Zobrazeno 1 - 10
of 368
pro vyhledávání: '"Tallie Z Baram"'
Publikováno v:
PLoS ONE, Vol 12, Iss 6, p e0180311 (2017)
Corticotropin releasing hormone (CRH) produced by the hypothalamus initiates the hypothalamic-pituitary-adrenal (HPA) axis, which regulates the body's stress response. CRH levels typically are undetectable in human plasma, but during pregnancy the pr
Externí odkaz:
https://doaj.org/article/fa69a35c6d3944e4bfa1d9f84ade9055
Autor:
Sophia C. Levis, Matthew T. Birnie, Yiyan Xie, Noriko Kamei, Puja V. Kulkarni, Johanna S. Montesinos, Christina R. Perrone, Catherine M. Cahill, Tallie Z. Baram, Stephen V. Mahler
Publikováno v:
Addiction Neuroscience, Vol 13, Iss , Pp 100175- (2024)
Opioid use disorder (OUD) is associated with a history of early-life adversity (ELA), an association that is particularly strong in women. In a rodent model, we previously found that ELA enhances risk for opioid addiction selectively in females, but
Externí odkaz:
https://doaj.org/article/8d64dd9956d94e94af54816248959924
Publikováno v:
Biological Psychiatry Global Open Science, Vol 4, Iss 6, Pp 100362- (2024)
Background: Exposure to adversity, including unpredictable environments, during early life is associated with neuropsychiatric illness in adulthood. One common factor in this sequela is anhedonia, the loss of responsivity to previously reinforcing st
Externí odkaz:
https://doaj.org/article/927168912dfe4bdfbcceae799c48a678
Autor:
Shawn McClelland, Gary P Brennan, Celine Dubé, Seeta Rajpara, Shruti Iyer, Cristina Richichi, Christophe Bernard, Tallie Z Baram
Publikováno v:
eLife, Vol 3 (2014)
The mechanisms generating epileptic neuronal networks following insults such as severe seizures are unknown. We have previously shown that interfering with the function of the neuron-restrictive silencer factor (NRSF/REST), an important transcription
Externí odkaz:
https://doaj.org/article/1988140a94ad4323a2aba1f399965d38
Autor:
Annabel K. Short, Ryan Weber, Noriko Kamei, Christina Wilcox Thai, Hina Arora, Ali Mortazavi, Hal S. Stern, Laura Glynn, Tallie Z. Baram
Publikováno v:
Neurobiology of Stress, Vol 31, Iss , Pp 100652- (2024)
Adverse early-life experiences (ELA) affect a majority of the world's children. Whereas the enduring impact of ELA on cognitive and emotional health is established, there are no tools to predict vulnerability to ELA consequences in an individual chil
Externí odkaz:
https://doaj.org/article/8c4ddf93e8574d83aedccd298453500f
Autor:
Christopher Hunt, Meghan Vinograd, Laura M. Glynn, Elysia Poggi Davis, Tallie Z. Baram, Hal Stern, Caroline Nievergelt, Bruna Cuccurazzu, Cindy Napan, Dylan Delmar, Dewleen G. Baker, Victoria B. Risbrough
Publikováno v:
Journal of Mood and Anxiety Disorders, Vol 6, Iss , Pp 100045- (2024)
High unpredictability has emerged as a dimension of early-life adversity that may contribute to a host of deleterious consequences later in life. Early-life unpredictability affects development of limbic and reward circuits in both rodents and humans
Externí odkaz:
https://doaj.org/article/1e6b105ae5f44f0399656d3ec4a7d6cf
Autor:
Carley A Karsten, Tallie Z Baram
Publikováno v:
Frontiers in Psychiatry, Vol 4 (2013)
Exciting information is emerging about epigenetic mechanisms and their role in long-lasting changes of neuronal gene expression. Whereas these mechanisms are active throughout life, recent findings point to a critical window of early postnatal develo
Externí odkaz:
https://doaj.org/article/3073b220b44d494889245aa61301593f
Autor:
Yuki Nakamura, Xiuyu Shi, Tomohiro Numata, Yasuo Mori, Ryuji Inoue, Christoph Lossin, Tallie Z Baram, Shinichi Hirose
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e80376 (2013)
Hyperpolarization-activated cyclic nucleotide-gated (HCN) channel-mediated currents, known as I h, are involved in the control of rhythmic activity in neuronal circuits and in determining neuronal properties including the resting membrane potential.
Externí odkaz:
https://doaj.org/article/6120173b343946e1a715a19f6ee02d49
Autor:
Matthew T. Birnie, Annabel K. Short, Gregory B. de Carvalho, Lara Taniguchi, Benjamin G. Gunn, Aidan L. Pham, Christy A. Itoga, Xiangmin Xu, Lulu Y. Chen, Stephen V. Mahler, Yuncai Chen, Tallie Z. Baram
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-10 (2023)
Reward circuit dysfunction is a mechanism for key emotional disorders that commonly arise after early life stresses (ELA). Here, the authors discover a projection from amygdala to nucleus accumbens that underlies ELA-induced reward deficits in mice.
Externí odkaz:
https://doaj.org/article/66e790ddc14546f682653fadabc8c1a6
Autor:
Annabel K. Short, Christina W. Thai, Yuncai Chen, Noriko Kamei, Aidan L. Pham, Matthew T. Birnie, Jessica L. Bolton, Ali Mortazavi, Tallie Z. Baram
Publikováno v:
Biological Psychiatry Global Open Science, Vol 3, Iss 1, Pp 99-109 (2023)
Background: Mental health and vulnerabilities to neuropsychiatric disorders involve the interplay of genes and environment, particularly during sensitive developmental periods. Early-life adversity (ELA) and stress promote vulnerabilities to stress-r
Externí odkaz:
https://doaj.org/article/36084c5dad3d4921b7406a533444ff1b