Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Tamami Fujiki"'
Autor:
Nobuhisa Morimoto, Takayasu Mori, Shingo Shioji, Towako Taguchi, Hatsumi Watanabe, Keigo Sakai, Katsuo Mori, Ayumi Yamamura, Asami Hanioka, Yuichiro Akagi, Tamami Fujiki, Shintaro Mandai, Yutaro Mori, Fumiaki Ando, Koichiro Susa, Soichiro Iimori, Shotaro Naito, Eisei Sohara, Kenichi Ohashi, Shinichi Uchida
Publikováno v:
BMC Nephrology, Vol 24, Iss 1, Pp 1-9 (2023)
Abstract Background As messenger RNA (mRNA)-based vaccines for coronavirus disease 2019 (COVID-19) have been administered to millions of individuals worldwide, cases of de novo and relapsing glomerulonephritis after mRNA COVID-19 vaccination are incr
Externí odkaz:
https://doaj.org/article/f877adac4c2945cbb0eb5679ab5e0cdc
Autor:
Soichiro Suzuki, Fumiaki Ando, Sae Kitagawa, Yu Hara, Tamami Fujiki, Shintaro Mandai, Koichiro Susa, Takayasu Mori, Eisei Sohara, Tatemitsu Rai, Shinichi Uchida
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-14 (2023)
ZNF185 is identified as a novel PKA substrate and found to be important for the organization of endothelial cell–cell junctions and suppression of vascular hyperpermeability by regulating the cAMP/PKA/RhoA signaling pathway.
Externí odkaz:
https://doaj.org/article/8f63103e0820459da3615d3e0e88138a
Autor:
Takaaki Koide, Shintaro Mandai, Reo Kitaoka, Hisazumi Matsuki, Motoko Chiga, Kouhei Yamamoto, Kotaro Yoshioka, Yohsuke Yagi, Soichiro Suzuki, Tamami Fujiki, Fumiaki Ando, Takayasu Mori, Koichiro Susa, Soichiro Iimori, Shotaro Naito, Eisei Sohara, Tatemitsu Rai, Takanori Yokota, Shinichi Uchida
Publikováno v:
Circulation Research. 132:415-431
Background: Chronic kidney disease (CKD) accelerates vascular calcification via phenotypic switching of vascular smooth muscle cells (VSMCs). We investigated the roles of circulating small extracellular vesicles (sEVs) between the kidneys and VSMCs a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d57e0073849e539448ddca1e76b3c193
https://doi.org/10.1161/circresaha.122.321939
https://doi.org/10.1161/circresaha.122.321939
Autor:
Hisazumi Matsuki, Taku Genma, Shintaro Mandai, Tamami Fujiki, Yutaro Mori, Fumiaki Ando, Takayasu Mori, Koichiro Susa, Soichiro Iimori, Shotaro Naito, Eisei Sohara, Tatemitsu Rai, Kiyohide Fushimi, Shinichi Uchida
Publikováno v:
Hypertension (0194911X); Dec2023, Vol. 80 Issue 12, p2591-2600, 10p
Autor:
Nobuhisa Morimoto, Takayasu Mori, Shingo Shioji, Hatsumi Watanabe, Keigo Sakai, Katsuo Mori, Ayumi Yamamura, Asami Hanioka, Yuichiro Akagi, Tamami Fujiki, Shintaro Mandai, Yutaro Mori, Fumiaki Ando, Koichiro Susa, Soichiro Iimori, Shotaro Naito, Eisei Sohara, Shinichi Uchida
Publikováno v:
International Journal of Rheumatic Diseases.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f25347332eec98d9cae3b02840f87771
https://doi.org/10.1111/1756-185x.14645
https://doi.org/10.1111/1756-185x.14645
Autor:
Yuta Nakano, Koichiro Susa, Tomoki Yanagi, Yuichi Hiraoka, Takefumi Suzuki, Takayasu Mori, Fumiaki Ando, Shintaro Mandai, Tamami Fujiki, Tatemitsu Rai, Shinichi Uchida, Eisei Sohara
Publikováno v:
In Vitro Cellular & Developmental Biology - Animal. 58:85-95
CRISPR/Cas9 genome editing underwent remarkable progress and significantly contributed to the development of life sciences. Induced pluripotent stem cells (iPSCs) have also made a relevant contribution to regenerative medicine, pharmacological resear
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5517d6e91c7ce0492fb77919976ea406
https://doi.org/10.1007/s11626-022-00655-0
https://doi.org/10.1007/s11626-022-00655-0
Absence of ULK1 decreases AMPK activity in the kidney, leading to chronic kidney disease progression
Autor:
Tomoki Yanagi, Hiroaki Kikuchi, Koichiro Susa, Naohiro Takahashi, Hiroki Bamba, Takefumi Suzuki, Yuta Nakano, Tamami Fujiki, Yutaro Mori, Fumiaki Ando, Shintaro Mandai, Takayasu Mori, Koh Takeuchi, Shinya Honda, Satoru Torii, Shigeomi Shimizu, Tatemitsu Rai, Shinichi Uchida, Eisei Sohara
Publikováno v:
Genes to cells : devoted to molecularcellular mechanismsREFERENCES.
