Výsledky vyhledávání - "Tamako Takagi"

Interferon-associated retinopathy in a uniform regimen of natural interferon-α therapy for chronic hepatitis C

Autor: Yoshihisa Oguchi, Yoshimasa Saito, Mitsuyasu Nakamura, Hiromasa Ishii, Hiroshi Nagata, Tamako Takagi, Hirotoshi Ebinuma, Yasutaka Inagaki, Hiroshi Katsura, Kanji Wakabayashi, Hidetsugu Saito

Publikováno v: Liver. 21:192-197

BACKGROUND/AIMS The development of retinal lesions induced by a uniform regimen of interferon-alpha therapy for chronic hepatitis C was prospectively investigated. METHODS Eighty-one patients received 6 mega units of natural interferon-alpha intramus

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e8086c525d1177aeb1624489c4fd5ba7
https://doi.org/10.1034/j.1600-0676.2001.021003192.x

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Reduction of telomerase activity in human liver cancer cells by a histone deacetylase inhibitor

Autor: Yoshimasa Saito, Kanji Wakabayashi, Hidetsugu Saito, Hirotoshi Ebinuma, Tamako Takagi, Mitsuyasu Nakamura, Hiromasa Ishii, Nobuhiro Nakamoto

Publikováno v: Journal of Cellular Physiology. 187:392-401

The presence of telomerase has been demonstrated recently in many different malignancies. Several reports documented that in human hepatocellular carcinoma, the level of telomerase activity parallels its differentiation stage. In the present study, t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa69b4e7ff7f878b43e8decc3d1035f6
https://doi.org/10.1002/jcp.1087

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Effect of the molar ratio of branched-chain to aromatic amino acids on growth and albumin mRNA expression of human liver cancer cell lines in a serum-free medium

Autor: Tamako Takagi, Hirotoshi Ebinuma, Hiromasa Ishii, Kanji Wakabayashi, Yoshimasa Saito, Mitsuyasu Nakamura, Hidetsugu Saito

Publikováno v: Nutrition and cancer. 39(1)

Supplementation of branched-chain amino acids (BCAAs) is often used for the treatment of hepatic encephalopathy and low albuminemia in Japan. In this scenario, although many cases are complicated with hepatocellular carcinoma in chronic viral infecti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44c543228090acbb6c350e6f3316f996
https://pubmed.ncbi.nlm.nih.gov/11588894

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Interferon regulatory factor 1 promoter polymorphism and response to type 1 interferon

Autor: Shinichiro Tada, Kanji Wakabayashi, Yoshimasa Saito, Nobuhiro Nakamoto, Hidetsugu Saito, Satoshi Kurita, Tamako Takagi, Hirotoshi Ebinuma, Hiromasa Ishii

Publikováno v: Journal of cellular biochemistry. Supplement.

The clinical success of interferon-treatment has been found to vary in different individuals. To explain this, we hypothesized that responses to type 1 interferons could be partly determined by interferon regulatory factor-1 gene transcription, becau

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10bde8c3d475d2385892123d0e39b770
https://pubmed.ncbi.nlm.nih.gov/11455584

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Reduction of c-myc expression by an antisense approach under Cre/loxP switching induces apoptosis in human liver cancer cells

Autor: Motomichi Kosuga, Hidetsugu Saito, Yoshimasa Saito, Hirotoshi Ebinuma, Kanji Wakabayashi, Hiromasa Ishii, Torayuki Okuyama, Tamako Takagi, Nobuhiro Nakamoto

Publikováno v: Journal of cellular physiology. 188(1)

c-Myc has been documented to be both a positive and a negative signal for the induction of apoptosis. It is well known that overexpression of the c-myc gene induces apoptosis of normal cells, but the result of a reduction in its expression is not ful

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3f277fc4ad1e0876d6508fae4c2adbc
https://pubmed.ncbi.nlm.nih.gov/11382922

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Growth Inhibition of Hepatoma Cells by Type 1 Interferons: Modification by Mutations in the Interferon Regulatory Factor-1 Gene

Autor: Hlromasa Ishii, Kanji Wakabayashi, Hidetsugu Saito, Tamako Takagi, Nobuhiro Nakamoto, Satoshi Kurita, Shinichiro Tada

Publikováno v: Trends in Gastroenterology and Hepatology ISBN: 9784431679936

Interferon regulatory factor-1 is an important transcription factor in the interferon system. We have demonstrated that the growth inhibitory effect of type 1 interferons on human hepatoma cells correlates with levels of transcription of the interfer

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::02c3e161dd23ab89e51f32adbe5dc44c
https://doi.org/10.1007/978-4-431-67895-3_26

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Autor: Mitsuyasu Nakamura, Hirotoshi Ebinuma, Tamako Takagi, Jun-ichi Hata, Yoshimasa Saito, Akihiro Umezawa, Hidetsugu Saito, Hiromasa Ishii, Kanji Wakabayashi

Publikováno v: Oncology reports. 7(2)

Expression of the Bcl-2 family members in a human hepatocellular carcinoma cell line (HCC-T) after sodium butyrate-treatment was investigated. Sodium butyrate, a histone deacetylase inhibitor, induced differentiation of the cell line into its normal

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97b66e0f820f1104a492cf4c09aab122
https://pubmed.ncbi.nlm.nih.gov/10671672

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