Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Talang Wang"'
Autor:
Talang Wang, Ruoyu Zhao, Junhong Zhi, Ziling Liu, Aiwei Wu, Zimei Yang, Weixu Wang, Ting Ni, Lili Jing, Ming Yu
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-17 (2023)
Abstract HMG protein Tox4 is a regulator of PP1 phosphatases with unknown function in development. Here we show that Tox4 conditional knockout in mice reduces thymic cellularity, partially blocks T cell development, and decreases ratio of CD8 to CD4
Externí odkaz:
https://doaj.org/article/a56d8837ba52408aa2688a8a827130fe
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-15 (2022)
As a role of TOX4, one of the regulatory proteins of PP1 phosphatases, in transcriptional regulation, authors here show that TOX4 restricts pause release and early productive elongation, and promotes Pol II recycling and transcriptional reinitiation.
Externí odkaz:
https://doaj.org/article/a4083f47b8634325832b58b1f1446990
Publikováno v:
SSRN Electronic Journal.
Protein phosphatase 1 complex (PP1C), consisting of one of the phosphatases, PP1α, β and γ, and three regulatory subunits, PNUTS, TOX4 and WDR82, plays critical roles in gene regulation and is mutated in over 20% of uterine corpus endometrial carc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a2b1f0da6ca88785dedb40e1b55a3232
https://doi.org/10.2139/ssrn.3823429
https://doi.org/10.2139/ssrn.3823429