Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Tamaki Miyazaki"'
Autor:
Daisuke Ando, Megumi Miyatsuji, Hideyuki Sakoda, Eiichi Yamamoto, Tamaki Miyazaki, Tatsuo Koide, Yoji Sato, Ken-ichi Izutsu
Publikováno v:
Pharmaceutics, Vol 16, Iss 2, p 200 (2024)
Dissolving microneedles (MNs) are novel transdermal drug delivery systems that can be painlessly self-administered. This study investigated the effects of experimental conditions on the mechanical characterization of dissolving MNs for quality evalua
Externí odkaz:
https://doaj.org/article/ff9c2ea2ed1c4514bf9152f9196518f0
Publikováno v:
YAKUGAKU ZASSHI. 142:65-74
The crystallization of active pharmaceutical ingredients (APIs) in matrix-type transdermal patches has implications for the rate of drug absorption through the skin and patch adhesion strength. Therefore, the presence or absence and the degree of API
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b996bdc1a680ce29302108986ea3e5d
https://doi.org/10.1248/yakushi.21-00160
https://doi.org/10.1248/yakushi.21-00160
Autor:
Eiichi Yamamoto, Noriko Tominaga, Hitomi Kan-no, Daisuke Ando, Tamaki Miyazaki, Ken-ichi Izutsu
Publikováno v:
Pharmaceutical Research. 38:2167-2177
Undesired drug sorption on laboratory material surfaces reduces the performance of analytical methods and results in the generation of unreliable data. Hence, we characterized the sorption of drugs and evaluated the sorption extent using a linear fre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::890e17b8b75074bf549735d6d7041d91
https://doi.org/10.1007/s11095-021-03156-z
https://doi.org/10.1007/s11095-021-03156-z
Publikováno v:
Drug Delivery and Translational Research. 12:426-434
The purpose of this study was to develop a quality evaluation method for dissolving microneedle arrays (DMNAs) and determine the spatial distribution pattern of drugs in DMNAs. Raman spectroscopy mapping was used to visualize the drug distribution in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5542262e5fe7f6b0867ab7f1edd3423
https://doi.org/10.1007/s13346-021-01052-y
https://doi.org/10.1007/s13346-021-01052-y
Autor:
Yuta Amano, Takashi Misawa, Tamaki Miyazaki, Daisuke Ando, Tatsuo Koide, Ken-ichi Izutsu, Hideko Kanazawa, Kenjiro Hanaoka, Eiichi Yamamoto
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 226:115248
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::97a27831a0efe62d8d7ca98640ab9e44
https://doi.org/10.1016/j.jpba.2023.115248
https://doi.org/10.1016/j.jpba.2023.115248
Publikováno v:
International Journal of Pharmaceutics. 626:122158
Amorphization is a powerful approach for improving the aqueous solubility and bioavailability of poorly water-soluble compounds. However, it can cause chemical and physical instability, the latter of which can lead to crystallization during storage,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98b92b6372ff2138431718bcd83a1136
https://doi.org/10.1016/j.ijpharm.2022.122158
https://doi.org/10.1016/j.ijpharm.2022.122158
Publikováno v:
SSRN Electronic Journal.
N -nitrosodimethylamine (NDMA) contamination in several drugs has been reported since 2018, and there is also a potential risk of the NDMA contamination in various other drug substances and their pharmaceutical products. To quantitate NDMA in various
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::75abb18ce7bd723b91667da61d94916d
https://doi.org/10.2139/ssrn.3937790
https://doi.org/10.2139/ssrn.3937790
Publikováno v:
AAPS PharmSciTech. 21
The objective of this study was to develop a simpler and more practical quantitative evaluation method of cold flow (CF) in transdermal drug delivery systems (TDDSs). CF was forcibly induced by loading a weight on a punched-out sample (bisoprolol and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43e23b89cb81497fdc0687a9b2c4ff21
https://doi.org/10.1208/s12249-020-01661-9
https://doi.org/10.1208/s12249-020-01661-9
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 210:114561
N-Nitrosodimethylamine (NDMA) has been detected in some drug substances and pharmaceutical products containing sartans, ranitidine and metformin, and a potential risk of NDMA contamination exists in other drug substances and their pharmaceutical prod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80c3d1bae856c7014d4dc54816c58370
https://doi.org/10.1016/j.jpba.2021.114561
https://doi.org/10.1016/j.jpba.2021.114561
Publikováno v:
YAKUGAKU ZASSHI. 138:1425-1433
Forty-four brands of transdermal patches for twelve kinds of active pharmaceutical ingredients (APIs) are available in Japan as of April 30, 2018. Although approximately one-third of the corresponding pharmaceutical interview forms lack information o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8ff484ae5caeabdbedafb31f4b51179
https://doi.org/10.1248/yakushi.18-00117
https://doi.org/10.1248/yakushi.18-00117