Zobrazeno 1 - 10
of 82
pro vyhledávání: '"Tali Mazor"'
Autor:
Suzanne J. Forrest, Hersh Gupta, Abigail Ward, Yvonne Y. Li, Duong Doan, Alyaa Al-Ibraheemi, Sanda Alexandrescu, Pratiti Bandopadhayay, Suzanne Shusterman, Elizabeth A. Mullen, Natalie B. Collins, Susan N. Chi, Karen D. Wright, Priti Kumari, Tali Mazor, Keith L. Ligon, Priyanka Shivdasani, Monica Manam, Laura E. MacConaill, Evelina Ceca, Sidney N. Benich, Wendy B. London, Richard L. Schilsky, Suanna S. Bruinooge, Jaime M. Guidry Auvil, Ethan Cerami, Barrett J. Rollins, Matthew L. Meyerson, Neal I. Lindeman, Bruce E. Johnson, Andrew D. Cherniack, Alanna J. Church, Katherine A. Janeway
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-11 (2024)
Abstract To inform clinical trial design and real-world precision pediatric oncology practice, we classified diagnoses, assessed the landscape of mutations, and identified genomic variants matching trials in a large unselected institutional cohort of
Externí odkaz:
https://doaj.org/article/4017a15f72474d229f7c23ceb2ec8422
Autor:
Suzanne J. Forrest, Hersh Gupta, Abigail Ward, Yvonne Y. Li, Duong Doan, Alyaa Al-Ibraheemi, Sanda Alexandrescu, Pratiti Bandopadhayay, Suzanne Shusterman, Elizabeth A. Mullen, Natalie B. Collins, Susan N. Chi, Karen D. Wright, Priti Kumari, Tali Mazor, Keith L. Ligon, Priyanka Shivdasani, Monica Manam, Laura E. MacConaill, Evelina Ceca, Sidney N. Benich, Wendy B. London, Richard L. Schilsky, Suanna S. Bruinooge, Jaime M. Guidry Auvil, Ethan Cerami, Barrett J. Rollins, Matthew L. Meyerson, Neal I. Lindeman, Bruce E. Johnson, Andrew D. Cherniack, Alanna J. Church, Katherine A. Janeway
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/fb4f1740ba5f49008685d912d84b0bbb
Autor:
Harry Klein, Tali Mazor, Ethan Siegel, Pavel Trukhanov, Andrea Ovalle, Catherine Del Vecchio Fitz, Zachary Zwiesler, Priti Kumari, Bernd Van Der Veen, Eric Marriott, Jason Hansel, Joyce Yu, Adem Albayrak, Susan Barry, Rachel B. Keller, Laura E. MacConaill, Neal Lindeman, Bruce E. Johnson, Barrett J. Rollins, Khanh T. Do, Brian Beardslee, Geoffrey Shapiro, Suzanne Hector-Barry, John Methot, Lynette Sholl, James Lindsay, Michael J. Hassett, Ethan Cerami
Publikováno v:
npj Precision Oncology, Vol 6, Iss 1, Pp 1-9 (2022)
Abstract Widespread, comprehensive sequencing of patient tumors has facilitated the usage of precision medicine (PM) drugs to target specific genomic alterations. Therapeutic clinical trials are necessary to test new PM drugs to advance precision med
Externí odkaz:
https://doaj.org/article/0c617a60fa3f432c8f9c2b34b3ebd0b8
Autor:
Elliot Stieglitz, Tali Mazor, Adam B. Olshen, Huimin Geng, Laura C. Gelston, Jon Akutagawa, Daniel B. Lipka, Christoph Plass, Christian Flotho, Farid F. Chehab, Benjamin S. Braun, Joseph F. Costello, Mignon L. Loh
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-8 (2017)
Juvenile myelomonocytic leukemia (JMML) is an aggressive disease with limited options for treatment. Here, the authors utilize DNA methylation based subgroups in JMML to predict clinical outcome.
