The IgG glycome of SARS-CoV-2 infected individuals reflects disease course and severity

Autor: Sterre L. Siekman, Tamas Pongracz, Wenjun Wang, Jan Nouta, Peter G. Kremsner, Pedro Vieira da Silva-Neto, Meral Esen, Andrea Kreidenweiss, Jana Held, Átila Alexandre Trapé, Rolf Fendel, Isabel Kinney Ferreira de Miranda Santos, Manfred Wuhrer, ImmunoCovid Consortium, Alessandro P. de Amorim, Jamille G M. Argolo, Rita de C.C. Barbieri, Marcelo Dias-Baruffi, Victor A F. Bastos, Vânia L D. Bonat, Cristina Ribeiro de Barros Cardoso, Ingryd Carmona-Garcia, Jonatan C S de Carvalho, Leticia F. Constant, Augusto M. Degiovani, Cassia F.S.L. Dias, Lúcia H. Faccioli, Marley R. Feitosa, Omar Feres, Ana Paula Morais Fernandes, Talita M. Fernandes, Thais F C. Fraga-Silva, Carlos Fuzo, Isabelle C. Guarneri, Cristiane M. Milanezi, Caroline T. Garbato, Gilberto Gambero Gaspar, Ângelo A.F. Júnior, Sandra R. Maruyama, Debora C. Nepomuceno, Nicola T. Neto, Camilla Narjara Simão Oliveira, Fátima M. Ostini, Rogerio S. Parra, Malena M. Pérez, Vinı́cius E. Pimentel, Giovanna da S. Porcel, José J R da Rocha, Lilian C. Rodrigues, Elisa M S. Russo, Dayane P. da Silva, Rafael C. da Silva, Carlos Arterio Sorgi, Camila O S. Souza, Diana M. Toro, Angelina L. Viana, Fernando Crivelenti Vilar, Ana C. Xavier, Kamila Zaparoli

Publikováno v: Frontiers in Immunology, Vol 13 (2022)

Immunoglobulin G (IgG) antibodies play an important role in the immune response against viruses such as SARS-CoV-2. As the effector functions of IgG are modulated by N-glycosylation of the Fc region, the structure and possible function of the IgG N-g

Externí odkaz: https://doaj.org/article/6158a9fbd2d94ee5a9418faadd9e7247

High plasma soluble levels of the immune checkpoint HLA-G molecule among bodybuilders.

Autor: Talita M Fernandes, Enrico F Puggina, Celso T Mendes-Junior, Milena C de Paula, Paulin Sonon, Eduardo A Donadi, Ana Paula M Fernandes

Publikováno v: PLoS ONE, Vol 15, Iss 9, p e0238044 (2020)

IntroductionStudies report that intense physical activity influences the down-regulation of immune function in athletes as well as the interaction between adipose tissue and the immune system.AimThis study aimed to compare the plasma soluble levels o

Externí odkaz: https://doaj.org/article/e1950a6de8c645aaa1d1ffe95c14efa0

The Severity of COVID-19 Affects the Plasma Soluble Levels of the Immune Checkpoint HLA-G Molecule

Autor: Jéssica F C, Cordeiro, Talita M, Fernandes, Diana M, Toro, Pedro V, da Silva-Neto, Vinícius E, Pimentel, Malena M, Pérez, Jonatan C S, de Carvalho, Thais F C, Fraga-Silva, Camilla N S, Oliveira, Jamille G M, Argolo, Augusto M, Degiovani, Fátima M, Ostini, Enrico F, Puginna, João S, da Silva, Isabel K F M, Santos, Vânia L D, Bonato, Cristina R B, Cardoso, Marcelo, Dias-Baruffi, Lúcia H, Faccioli, Eduardo A, Donadi, Carlos A, Sorgi, Ana P M, Fernandes, On Behalf Of The Immunocovid Study Group

Publikováno v: International Journal of Molecular Sciences; Volume 23; Issue 17; Pages: 9736

The non-classical histocompatibility antigen G (HLA-G) is an immune checkpoint molecule that has been implicated in viral disorders. We evaluated the plasma soluble HLA-G (sHLA-G) in 239 individuals, arranged in COVID-19 patients (n = 189) followed u

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc4bae3bda0503185478f7b34aad8f5d
https://doi.org/10.3390/ijms23179736

Plasma Sphingomyelin Disturbances: Unveiling Its Dual Role as a Crucial Immunopathological Factor and a Severity Prognostic Biomarker in COVID-19.

