Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Tamanna Saiyed"'
Autor:
Kaiseal T. G. Sarson-Lawrence, Joshua M. Hardy, Josephine Iaria, Dina Stockwell, Kira Behrens, Tamanna Saiyed, Cyrus Tan, Leila Jebeli, Nichollas E. Scott, Toby A. Dite, Nicos A. Nicola, Andrew P. Leis, Jeffrey J. Babon, Nadia J. Kershaw
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Thrombopoietin (Tpo) is the primary regulator of megakaryocyte and platelet numbers and is required for haematopoetic stem cell maintenance. Tpo functions by binding its receptor (TpoR, a homodimeric Class I cytokine receptor) and initiating
Externí odkaz:
https://doaj.org/article/90ff36cf97bf40a595fd54f4fb808af6
Autor:
Rhiannon Morris, Narelle Keating, Cyrus Tan, Hao Chen, Artem Laktyushin, Tamanna Saiyed, Nicholas P. D. Liau, Nicos A. Nicola, Tony Tiganis, Nadia J. Kershaw, Jeffrey J. Babon
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-11 (2023)
Abstract Protein Tyrosine Phosphatase 1B (PTP1B) is the prototypical protein tyrosine phosphatase and plays an essential role in the regulation of several kinase-driven signalling pathways. PTP1B displays a preference for bisphosphorylated substrates
Externí odkaz:
https://doaj.org/article/fe7ce3bae9694500a0f1ccbffabd3899
Autor:
David A. Dougan, Liz J. Valente, Hanmiao Zhan, Kornelius Zeth, Lauren M. Angley, Kaye N. Truscott, Erica J. Brodie, Matthew A. Perugini, Tamanna Saiyed, Philip R. Strack, Verena J. Schuenemann, Bradley R. Lowth
Publikováno v:
Communications Biology
Communications Biology, Vol 3, Iss 1, Pp 1-12 (2020)
Communications Biology, Vol 3, Iss 1, Pp 1-12 (2020)
Over a decade ago Polymerase δ interacting protein of 38 kDa (PDIP38) was proposed to play a role in DNA repair. Since this time, both the physiological function and subcellular location of PDIP38 has remained ambiguous and our present understanding
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::268286000ae69942bf783893373d2f99
http://europepmc.org/articles/PMC7647994
http://europepmc.org/articles/PMC7647994
Publikováno v:
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-11 (2018)
Scientific Reports, Vol 8, Iss 1, Pp 1-11 (2018)
The maintenance of mitochondrial protein homeostasis (proteostasis) is crucial for correct cellular function. Recently, several mutations in the mitochondrial protease CLPP have been identified in patients with Perrault syndrome 3 (PRLTS3). These mut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f2e8e2df0c6dcc585979115cdac4e21
https://doi.org/10.1038/s41598-018-30311-1
https://doi.org/10.1038/s41598-018-30311-1
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 28(4)
Mutations in succinate dehydrogenase (SDH) subunits and assembly factors cause a range of clinical conditions. One such condition, hereditary paraganglioma 2 (PGL2), is caused by a G78R mutation in the assembly factor SDH5. Although SDH5(G78R) is def
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cfae26150f995693d55583587f0f137
https://pubmed.ncbi.nlm.nih.gov/24414418
https://pubmed.ncbi.nlm.nih.gov/24414418