Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Tamás Letoha"'
Autor:
Magdalena Kurtyka, Frank Wessely, Sarah Bau, Eseoghene Ifie, Liqun He, Nienke M. de Wit, Alberte Bay Villekjær Pedersen, Maximilian Keller, Caleb Webber, Helga E. de Vries, Olaf Ansorge, Christer Betsholtz, Marijke De Bock, Catarina Chaves, Birger Brodin, Morten S. Nielsen, Winfried Neuhaus, Robert D. Bell, Tamás Letoha, Axel H. Meyer, Germán Leparc, Martin Lenter, Dominique Lesuisse, Zameel M. Cader, Stephen T. Buckley, Irena Loryan, Claus U. Pietrzik
Publikováno v:
European Journal of Cell Biology, Vol 103, Iss 2, Pp 151406- (2024)
Despite extensive research, targeted delivery of substances to the brain still poses a great challenge due to the selectivity of the blood-brain barrier (BBB). Most molecules require either carrier- or receptor-mediated transport systems to reach the
Externí odkaz:
https://doaj.org/article/24cf1f3bfe6c41b79a62e5eaa26fce38
Publikováno v:
European Journal of Medicinal Chemistry Reports, Vol 8, Iss , Pp 100106- (2023)
We report a multi-step approach for the synthesis of protein-imprinted polymeric particles that selectively bind tumor necrosis factor alpha (TNFα). With high affinity for TNF-α, this type of polymer may provide a novel, safe treatment or preventiv
Externí odkaz:
https://doaj.org/article/052e5af2456a4b65b2e4384cdd0c12b3
Autor:
László Pecze, Kornélia Szabó, Márta Széll, Katalin Jósvay, Krisztián Kaszás, Erzsébet Kúsz, Tamás Letoha, János Prorok, István Koncz, András Tóth, Lajos Kemény, Csaba Vizler, Zoltán Oláh
Publikováno v:
PLoS ONE, Vol 3, Iss 10, p e3419 (2008)
BACKGROUND: Use of capsaicin or resiniferatoxin (RTX) as analgesics is an attractive therapeutic option. RTX opens the cation channel inflammatory pain/vanilloid receptor type 1 (TRPV1) permanently and selectively removes nociceptive neurons by Ca(2+
Externí odkaz:
https://doaj.org/article/52e58fa1720d48e69b6144ce633c6a70
Autor:
Zoltán Oláh, Katalin Jósvay, László Pecze, Tamás Letoha, Norbert Babai, Dénes Budai, Ferenc Otvös, Sándor Szalma, Csaba Vizler
Publikováno v:
PLoS ONE, Vol 2, Iss 6, p e545 (2007)
Ca(2+)-loaded calmodulin normally inhibits multiple Ca(2+)-channels upon dangerous elevation of intracellular Ca(2+) and protects cells from Ca(2+)-cytotoxicity, so blocking of calmodulin should theoretically lead to uncontrolled elevation of intrace
Externí odkaz:
https://doaj.org/article/f77ba262583840ebbceb6a0d8cd0e666
Autor:
Anett Hudák, Matthew Roach, Dávid Pusztai, Aladár Pettkó-Szandtner, Annamária Letoha, László Szilák, Mimoun Azzouz, Tamás Letoha
Publikováno v:
International Journal of Molecular Sciences
Volume 24
Issue 4
Pages: 3141
Volume 24
Issue 4
Pages: 3141
Due to their low pathogenicity, immunogenicity, and long-term gene expression, adeno-associated virus (AAV) vectors emerged as safe and efficient gene delivery tools, over-coming setbacks experienced with other viral gene delivery systems in early ge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5ef3672611614fe76b824c927931bd8
https://doi.org/10.3390/ijms24043141
https://doi.org/10.3390/ijms24043141
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 2; Pages: 796
International Journal of Molecular Sciences, Vol 23, Iss 796, p 796 (2022)
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 23, Iss 796, p 796 (2022)
International Journal of Molecular Sciences
Emerging SARS-CoV-2 variants pose threats to vaccination campaigns against COVID-19. Being more transmissible than the original virus, the SARS-CoV-2 B.1.617 lineage, named the Delta variant, swept through the world in 2021. The mutations in the Delt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5948622cd58637043331a36296432499
Autor:
Anett Hudák, Aladár Pettkó-Szandtner, Tamás Letoha, Katalin Jósvay, Martin Hofmann-Apitius, László Szilák, Erzsébet Kusz, Ildikó Domonkos
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-17 (2019)
Scientific Reports
Scientific Reports
Intraneuronal accumulation of amyloid-β(1–42) (Aβ1–42) is one of the earliest signs of Alzheimer’s disease (AD). Cell surface heparan sulfate proteoglycans (HSPGs) have profound influence on the cellular uptake of Aβ1–42 by mediating its a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65ed1aea99cf0c9c4be5d6205d3a0189
http://link.springer.com/article/10.1038/s41598-018-37476-9
http://link.springer.com/article/10.1038/s41598-018-37476-9
Autor:
Anett Hudák, Gareth Morgan, Jaromir Bacovsky, Roland Patai, Tamás F. Polgár, Annamária Letoha, Aladar Pettko-Szandtner, Csaba Vizler, László Szilák, Tamás Letoha
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 14; Pages: 7609
Despite the growing list of identified SARS-CoV-2 receptors, the human angiotensin-converting enzyme 2 (ACE2) is still viewed as the main cell entry receptor mediating SARS-CoV-2 internalization. It has been reported that wild-type mice, like other r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::316544885bf2a4ee621d7ef39f9b7e60
https://doi.org/10.3390/ijms23147609
https://doi.org/10.3390/ijms23147609
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 10
International Journal of Molecular Sciences, Vol 22, Iss 5336, p 5336 (2021)
Volume 22
Issue 10
International Journal of Molecular Sciences, Vol 22, Iss 5336, p 5336 (2021)
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a novel emerging pathogen causing an unprecedented pandemic in 21st century medicine. Due to the significant health and economic burden of the current SARS-CoV-2 outbreak, there is a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0024c4bbdd7f0b6c98cde889b64fe61
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a novel emerging pathogen causing an unprecedented pandemic in 21st century medicine. Due to the significant health and economic burden of the current SARS-CoV-2 outbreak, there is a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ee6f3841f65d119d16b346fb9058906f
https://doi.org/10.21203/rs.3.rs-70340/v1
https://doi.org/10.21203/rs.3.rs-70340/v1