Autor: Toro, Diana Mota^1,2 (AUTHOR) dianamota.t@gmail.com, da Silva-Neto, Pedro V.^1,2 (AUTHOR) pedrovieira_sn11@hotmail.com, de Carvalho, Jonatan C. S.^1,3 (AUTHOR) avilela@usp.br, Fuzo, Carlos A.¹ (AUTHOR) cafuzo@usp.br, Pérez, Malena M.¹ (AUTHOR) malenac@usp.br, Pimentel, Vinícius E.^1,4 (AUTHOR) thaisfragasilva@gmail.com, Fraga-Silva, Thais F. C.⁴ (AUTHOR) imsantos@fmrp.usp.br, Oliveira, Camilla N. S.^1,4 (AUTHOR) camilla.narjara@outlook.com, Caruso, Glaucia R.¹ (AUTHOR) g_rigotto@hotmail.com, Vilela, Adriana F. L.³ (AUTHOR) pedronobre@usp.br, Nobre-Azevedo, Pedro^3,4 (AUTHOR) thiago.felippe@usp.br, Defelippo-Felippe, Thiago V.³ (AUTHOR), Argolo, Jamille G. M.⁵ (AUTHOR) jamilleargolo@usp.br, Degiovani, Augusto M.⁶ (AUTHOR) augustomd@msn.com, Ostini, Fátima M.⁶ (AUTHOR) tata_ostini@hotmail.com, Feitosa, Marley R.^7,8 (AUTHOR) fcvilar@gmail.com, Parra, Rogerio S.^7,8 (AUTHOR) rsparra@hcrp.usp.br, Vilar, Fernando C.^8,9 (AUTHOR) ggaspar@hcrp.usp.br, Gaspar, Gilberto G.⁹ (AUTHOR), Rocha, José J. R. da⁷ (AUTHOR) jjrocha1@bol.com.br

Publikováno v: Cells (2073-4409). Aug2023, Vol. 12 Issue 15, p1938. 23p.

Matrix Metalloproteinases on Severe COVID-19 Lung Disease Pathogenesis: Cooperative Actions of MMP-8/MMP-2 Axis on Immune Response through HLA-G Shedding and Oxidative Stress.

Autor: da Silva-Neto, Pedro V.^1,2 (AUTHOR) pedrovieira_sn11@hotmail.com, do Valle, Valéria B.³ (AUTHOR) valeriab.valle@usp.br, Fuzo, Carlos A.¹ (AUTHOR) cafuzo@usp.br, Fernandes, Talita M.⁴ (AUTHOR) talitafernandes@usp.br, Toro, Diana M.^1,2 (AUTHOR) dianamota.t@gmail.com, Fraga-Silva, Thais F. C.⁵ (AUTHOR) thaisfragasilva@usp.br, Basile, Patrícia A.³ (AUTHOR) pabasile@usp.br, de Carvalho, Jonatan C. S.^1,6 (AUTHOR) jonatancarvalho@usp.br, Pimentel, Vinícius E.^1,5 (AUTHOR) imsantos@fmrp.usp.br, Pérez, Malena M.¹ (AUTHOR) malenac@usp.br, Oliveira, Camilla N. S.^1,5 (AUTHOR) camilla.narjara@outlook.com, Rodrigues, Lilian C.¹ (AUTHOR) liktaldi@fcfrp.usp.br, Bastos, Victor A. F.¹ (AUTHOR) victor_ldn@hotmail.com, Tella, Sandra O. C.⁷ (AUTHOR) conde@fmrp.usp.br, Martins, Ronaldo B.⁸ (AUTHOR) ronaldobmjunior@gmail.com, Degiovani, Augusto M.⁹ (AUTHOR) augustomd@msn.com, Ostini, Fátima M.⁹ (AUTHOR) tata_ostini@hotmail.com, Feitosa, Marley R.¹⁰ (AUTHOR) mrfeitosa@hcrp.usp.br, Parra, Rogerio S.¹⁰ (AUTHOR) rsparra@hcrp.usp.br, Vilar, Fernando C.¹¹ (AUTHOR) fcvilar@gmail.com

Publikováno v: Biomolecules (2218-273X). May2022, Vol. 12 Issue 5, p604. 20p.