AMP-activated protein kinase (AMPK) inactivation in chronic kidney disease (CKD) leads to energy status deterioration in the kidney, constituting the vicious cycle of CKD exacerbation. Unc-51-like kinase 1 (ULK1) is considered a downstream molecule o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aadaba469d69d45dc5f7b6727b547b9a
https://pubmed.ncbi.nlm.nih.gov/36318474
https://pubmed.ncbi.nlm.nih.gov/36318474
Autor:
Yu Hara, Fumiaki Ando, Daisuke Oikawa, Koichiro Ichimura, Hideki Yanagawa, Yuriko Sakamaki, Azuma Nanamatsu, Tamami Fujiki, Shuichi Mori, Soichiro Suzuki, Naofumi Yui, Shintaro Mandai, Koichiro Susa, Takayasu Mori, Eisei Sohara, Tatemitsu Rai, Mikiko Takahashi, Sei Sasaki, Hiroyuki Kagechika, Fuminori Tokunaga, Shinichi Uchida
Publikováno v:
Proceedings of the National Academy of Sciences. 119
Protein kinase A (PKA) directly phosphorylates aquaporin-2 (AQP2) water channels in renal collecting ducts to reabsorb water from urine for the maintenance of systemic water homeostasis. More than 50 functionally distinct PKA-anchoring proteins (AKAP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2950337696c57ce850895fedc0dfd68e
https://doi.org/10.1073/pnas.2202125119
https://doi.org/10.1073/pnas.2202125119
Deletion of Alox15 improves kidney dysfunction and inhibits fibrosis by increased PGD2 in the kidney
Autor:
Fumiaki Ando, Tamami Fujiki, Takuya Fujimaru, Taisuke Furusho, Ayaka Usui, Tomoki Yanagi, Koichiro Susa, Makoto Arita, Hiroaki Kikuchi, Takayasu Mori, Kenichi Asano, Kouhei Yamamoto, Eisei Sohara, Naohiro Takahashi, Yoshiaki Matsuura, Tatemitsu Rai, Shinichi Uchida, Shintaro Mandai
Publikováno v:
Clinical and Experimental Nephrology. 25:445-455
Background Lipid-metabolizing enzymes and their metabolites affect inflammation and fibrosis, but their roles in chronic kidney disease (CKD) have not been completely understood. Methods To clarify their role in CKD, we measured the mRNA levels of ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::93cc54d55aed57bbcc6c63b9dcf5d554
https://doi.org/10.1007/s10157-021-02021-y
https://doi.org/10.1007/s10157-021-02021-y
Autor:
Soichiro Suzuki, Fumiaki Ando, Sae Kitagawa, Yu Hara, Tamami Fujiki, Shintaro Mandai, Koichiro Susa, Takayasu Mori, Eisei Sohara, Tatemitsu Rai, Shinichi Uchida
Signaling through cyclic adenosine monophosphate (cAMP)/protein kinase A (PKA) promotes endothelial barrier function to prevent plasma leakage induced by inflammatory mediators. The discovery of novel PKA substrates in endothelial cells has increased
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4aade439a08d62c6641e015df8a309b
https://doi.org/10.21203/rs.3.rs-1686698/v1
https://doi.org/10.21203/rs.3.rs-1686698/v1
