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Autor:
Atsushi Takada, Chisa Ukawa, Tamaki Hirama, Howard B. Cottam, Roland K. Robins, Katsuhiko Nagahara, Shinji Sasaoka, Hiroko Kawano
Publikováno v:
Journal of Heterocyclic Chemistry. 31:239-243
A one-pot synthesis using 5-aminopyrazole derivatives 1 with ethoxymethylenemalononitrile (EMMN), ethyl ethoxymethylenecyanoacetate (EMCA) or diethyl ethoxymethylenemalonate (DEMM) gave pyrazolo-[1,5-a]pyrimidine compounds 2,4,8. Also, the one step r