Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Tamaki Mabuchi"'
Autor:
Emiko Okuda-Ashitaka, Tayo Katano, Seiji Ito, Shunji Kunori, Tadashi Yamamoto, Shinji Matsumura, Tamaki Mabuchi, Masahiko Watanabe, Tetsuya Abe, Takanobu Nakazawa
Publikováno v:
European Journal of Neuroscience. 32:798-810
Ca(2+) /calmodulin-dependent protein kinase II (CaMKII) is a key mediator of long-term potentiation (LTP), which can be triggered by N-methyl-d-aspartate (NMDA) receptor-mediated Ca(2+) influx. We previously demonstrated that Fyn kinase-mediated phos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::87f41a61b9ca61bba6e4bdcccbdece7c
https://doi.org/10.1111/j.1460-9568.2010.07348.x
https://doi.org/10.1111/j.1460-9568.2010.07348.x
Autor:
Tamaki Mabuchi, Masaaki Suzuki, Masahide Maeda, Toshiaki Minami, Shinichi Tatsumi, Seiji Ito, Masako Soen, Kyoji Furuta
Publikováno v:
European Journal of Pharmacology. 575:75-81
In spite of prominent progress in basic pain research, neuropathic pain remains a significant medical problem, because it is often poorly relieved by conventional analgesics. Thus this situation encourages us to make more sophisticated efforts toward
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b912adc897bb1dfd68e82fad4f2264f1
https://doi.org/10.1016/j.ejphar.2007.07.069
https://doi.org/10.1016/j.ejphar.2007.07.069
Autor:
Tamaki Mabuchi, Atsushi Sasaki, Seiji Ito, Kenichi Serizawa, Ichiro Takasaki, Tsugunobu Andoh, Kimiyasu Shiraki, Yasushi Kuraishi
Publikováno v:
Neuroscience. 150:459-466
We investigated using the mice role of nitric oxide synthase (NOS) in the spinal dorsal horn in herpetic and postherpetic pain, especially allodynia, which was induced by transdermal inoculation of the hind paw with herpes simplex virus type-1 (HSV-1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21ec37443282880544be1e20ff8b600f
https://doi.org/10.1016/j.neuroscience.2007.09.067
https://doi.org/10.1016/j.neuroscience.2007.09.067
Autor:
Emiko Okuda-Ashitaka, Tamaki Mabuchi, Masayoshi Mishina, Seiji Ito, Kenji Sakimura, Tayo Katano, Shinji Matsumura, Li Xu
Publikováno v:
Nitric Oxide. 17:18-24
We have recently demonstrated that nitric oxide (NO) produced by neuronal NO synthase (nNOS) in the spinal cord is involved in the maintenance of neuropathic pain. To clarify whether NO itself affected nNOS activity in the spinal cord as a retrograde
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b89fe14e7f726af664ac455d9d887fe
https://doi.org/10.1016/j.niox.2007.04.004
https://doi.org/10.1016/j.niox.2007.04.004
Autor:
Tamaki Mabuchi, Masayoshi Mishina, Shinji Matsumura, Li Xu, Shindou Okamoto, Emiko Okuda-Ashitaka, Seiji Ito, Kenji Sakimura
Publikováno v:
Neuropharmacology. 52:1318-1325
Nociceptin/orphanin FQ (N/OFQ) was earlier shown to be involved in the maintenance of neuropathic pain by activating neuronal nitric oxide synthase (nNOS). We recently established an ex vivo system to elucidate biochemical and molecular mechanisms fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03a44d5211111a054352faea38bf5892
https://doi.org/10.1016/j.neuropharm.2007.01.013
https://doi.org/10.1016/j.neuropharm.2007.01.013
Publikováno v:
Journal of Neuroscience Methods. 150:174-184
NADPH-diaphorase (NADPH-d) histochemistry has provided a simple method to stain neuronal nitric oxide synthase (nNOS)-containing neurons in the central nervous system. In the spinal cord, NO formation following activation of N -methyl- d -asparate (N
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::397dc072f81b12b62240608c91c3967a
https://doi.org/10.1016/j.jneumeth.2005.06.017
https://doi.org/10.1016/j.jneumeth.2005.06.017
Autor:
Masayoshi Mishina, Tamaki Mabuchi, Tetsuya Abe, Takeshi Yagi, Akitsugu Yamamoto, Tadashi Yamamoto, Takanobu Nakazawa, Seiji Ito, Tayo Katano, Kotaro Hattori, Kunio Takagi, Yoshihide Nakai, Li Xu, Masahiko Watanabe, Shinji Matsumura
Publikováno v:
European Journal of Neuroscience. 22:1445-1454
Despite abundant evidence implicating the importance of N-methyl-D-aspartate (NMDA) receptors in the spinal cord for pain transmission, the signal transduction coupled to NMDA receptor activation is largely unknown for the neuropathic pain state that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::718d24d441e549787bbb07a2c6adcbf8
https://doi.org/10.1111/j.1460-9568.2005.04340.x
https://doi.org/10.1111/j.1460-9568.2005.04340.x
Autor:
Tetsuya Abe, Tayo Katano, Yasuharu Sasaki, Seiji Ito, Shinichi Tatsumi, Toshiaki Minami, Hiroyoshi Hidaka, Shinji Matsumura, Tamaki Mabuchi, Masaaki Suzuki
Publikováno v:
Neuroscience. 131:491-498
Myristoylated alanine-rich C-kinase substrate (MARCKS) is a major in vivo substrate for protein kinase C in the brain and has been implicated in cellular processes associated with cytoskeletal restructuring such as synaptic trafficking and neurotrans
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d9f52bf0b31f364b607518136db9f35
https://doi.org/10.1016/j.neuroscience.2004.10.022
https://doi.org/10.1016/j.neuroscience.2004.10.022
Publikováno v:
Neuroscience Letters. 370:130-134
Neuropathic pain arising from peripheral nerve injury is a clinical disorder characterized by a combination of spontaneous pain, hyperalgesia and tactile pain (allodynia), and remains a significant clinical problem since it is often poorly relieved b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b4d327fb3ec3f052a07e23c3f8293e4
https://doi.org/10.1016/j.neulet.2004.08.043
https://doi.org/10.1016/j.neulet.2004.08.043
Autor:
Shinji Matsumura, Seiji Ito, Norihito Shintani, Hitoshi Hashimoto, Toshiaki Minami, Emiko Okuda-Ashitaka, Tamaki Mabuchi, Tadatoshi Muratani, Akemichi Baba
Publikováno v:
The Journal of Neuroscience. 24:7283-7291
The prolonged sensitization of pain transmission after nerve injury by increasing excitability of spinal neurons and thereby promoting repair is an adaptive response of the body. The neuropeptide pituitary adenylate cyclase-activating polypeptide (PA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd4dadd5d6b9dfe504bff78a5b953d83
https://doi.org/10.1523/jneurosci.0983-04.2004
https://doi.org/10.1523/jneurosci.0983-04.2004