Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Tali Lerer-Goldshtein"'
Autor:
Rotem Rozenblat, Adi Tovin, David Zada, Ilana Lebenthal-Loinger, Tali Lerer-Goldshtein, Lior Appelbaum
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 5, p 2464 (2022)
Thyroid hormones (THs; T3 and T4) enter cells using specific transporters and regulate development and metabolism. Mutation in the TH transporter monocarboxylate transporter 8 (MCT8, SLC16A2) is associated with brain hypothyroidism and neurological i
Externí odkaz:
https://doaj.org/article/45b2961a3efa42b0be3372a189c83788
Publikováno v:
Disease Models & Mechanisms, Vol 9, Iss 11, Pp 1339-1348 (2016)
Hypomyelination is a key symptom of Allan-Herndon-Dudley syndrome (AHDS), a psychomotor retardation associated with mutations in the thyroid-hormone (TH) transporter MCT8 (monocarboxylate transporter 8). AHDS is characterized by severe intellectual d
Externí odkaz:
https://doaj.org/article/ad8e82d3212447ecb47fd5c2412a77d1
Autor:
Adi Shamay-Ramot, Khen Khermesh, Hagit T Porath, Michal Barak, Yishay Pinto, Chaim Wachtel, Alona Zilberberg, Tali Lerer-Goldshtein, Sol Efroni, Erez Y Levanon, Lior Appelbaum
Publikováno v:
PLoS Genetics, Vol 11, Iss 12, p e1005702 (2015)
Fragile X syndrome (FXS) is the most frequent inherited form of mental retardation. The cause for this X-linked disorder is the silencing of the fragile X mental retardation 1 (fmr1) gene and the absence of the fragile X mental retardation protein (F
Externí odkaz:
https://doaj.org/article/a926f0f2ecef4001bfe38aa8dd4fe5dc
Autor:
Laura Yelin-Bekerman, Idan Elbaz, Alex Diber, Dvir Dahary, Liron Gibbs-Bar, Shahar Alon, Tali Lerer-Goldshtein, Lior Appelbaum
Publikováno v:
eLife, Vol 4 (2015)
Sleep has been conserved throughout evolution; however, the molecular and neuronal mechanisms of sleep are largely unknown. The hypothalamic hypocretin/orexin (Hcrt) neurons regulate sleep\wake states, feeding, stress, and reward. To elucidate the me
Externí odkaz:
https://doaj.org/article/17b5780171184f48a75b4d0feb16498f
Publikováno v:
PLoS Genetics, Vol 10, Iss 9, p e1004615 (2014)
The mechanisms and treatment of psychomotor retardation, which includes motor and cognitive impairment, are indefinite. The Allan-Herndon-Dudley syndrome (AHDS) is an X-linked psychomotor retardation characterized by delayed development, severe intel
Externí odkaz:
https://doaj.org/article/56d1749d143e46c98fe405fac469095f
Autor:
Talya Wasserman-Bartov, Inbal Admati, Ilana Lebenthal-Loinger, Julia Sharabany, Tali Lerer-Goldshtein, Lior Appelbaum
Publikováno v:
J Neurosci
Thyroid hormones (THs), thyroxine (T4), and triiodothyronine (T3), regulate growth, metabolism, and neurodevelopment. THs secretion is controlled by the pituitary thyroid-stimulating hormone (TSH) and the hypothalamic–pituitary–thyroid (HPT) axis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69a41e29417a98cddc0b3510997ebe7a
https://europepmc.org/articles/PMC9653277/
https://europepmc.org/articles/PMC9653277/
Autor:
Dana Sagi, Tali Lerer-Goldshtein, Talia Levitas-Djerbi, Lior Appelbaum, Ilana Lebenthal-Loinger
Publikováno v:
Neuroendocrinology. 110:35-49
Background: Hypothalamic neurotensin (Nts)-secreting neurons regulate fundamental physiological processes including metabolism and feeding. However, the role of Nts in modulation of locomotor activity, sleep, and arousal is unclear. We previously ide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aaae52ec4dca9d53a0788f9454748231
https://doi.org/10.1159/000500590
https://doi.org/10.1159/000500590
Autor:
David Zada, Einat Blitz, Hiroki Matsuda, Yukihiko Kubota, Lior Appelbaum, Takuto Morikawa, Didier Y.R. Stainier, Tali Lerer-Goldshtein, Stefan Guenther
Publikováno v:
Endocrinology. 162
Hypothyroidism is a common pathological condition characterized by insufficient activity of the thyroid hormones (THs), thyroxine (T4), and 3,5,3′-triiodothyronine (T3), in the whole body or in specific tissues. Hypothyroidism is associated with in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb92a6253cb66aeac863bc179408f1fe
https://doi.org/10.1210/endocr/bqab047
https://doi.org/10.1210/endocr/bqab047
Autor:
Rotem Rozenblat, Lior Appelbaum, Adi Tovin, Einat Blitz, Tali Lerer-Goldshtein, David Zada, Talya Wasserman-Bartov, Inbal Admati
Publikováno v:
Thyroid : official journal of the American Thyroid Association. 30(1)
Background: The thyroid hormones (THs) triiodothyronine (T3) and thyroxine (T4) are crucial regulators of brain development and function. Cell-specific transporter proteins facilitate TH uptake and...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5a5fdec09d30f7ca55116af926cb8da
https://pubmed.ncbi.nlm.nih.gov/31797746
https://pubmed.ncbi.nlm.nih.gov/31797746
Sleep increases chromosome dynamics to enable reduction of accumulating DNA damage in single neurons
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
Sleep is essential to all animals with a nervous system. Nevertheless, the core cellular function of sleep is unknown, and there is no conserved molecular marker to define sleep across phylogeny. Time-lapse imaging of chromosomal markers in single ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ede2ed963d36d06830c1f121c3327bab
https://pubmed.ncbi.nlm.nih.gov/31211981
https://pubmed.ncbi.nlm.nih.gov/31211981