Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Talija Djordjevic"'
Publikováno v:
Journal of Cell Science
Journal of Cell Science; Vol 125
Journal of Cell Science; Vol 125
Urotensin-II (U-II) has been considered as one of the most potent vasoactive peptides, although its physiological and pathophysiological role is still not finally resolved. Recent evidence suggests that it promotes angiogenic responses in endothelial
Autor:
Agnes Görlach, Talija Djordjevic, Hans Hauner, Bernhard L. Bader, Rachida S. BelAiba, Isabelle Mack
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 297:E735-E748
Obesity is associated with a state of chronic low-grade inflammation. Immune cells accumulate in white adipose tissue (WAT). The vascular endothelium plays an interactive role in these infiltration and inflammatory processes. Mature and hypertrophic
Autor:
Armin Hatzelmann, Andreas Petry, Agnes Görlach, John Hess, Isabel Diebold, Talija Djordjevic, Hermann Tenor
Publikováno v:
Circulation Research. 104:1169-1177
Cyclic nucleotide phosphodiesterases (PDEs) control the levels of the second messengers cAMP and cGMP in many cell types including endothelial cells. Although PDE2 has the unique property to be activated by cGMP but to hydrolyze cAMP, its role in end
Publikováno v:
Thrombosis and Haemostasis. 100:1021-1028
SummaryPulmonary vascular remodeling is commonly associated with pulmonary hypertension and is characterized by media thickening and disordered cellular proliferation, often accompanied by fibrin deposition and thrombosis in situ. However, the signal
Autor:
Agnes Görlach, Steve Bonello, Rachida S. BelAiba, Thomas Kietzmann, Talija Djordjevic, Christian Zähringer, John R. Hess, Carine Michiels
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 27:755-761
Objective— Reactive oxygen species have been implicated as signaling molecules modulating the activity of redox-sensitive transcription factors such as nuclear factor kappa B (NF-κB). Recently, the transcription factor hypoxia-inducible factor-1 (
Publikováno v:
Antioxidants & Redox Signaling. 6:765-776
Various cardiovascular diseases including thrombosis, atherosclerosis, (pulmonary) hypertension and diabetes, are associated with disturbed coagulation. Alterations in the vessel wall common to many cardiovascular disorders have been shown to initiat
Publikováno v:
Antioxidants & Redox Signaling. 6:713-720
Pulmonary hypertension is associated with enhanced thrombogenicity of the vessel wall contributing to vascular remodeling. However, the signaling mechanisms promoting this prothrombotic state are not resolved. Here we investigated the role of the GTP
Autor:
Talija Djordjevic, Jeffrey R. Fineman, Andreas Petry, Rachida S. BelAiba, Isabel Diebold, Thomas Kietzmann, Christian Schreiber, Agnes Görlach, John R. Hess, Stephen M. Black, Sohrab Fratz
Publikováno v:
Antioxidantsredox signaling. 13(4)
Pulmonary vascular remodeling associated with pulmonary hypertension is characterized by media thickening, disordered proliferation, and in situ thrombosis. The p21-activated kinase-1 (PAK-1) can control growth, migration, and prothrombotic activity,
Publikováno v:
Thrombosis and haemostasis. 100(6)
Pulmonary vascular remodeling is commonly associated with pulmonary hypertension and is characterized by media thickening and disordered cellular proliferation, often accompanied by fibrin deposition and thrombosis in situ. However, the signaling pat
Autor:
Talija Djordjevic, Agnes Görlach
Publikováno v:
Thrombosis and haemostasis. 98(5)
SummaryUrotensin-II (UII) is an evolutionary conserved peptide which has been initially discovered in the urophysis of the fish goby regulating body fluid composition and vascular tone. Mammalian UII has gained increasing interest since it has been c