur, Amina Jbara, Yuval Cohen, Georgina D Barnabas, Eliran Arbib, Zahava Siegfried, Bayan Mashahreh, Fouad Hassouna, Asaf Shilo, Mohammad Abu-Odeh, Michael Berger, Reuven Wiener, Rami Aqeilan, Tamar Geiger, Rotem Karni
Publikováno v:
eLife, Vol 11 (2022)
The mTORC1 substrate, S6 Kinase 1 (S6K1), is involved in the regulation of cell growth, ribosome biogenesis, glucose homeostasis, and adipogenesis. Accumulating evidence has suggested a role for mTORC1 signaling in the DNA damage response. This is mo
Externí odkaz:
https://doaj.org/article/415f0119bfe2430898b264371e2f1a67
Autor:
Lee Shaashua, Anabel Eckerling, Boaz Israeli, Gali Yanovich, Ella Rosenne, Suzana Fichman-Horn, Ido Ben Zvi, Liat Sorski, Rita Haldar, Ronit Satchi-Fainaro, Tamar Geiger, Erica K. Sloan, Shamgar Ben-Eliyahu
Publikováno v:
BMC Biology, Vol 18, Iss 1, Pp 1-4 (2020)
An amendment to this paper has been published and can be accessed via the original article.
Externí odkaz:
https://doaj.org/article/c9b0dca7b1d046a3a5d62b7a10e5f3c3
Autor:
Lee Shaashua, Anabel Eckerling, Boaz Israeli, Gali Yanovich, Ella Rosenne, Suzana Fichman-Horn, Ido Ben Zvi, Liat Sorski, Rita Haldar, Ronit Satchi-Fainaro, Tamar Geiger, Erica K. Sloan, Shamgar Ben-Eliyahu
Publikováno v:
BMC Biology, Vol 18, Iss 1, Pp 1-13 (2020)
Abstract Background Numerous case studies have reported spontaneous regression of recognized metastases following primary tumor excision, but underlying mechanisms are elusive. Here, we present a model of regression and latency of metastases followin
Externí odkaz:
https://doaj.org/article/c428b1582c5b452882d00c864c28dd9b
Autor:
Yael Elbaz-Alon, Yuting Guo, Nadav Segev, Michal Harel, Daniel E. Quinnell, Tamar Geiger, Ori Avinoam, Dong Li, Jodi Nunnari
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Membrane contact sites between organelles have been shown to play important biological roles. Here, the authors show that at the ER, PDZD8 associates with Protrudin and also with Rab7 endosomes and recruits mitochondria to form three-way contacts.
Externí odkaz:
https://doaj.org/article/707039eaf48b40168be3bf1f7653eaa0
Autor:
Navin Varadarajan, Patrick Hwu, Cara Haymaker, Chantale Bernatchez, Caitlin Creasy, Scott Woodman, Jay R Adolacion, Michal Harel, Xingyue An, Melisa Angela Paniagua, Mohsen Fathi, Ali Rezvan, Tamar Geiger, Jonathan Robinson, Amit Amritkar
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
Externí odkaz:
https://doaj.org/article/13987a175a3747d38d99f008bee3d7cf
Autor:
Polina Denichenko, Maxim Mogilevsky, Antoine Cléry, Thomas Welte, Jakob Biran, Odelia Shimshon, Georgina D. Barnabas, Miri Danan-Gotthold, Saran Kumar, Eylon Yavin, Erez Y. Levanon, Frédéric H. Allain, Tamar Geiger, Gil Levkowitz, Rotem Karni
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Alternative splicing, critical for gene expression, is deregulated in many diseases. Here the authors develop decoy oligonucleotides to specifically downregulate splicing factors activity.
Externí odkaz:
https://doaj.org/article/56b48a0782e64173831607d2f384bb24
Autor:
Ettai Markovits, Ortal Harush, Erez N. Baruch, Eldad D. Shulman, Assaf Debby, Orit Itzhaki, Liat Anafi, Artem Danilevsky, Noam Shomron, Guy Ben-Betzalel, Nethanel Asher, Ronnie Shapira-Frommer, Jacob Schachter, Iris Barshack, Tamar Geiger, Ran Elkon, Michal J. Besser, Gal Markel
Publikováno v:
Cancer Immunology Research. :OF1-OF16
Immunotherapy has revolutionized the treatment of advanced melanoma. Because the pathways mediating resistance to immunotherapy are largely unknown, we conducted transcriptome profiling of preimmunotherapy tumor biopsies from patients with melanoma t
Autor:
Anjana Shenoy, Nishanth Belugali Nataraj, Gili Perry, Fabricio Loayza Puch, Remco Nagel, Irina Marin, Nora Balint, Noa Bossel, Anya Pavlovsky, Iris Barshack, Bella Kaufman, Reuven Agami, Yosef Yarden, Maya Dadiani, Tamar Geiger
Publikováno v:
Molecular Systems Biology, Vol 16, Iss 9, Pp n/a-n/a (2020)
Abstract Tumor relapse as a consequence of chemotherapy resistance is a major clinical challenge in advanced stage breast tumors. To identify processes associated with poor clinical outcome, we took a mass spectrometry‐based proteomic approach and
Externí odkaz:
https://doaj.org/article/5c738af05ac8485a9c300273476af2be
Autor:
Kobi Perl, Kathy Ushakov, Yair Pozniak, Ofer Yizhar-Barnea, Yoni Bhonker, Shaked Shivatzki, Tamar Geiger, Karen B. Avraham, Ron Shamir
Publikováno v:
BMC Genomics, Vol 18, Iss 1, Pp 1-14 (2017)
Abstract Background The quantitative relations between RNA and protein are fundamental to biology and are still not fully understood. Across taxa, it was demonstrated that the protein-to-mRNA ratio in steady state varies in a direction that lessens t
Externí odkaz:
https://doaj.org/article/9df7bd0206664029bc89d15343d4f5e2