Drug Adverse Event Detection in Health Plan Data Using the Gamma Poisson Shrinker and Comparison to the Tree-based Scan Statistic

Autor: David Smith, Robert Reynolds, Marsha A. Raebel, Douglas Roblin, Margaret J. Gunter, Lisa Herrinton, Pamala A. Pawloski, Denise Boudreau, Susan E. Andrade, K. Arnold Chan, Taliser R. Avery, Robert L. Davis, Martin Kulldorff, Andrew Bate, Fang Zhang, Inna Dashevsky, Kenneth R. Petronis, Jeffrey S. Brown

Publikováno v: Pharmaceutics, Vol 5, Iss 1, Pp 179-200 (2013)

Background: Drug adverse event (AE) signal detection using the Gamma Poisson Shrinker (GPS) is commonly applied in spontaneous reporting. AE signal detection using large observational health plan databases can expand medication safety surveillance. M

Externí odkaz: https://doaj.org/article/8eb7d379bd084f9c9bcdc9bae0c49e43

13. INSPIRE-ASP Pneumonia Trial: A 59 Hospital Cluster Randomized Evaluation of INtelligent Stewardship Prompts to Improve Real-time Empiric Antibiotic Selection versus Routine Antibiotic Selection Practices for Patients with Pneumonia

Autor: Shruti K Gohil, Edward Septimus, Ken Kleinman, Neha Varma, Lauren Heim, Syma Rashid, Risa Rahm, William S Cooper, Naoise G Nickolay, Laura E McLean, Robert A Weinstein, Edward Rosen, Taliser R Avery, Sljivo Selsebil, Justin Vigeant, Kenneth Sands, Mandelin Cooper, H L Burgess, Julia Moody, Micaela H Coady, Gilbert F Rebecca, Kimberly N Smith, Brandon Carver, Caren Spencer-Smith, Russell Poland, Jason Hickok, S G Sturdevant, Anastasiia Weiland, Abinav Gowda, Robert Wolf, Mary K Hayden, Sujan Reddy, Melinda M Neuhauser, Arjun Srinivasan, David W Kubiak, John A Jernigan, Jonathan B Perlin, Richard Platt, Susan S Huang

Publikováno v: Open Forum Infectious Diseases

Background Up to 40% of hospitalized patients receive unnecessary or inappropriately broad antibiotics despite a low risk of multidrug-resistant organism (MDRO) infection. Empiric standard spectrum antibiotic use would reduce extended-spectrum (ES) a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3c4d4227afe2fa0b3d3d55dfd38d7c5
http://europepmc.org/articles/PMC8643995

Long-term care facilities: important participants of the acute care facility social network?

Autor: Bruce Y Lee, Yeohan Song, Sarah M Bartsch, Diane S Kim, Ashima Singh, Taliser R Avery, Shawn T Brown, S Levent Yilmaz, Kim F Wong, Margaret A Potter, Donald S Burke, Richard Platt, Susan S Huang

Publikováno v: PLoS ONE, Vol 6, Iss 12, p e29342 (2011)

Acute care facilities are connected via patient sharing, forming a network. However, patient sharing extends beyond this immediate network to include sharing with long-term care facilities. The extent of long-term care facility patient sharing on the

Externí odkaz: https://doaj.org/article/b88faa3a05e346b486f6977ac874c9aa

Chlorhexidine Versus Routine Bathing to Prevent Multi Drug-Resistant Organisms and All-Cause Bloodstream Infection in General Medical and Surgical Units: The ABATE Infection Cluster Randomized Trial

Autor: Micaela H Coady, Katherine Haffenreffer, Mary K. Hayden, Julie Lankiewicz, Adrijana Gombosev, Edward Septimus, Jalpa Sarup-Patel, Michael V. Murphy, Ken Kleinman, Julia Moody, Rebecca E. Kaganov, Jason Hickok, John A. Jernigan, Lauren Heim, Tyler Forehand, Jonathan B. Perlin, Richard Platt, Lena M. Portillo, Susan S. Huang, Taliser R. Avery, Robert A. Weinstein, Lauren Shimelman, Caren Spencer-Smith

Publikováno v: SSRN Electronic Journal.

Background: Universal skin and nasal decolonization reduces multidrug-resistant pathogens and bloodstream infections in intensive care units. The effect of universal decolonization on pathogens and infections in non-critical care units is unknown. Me

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::dd56f0d80d3e3b3f400507f57fdbe79e
https://doi.org/10.2139/ssrn.3214865

Cost Savings of Universal Decolonization to Prevent Intensive Care Unit Infection: Implications of the REDUCE MRSA Trial

Autor: Grace M. Lee, Julia Moody, Robert A. Weinstein, Richard Platt, G. Thomas Ray, Edward Septimus, Mary K. Hayden, Jonathan B. Perlin, Susan S. Huang, Jason Hickok, Taliser R. Avery

Publikováno v: Huang, SS; Septimus, E; Avery, TR; Lee, GM; Hickok, J; Weinstein, RA; et al.(2014). Cost savings of universal decolonization to prevent intensive care unit infection: Implications of the REDUCE MRSA trial. Infection Control and Hospital Epidemiology, 35, S23-S31. doi: 10.1086/677819. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/43g0531q
Infection control and hospital epidemiology, vol 35 Suppl 3, iss S3

Objective.To estimate and compare the impact on healthcare costs of 3 alternative strategies for reducing bloodstream infections in the intensive care unit (ICU): methicillin-resistant Staphylococcus aureus (MRSA) nares screening and isolation, targe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36bc34e83207a8dc4b2cadd8919f4c0a
https://doi.org/10.1086/677819