Externí odkaz:
https://doaj.org/article/722c1dde424443b9b6f04f8e32625fea
Publikováno v:
PLoS Computational Biology, Vol 6, Iss 4, p e1000773 (2010)
Understanding the mechanistic basis of transcriptional regulation has been a central focus of molecular biology since its inception. New high-throughput chromatin immunoprecipitation experiments have revealed that most regulatory proteins bind thousa
Externí odkaz:
https://doaj.org/article/70175d8770a342abb17402b66779bc8a
Autor:
Brady Bernard, Shawn M. Sweeney, Thomas V. Yu, Nikolaus Schultz, Stephen-John Sammut, Andrea Ovalle, Tali Mazor, James Lindsay, Marilyn M. Li, Michele L. Lenoue-Newton, Priti Kumari, Haley Hunter-Zinck, Michelle F. Green, Matthew Galvin, Gary J. Doherty, Jeff P. Bruce, Jonathan L. Bell, Trevor J. Pugh
The American Association for Cancer Research (AACR) Project Genomics Evidence Neoplasia Information Exchange (GENIE) is an international pan-cancer registry with the goal to inform cancer research and clinical care worldwide. Founded in late 2015, th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::383af890dfc7179ff3a8ce8f4912b8d5
https://doi.org/10.1158/2159-8290.c.6549518.v1
https://doi.org/10.1158/2159-8290.c.6549518.v1
Autor:
Brady Bernard, Shawn M. Sweeney, Thomas V. Yu, Nikolaus Schultz, Stephen-John Sammut, Andrea Ovalle, Tali Mazor, James Lindsay, Marilyn M. Li, Michele L. Lenoue-Newton, Priti Kumari, Haley Hunter-Zinck, Michelle F. Green, Matthew Galvin, Gary J. Doherty, Jeff P. Bruce, Jonathan L. Bell, Trevor J. Pugh
Supplementary Table from AACR Project GENIE: 100,000 Cases and Beyond
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c493b80c6a8dd32c9e29bfea3efcadf
https://doi.org/10.1158/2159-8290.22540943
https://doi.org/10.1158/2159-8290.22540943
Autor:
Brady Bernard, Shawn M. Sweeney, Thomas V. Yu, Nikolaus Schultz, Stephen-John Sammut, Andrea Ovalle, Tali Mazor, James Lindsay, Marilyn M. Li, Michele L. Lenoue-Newton, Priti Kumari, Haley Hunter-Zinck, Michelle F. Green, Matthew Galvin, Gary J. Doherty, Jeff P. Bruce, Jonathan L. Bell, Trevor J. Pugh
Supplementary Figure from AACR Project GENIE: 100,000 Cases and Beyond
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17dd892c0f836423e7fa81c5d92a65e0
https://doi.org/10.1158/2159-8290.22540961
https://doi.org/10.1158/2159-8290.22540961
Autor:
Russell O. Pieper, Sabrina M. Ronen, Joseph F. Costello, Joanna J. Phillips, Robert J.A. Bell, Arie Perry, Kyle M. Walsh, Pavithra Viswanath, Roxanne E. Marshall, Tali Mazor, Lindsey Jones, Matthew Wood, Tracy T. Chow, Andrew Mancini, Tor-Christian Johannessen, Joydeep Mukherjee, Shigeo Ohba
Mutations in the isocitrate dehydrogenase gene IDH1 are common in low-grade glioma, where they result in the production of 2-hydroxyglutarate (2HG), disrupted patterns of histone methylation, and gliomagenesis. IDH1 mutations also cosegregate with mu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ccbc6812aa3e7c737ebce22a05b2b71b
https://doi.org/10.1158/0008-5472.c.6508757.v1
https://doi.org/10.1158/0008-5472.c.6508757.v1
Autor:
Jean L. Nakamura, Smita Bhatia, Kevin M. Shannon, Alice O. Nakamura, Joseph F. Costello, Rosanna Wustrack, Leslie L. Robison, Sue Hammond, Joseph P. Neglia, Robert E. Goldsby, Steven G. DuBois, Mignon Loh, Andrew E. Horvai, Ivan V. Smirnoff, Tali Mazor, Philip R. Davidson, Leah Lee, Katharine Yu, Vincent Lavergne, Amy L. Sherborne
Supplementary Figure 2 shows the exome coverage achieved with whole exome sequencing.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d62b416c87b586f6663230504c5b013
https://doi.org/10.1158/1078-0432.22464050
https://doi.org/10.1158/1078-0432.22464050