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Autor:
Tallita Eduarda da Veiga, Morgana T. Castelo-Branco, Jesiel Cardoso, Gisele Cardoso Amorim, Mara S.P. Arruda, Alberto C. Arruda, Janaina Fernandes
Publikováno v:
JBIC Journal of Biological Inorganic Chemistry. 24:547-562
Massive lysis of tumor mass in cancer patients under chemotherapy regimens generates high levels of uric acid, leading to what is known as tumor lysis syndrome (TLS). Rasburicase, a recombinant urate oxidase, converts urate to allantoin, which is rea